HLA-DR/DP Monoclonal Antibody (HL-38) | Invitrogen MA1-19145 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

HLA-DR/DP Monoclonal Antibody (HL-38)

catalog :

MA1-19145

quantity :

100 µg

price :

US 322

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

HL-38

reactivity :

human

application :

western blot, immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; 4 ug/ml	McIlroy D, Troadec C, Grassi F, Samri A, Barrou B, Autran B, et al. Investigation of human spleen dendritic cell phenotype and distribution reveals evidence of in vivo activation in a subset of organ donors. Blood. 2001;97:3470-7 pubmed
flow cytometry; human; fig 3	Schiff D, Rae J, Martin T, Davis B, Curnutte J. Increased phagocyte Fc gammaRI expression and improved Fc gamma-receptor-mediated phagocytosis after in vivo recombinant human interferon-gamma treatment of normal human subjects. Blood. 1997;90:3187-94 pubmed
flow cytometry; human	Genc K, Dona D, Reder A. Increased CD80(+) B cells in active multiple sclerosis and reversal by interferon beta-1b therapy. J Clin Invest. 1997;99:2664-71 pubmed

product information

Product Type :

Antibody

Product Name :

HLA-DR/DP Monoclonal Antibody (HL-38)

Catalog # :

MA1-19145

Quantity :

100 µg

Price :

US 322

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Porcine

Applications :

Flow Cytometry: 1-4 µg/mL, Immunohistochemistry (Paraffin): Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Species :

Human, Porcine

Clone :

HL-38

Isotype :

IgG2a

Storage :

4° C, do not freeze

Description :

HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq, Jul 2008].

Immunogen :

Burkitt's lymphoma cell line Raji.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1-4 µg/mL, Immunohistochemistry (Paraffin): Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Aliases :

beta1 domain MHC class II HLA DPB; class II HLA beta chain; Clone P2-beta-3; DPB1; DR-16; DRB1; DRw10; DW2.2/DR2.2; HLA class II histocompatibility antigen, DP beta 1 chain; HLA class II histocompatibility antigen, DP(W4) beta chain; HLA class II histocompatibility antigen, DR-1 beta chain; HLA class II histocompatibility antigen, DRB1-15 beta chain; HLA class II histocompatibility antigen, DRB1-16 beta chain; HLA class II histocompatibility antigen, DRB1-3 chain; HLA DP14-beta chain; HLA-D; HLA-DP; HLA-DP histocompatibility type, beta-1 subunit; HLA-DP1B; HLA-DPB; HLA-DPB1; HLA-DR; HLA-DR1B; HLA-DRB; HLA-DRB1; HLA-DRB2; human leucocyte antigen DRB1; lymphocyte antigen DRB1; major histocompatibility complex class II antigen beta chain; major histocompatibility complex, class II, DP beta 1; major histocompatibility complex, class II, DR beta 1; MHC Class 2; MHC class II; MHC class II antigen; MHC class II antigen beta chain; MHC class II antigen DP beta 1 chain; MHC class II antigen DPB1; MHC class II antigen DPbeta1; MHC class II antigen DRB1*15; MHC class II antigen DRB1*16; MHC class II antigen DRB1*3; MHC class II HLA-DP-beta-1; MHC class II HLA-DR beta 1 chain; MHC class II HLA-DRB1; MHC class II HLA-DR-beta cell surface glycoprotein; MHC class II HLA-DRw10-beta; MHC HLA DPB1; MHC HLA-D; MHC II HLA; SS1

more info or order :

Invitrogen product webpage