This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
BrdU Monoclonal Antibody (MoBU-1)
catalog :
MA1-19213
quantity :
100 ug
price :
US 389.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MoBu-1
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - free floating section
citations: 30
Reference
Sun J, Belke D, Gui Y, Chen Y, Zhou S, Zheng X. Polo-like kinase 4 inhibitor CFI-400945 inhibits carotid arterial neointima formation but increases atherosclerosis. Cell Death Discov. 2023;9:49 pubmed publisher
Middelkamp M, Ruck L, Krisp C, Sumisławski P, Mohammadi B, Dottermusch M, et al. Overexpression of Lin28A in neural progenitor cells in vivo does not lead to brain tumor formation but results in reduced spine density. Acta Neuropathol Commun. 2021;9:185 pubmed publisher
Czarnek M, Sarad K, Karaś A, Kochan J, Bereta J. Non-targeting control for MISSION shRNA library silences SNRPD3 leading to cell death or permanent growth arrest. Mol Ther Nucleic Acids. 2021;26:711-731 pubmed publisher
Kim C, Jin J, Ye Z, Jadhav R, Gustafson C, Hu B, et al. Histone deficiency and accelerated replication stress in T cell aging. J Clin Invest. 2021;131: pubmed publisher
Schilling E, Scherer M, Rothemund F, Stamminger T. Functional regulation of the structure-specific endonuclease FEN1 by the human cytomegalovirus protein IE1 suggests a role for the re-initiation of stalled viral replication forks. PLoS Pathog. 2021;17:e1009460 pubmed publisher
Sandoval M, Ying Z, Beronja S. Interplay of opposing fate choices stalls oncogenic growth in murine skin epithelium. elife. 2021;10: pubmed publisher
Cai E, Kufeld M, Schuster S, Arora S, Larkin M, Germanos A, et al. Selective Translation of Cell Fate Regulators Mediates Tolerance to Broad Oncogenic Stress. Cell Stem Cell. 2020;: pubmed publisher
Morales Torres C, Wu M, Hobor S, Wainwright E, Martin M, Patel H, et al. Selective inhibition of cancer cell self-renewal through a Quisinostat-histone H1.0 axis. Nat Commun. 2020;11:1792 pubmed publisher
Schoof M, Launspach M, Holdhof D, Nguyen L, Engel V, Filser S, et al. The transcriptional coactivator and histone acetyltransferase CBP regulates neural precursor cell development and migration. Acta Neuropathol Commun. 2019;7:199 pubmed publisher
Roy A, Ghosh A, Kumar B, Chandran B. IFI16, a nuclear innate immune DNA sensor, mediates epigenetic silencing of herpesvirus genomes by its association with H3K9 methyltransferases SUV39H1 and GLP. elife. 2019;8: pubmed publisher
Arreal L, Piva M, Fernandez S, Revandkar A, Schaub Clerigué A, Villanueva J, et al. Targeting PML in triple negative breast cancer elicits growth suppression and senescence. Cell Death Differ. 2019;: pubmed publisher
Perl A, O Connor C, Fa P, Mayca Pozo F, Zhang J, Zhang Y, et al. Protein phosphatase 2A controls ongoing DNA replication by binding to and regulating cell division cycle 45 (CDC45). J Biol Chem. 2019;294:17043-17059 pubmed publisher
Huycke T, Miller B, Gill H, Nerurkar N, Sprinzak D, Mahadevan L, et al. Genetic and Mechanical Regulation of Intestinal Smooth Muscle Development. Cell. 2019;179:90-105.e21 pubmed publisher
Bechshøft C, Jensen S, Schjerling P, Andersen J, Svensson R, Eriksen C, et al. Age and prior exercise in vivo determine the subsequent in vitro molecular profile of myoblasts and nonmyogenic cells derived from human skeletal muscle. Am J Physiol Cell Physiol. 2019;316:C898-C912 pubmed publisher
James K, Cosway E, LUCAS B, White A, Parnell S, Carvalho Gaspar M, et al. Endothelial cells act as gatekeepers for LTβR-dependent thymocyte emigration. J Exp Med. 2018;215:2984-2993 pubmed publisher
Disson O, Blériot C, Jacob J, Serafini N, Dulauroy S, Jouvion G, et al. Peyer's patch myeloid cells infection by Listeria signals through gp38+ stromal cells and locks intestinal villus invasion. J Exp Med. 2018;215:2936-2954 pubmed publisher
