CD80 Monoclonal Antibody (MEM-233) | Invitrogen MA1-19215 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD80 Monoclonal Antibody (MEM-233)

catalog :

MA1-19215

quantity :

100 µg

price :

US 344

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MEM-233

reactivity :

African green monkey, human

application :

immunocytochemistry, immunoprecipitation, flow cytometry

more info or order :

Invitrogen product webpage

citations: 15

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human	Fricke F, Beaudouin J, Eils R, Heilemann M. One, two or three? Probing the stoichiometry of membrane proteins by single-molecule localization microscopy. Sci Rep. 2015;5:14072 pubmed publisher
flow cytometry; human	Avanzi S, Leoni V, Rotola A, Alviano F, Solimando L, Lanzoni G, et al. Susceptibility of human placenta derived mesenchymal stromal/stem cells to human herpesviruses infection. PLoS ONE. 2013;8:e71412 pubmed publisher
flow cytometry; human; fig 1	Tanaka M, Krutzik S, Sieling P, Lee D, Rea T, Modlin R. Activation of Fc gamma RI on monocytes triggers differentiation into immature dendritic cells that induce autoreactive T cell responses. J Immunol. 2009;183:2349-55 pubmed publisher
flow cytometry; human; fig 3	Stephens T, Nikoopour E, Rider B, Leon Ponte M, Chau T, Mikolajczak S, et al. Dendritic cell differentiation induced by a self-peptide derived from apolipoprotein E. J Immunol. 2008;181:6859-71 pubmed
flow cytometry; human; fig 4	Lee D, Sieling P, Ochoa M, Krutzik S, Guo B, Hernandez M, et al. LILRA2 activation inhibits dendritic cell differentiation and antigen presentation to T cells. J Immunol. 2007;179:8128-36 pubmed
flow cytometry; African green monkey	Daubenberger C, Spirig R, Patarroyo M, Pluschke G. Flow cytometric analysis on cross-reactivity of human-specific CD monoclonal antibodies with splenocytes of Aotus nancymaae, a non-human primate model for biomedical research. Vet Immunol Immunopathol. 2007;119:14-20 pubmed
flow cytometry; human	Gigli G, Caielli S, Cutuli D, Falcone M. Innate immunity modulates autoimmunity: type 1 interferon-beta treatment in multiple sclerosis promotes growth and function of regulatory invariant natural killer T cells through dendritic cell maturation. Immunology. 2007;122:409-17 pubmed
flow cytometry; human; tbl 1	Kolar G, Mehta D, Pelayo R, Capra J. A novel human B cell subpopulation representing the initial germinal center population to express AID. Blood. 2007;109:2545-52 pubmed
flow cytometry; human; tbl 2 immunocytochemistry; human; fig 2d	Sandilands G, McCrae J, Hill K, Perry M, Baxter D. Major histocompatibility complex class II (DR) antigen and costimulatory molecules on in vitro and in vivo activated human polymorphonuclear neutrophils. Immunology. 2006;119:562-71 pubmed
flow cytometry; human	Summers K, Marleau A, Mahon J, McManus R, Hramiak I, Singh B. Reduced IFN-alpha secretion by blood dendritic cells in human diabetes. Clin Immunol. 2006;121:81-9 pubmed
flow cytometry; human	Campioni D, Moretti S, Ferrari L, Punturieri M, Castoldi G, Lanza F. Immunophenotypic heterogeneity of bone marrow-derived mesenchymal stromal cells from patients with hematologic disorders: correlation with bone marrow microenvironment. Haematologica. 2006;91:364-8 pubmed
flow cytometry; human	Game D, Rogers N, Lechler R. Acquisition of HLA-DR and costimulatory molecules by T cells from allogeneic antigen presenting cells. Am J Transplant. 2005;5:1614-25 pubmed
flow cytometry; human; fig 6	Sandilands G, Ahmed Z, Perry N, Davison M, Lupton A, Young B. Cross-linking of neutrophil CD11b results in rapid cell surface expression of molecules required for antigen presentation and T-cell activation. Immunology. 2005;114:354-68 pubmed
flow cytometry; human	Zingoni A, Sornasse T, Cocks B, Tanaka Y, Santoni A, Lanier L. Cross-talk between activated human NK cells and CD4+ T cells via OX40-OX40 ligand interactions. J Immunol. 2004;173:3716-24 pubmed
	Morbach H, Wiegering V, Richl P, Schwarz T, Suffa N, Eichhorn E, et al. Activated memory B cells may function as antigen-presenting cells in the joints of children with juvenile idiopathic arthritis. Arthritis Rheum. 2011;63:3458-66 pubmed publisher

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product information

Product Type :

Antibody

Product Name :

CD80 Monoclonal Antibody (MEM-233)

Catalog # :

MA1-19215

Quantity :

100 µg

Price :

US 344

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 1-4 µg/mL, Immunoprecipitation: Assay-dependent

Species :

Human

Clone :

MEM-233

Isotype :

IgG1

Storage :

4° C, do not freeze

Description :

CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28, and of an inhibitory receptor CTLA-4 (CD152). Both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, and both molecules can also substitute for each other in this process. CD80 is rapidly induced on the surface of in vitro activated B cells, with Epstein Barr Virus (EBV) transformed B cell lines, with Burkitts lymphoma cell lines, with freshly isolated follicular B lymphoma cells, T cells, and monocytes. The B-lymphocyte activation antigen B7-1 provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 and CTLA4 ligands of T cells. Diseases associated with CD80 dysfunction include gallbladder squamous cell carcinoma and myocarditis.

Immunogen :

Extracellular domain of human CD80 fused to human IgG1(Fc).

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1-4 µg/mL, Immunoprecipitation: Assay-dependent

Aliases :

Activation B7-1 antigen; B7; B7 protein; B7.1; B71; B7-1; B7-1 protein; B7-1 protein precursor; BB1; B-lymphocyte activation antigen B7; Cd28l; CD28LG; CD28LG1; CD80; Cd80 a rat homolog of the human CD28/CTLA - 4 ligand (B7-1); CD80 anitgen; CD80 antigen; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); Cd80 molecule; CD80 protein precursor; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; LAB7; Ly53; Ly-53; MIC17; sCD 80; sCD80; secreted B7-1 protein precursor; soluble CD 80; soluble CD80; T-cell costimulatory molecule; T-cell co-stimulatory protein B7-1; T-lymphocyte activation antigen CD80; TS/A-1; TSA1

more info or order :

Invitrogen product webpage