GFAP Monoclonal Antibody (GF-01) | Invitrogen MA1-19170 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

GFAP Monoclonal Antibody (GF-01)

catalog :

MA1-19170

quantity :

100 µg

price :

US 371

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

GF-01

reactivity :

human, pigs , cat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:1000	Duan Y, Miao L, Ye H, Yang C, Fu B, Schwartz P, et al. A faster immunofluorescence assay for tracking infection progress of human cytomegalovirus. Acta Biochim Biophys Sin (Shanghai). 2012;44:597-605 pubmed publisher

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image 1 :

product information

Product Type :

Antibody

Product Name :

GFAP Monoclonal Antibody (GF-01)

Catalog # :

MA1-19170

Quantity :

100 µg

Price :

US 371

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Feline, Human, Porcine

Applications :

Immunocytochemistry: 5-10 µg/mL, Immunohistochemistry (Paraffin): 10 µg/mL, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Species :

Feline, Human, Porcine

Clone :

GF-01

Isotype :

IgG1

Storage :

4° C, do not freeze

Description :

GFAP (Glial fibrillary acidic protein) is a member of the class III intermediate filament protein family. GFAP is heavily and specifically expressed in astrocytes and certain astroglia of the central nervous system, in satellite cells of peripheral ganglia, and in non-myelinating Schwann cells of peripheral nerves. In addition, neural stem cells strongly express GFAP. Antibodies to GFAP are very useful as markers of astrocytic cells. In addition, many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes. GFAP is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing of the GFAP gene results in multiple transcript variants encoding distinct isoforms.

Immunogen :

Pellet of pig brain cold-stable proteins after depolymerization of Microtubules.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 5-10 µg/mL, Immunohistochemistry (Paraffin): 10 µg/mL, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Aliases :

6330404F12Rik; 65 kDa glutamic acid decarboxylase; AI836096; ALXDRD; Astrocyte or Intermediate Filament Protein; cb345; class III intermediate filament protein; etID36982.3; FLJ45472; GAD(65); Gad2; Gad-2; GAD65; GAD-65; GFAP; GFAP epsilon; gfap protein; gfapl; glial fibrillary acidic protein; Glial Fibrillary Acidic Protein (GFAP); glial fibrillary acidic protein alpha; glutamate decarboxylase 2; Glutamate decarboxylase 65 kDa isoform; glutamic acid decarboxylase 2; I79_011607; intermediate filament; intermediate filament protein; intermediate filament protein; GFAP; Unknown (protein for MGC:139638); wu:fb34h11; wu:fk42c12; xx:af506734; zgc:110485; zGFAP; intermediate filament protein; zrf-1 antigen

more info or order :

Invitrogen product webpage