Valcarcel Jimenez L, Macchia A, Martin Martin N, Cortazar A, Schaub Clerigué A, Pujana Vaquerizo M, et al. Integrative analysis of transcriptomics and clinical data uncovers the tumor-suppressive activity of MITF in prostate cancer. Cell Death Dis. 2018;9:1041 pubmed publisher
Chen C, Zhai S, Zhang L, Chen J, Long X, Qin J, et al. Uhrf1 regulates germinal center B cell expansion and affinity maturation to control viral infection. J Exp Med. 2018;215:1437-1448 pubmed publisher
Mayer C, Gazumyan A, Kara E, Gitlin A, Golijanin J, Viant C, et al. The microanatomic segregation of selection by apoptosis in the germinal center. Science. 2017;358: pubmed publisher
Kumagai A, Dunphy W. MTBP, the partner of Treslin, contains a novel DNA-binding domain that is essential for proper initiation of DNA replication. Mol Biol Cell. 2017;28:2998-3012 pubmed publisher
Fan Y, Mok C, Chan M, Zhang Y, Nal B, Kien F, et al. Cell Cycle-independent Role of Cyclin D3 in Host Restriction of Influenza Virus Infection. J Biol Chem. 2017;292:5070-5088 pubmed publisher
Al Taweel F, Douglas C, Whawell S. The Periodontal Pathogen Porphyromonas gingivalis Preferentially Interacts with Oral Epithelial Cells in S Phase of the Cell Cycle. Infect Immun. 2016;84:1966-1974 pubmed publisher
Lo C, Weil B, Palka B, Momeni A, Canty J, Neelamegham S. Cell surface glycoengineering improves selectin-mediated adhesion of mesenchymal stem cells (MSCs) and cardiosphere-derived cells (CDCs): Pilot validation in porcine ischemia-reperfusion model. Biomaterials. 2016;74:19-30 pubmed publisher
Jiang Q, Paramasivam M, Aressy B, Wu J, Bellani M, Tong W, et al. MERIT40 cooperates with BRCA2 to resolve DNA interstrand cross-links. Genes Dev. 2015;29:1955-68 pubmed publisher
Shen Z, Stanger B. YAP regulates S-phase entry in endothelial cells. PLoS ONE. 2015;10:e0117522 pubmed publisher
Holder G, McGary C, Johnson E, Zheng R, John V, Sugimoto C, et al. Expression of the mannose receptor CD206 in HIV and SIV encephalitis: a phenotypic switch of brain perivascular macrophages with virus infection. J Neuroimmune Pharmacol. 2014;9:716-26 pubmed publisher
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Wu Y, Huang S, Nan F, Chang C, Hsiao C, Lai K, et al. Over-inhibition of NADPH oxidase reduce the wound healing in liver of finfish. Fish Shellfish Immunol. 2014;40:174-81 pubmed publisher
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product information
Product Type :
Antibody
Product Name :
BrdU Monoclonal Antibody (MoBU-1)
Catalog # :
MA1-19213
Quantity :
100 ug
Price :
US 389.00
Clonality :
Monoclonal
Purity :
protein A
Host :
Mouse
Reactivity :
Chemical
Applications :
Flow Cytometry: 1-2 ug/mL, Immunocytochemistry: 2 ug/mL, Immunohistochemistry (Paraffin): Assay-dependent
Species :
Chemical
Clone :
MoBU-1
Isotype :
IgG1
Storage :
4 C, do not freeze
Description :
Bromodeoxyuridine (5-bromo-2-deoxyuridine, BrdU) is a synthetic nucleoside that is an analogue of thymidine. BrdU is commonly used in the detection of proliferating cells in living tissues, and can be incorporated into the newly synthesized DNA of replicating cells (during the S phase of the cell cycle), substituting for thymidine during DNA replication. Antibodies specific for BrdU can then be used to detect the incorporated chemical, thus indicating cells that were actively replicating their DNA. Binding of the antibody requires denaturation of the DNA, usually by exposing the cells to acid or heat.
Immunogen :
BrdU conjugated to hemocyanine.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1-2 ug/mL, Immunocytochemistry: 2 ug/mL, Immunohistochemistry (Paraffin): Assay-dependent
Aliases :
5-Bromo-2-deoxyuridine; Bromodeoxyuridine
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA