ICAM-1 Monoclonal Antibody (MEM-111) | Invitrogen MA1-19123 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ICAM-1 Monoclonal Antibody (MEM-111)

catalog :

MA1-19123

quantity :

100 µg

price :

US 389.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MEM-111

reactivity :

human, rat, bovine

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; tbl 3	Fromm J, Thomas A, Wood B. Characterization and Purification of Neoplastic Cells of Nodular Lymphocyte Predominant Hodgkin Lymphoma from Lymph Nodes by Flow Cytometry and Flow Cytometric Cell Sorting. Am J Pathol. 2017;187:304-317 pubmed publisher
flow cytometry; human; fig 6	Lee D, Li H, Ochoa M, Tanaka M, Carbone R, Damoiseaux R, et al. Integrated pathways for neutrophil recruitment and inflammation in leprosy. J Infect Dis. 2010;201:558-69 pubmed publisher
flow cytometry; human; fig 4	Lee D, Sieling P, Ochoa M, Krutzik S, Guo B, Hernandez M, et al. LILRA2 activation inhibits dendritic cell differentiation and antigen presentation to T cells. J Immunol. 2007;179:8128-36 pubmed
flow cytometry; human	Fromm J, Kussick S, Wood B. Identification and purification of classical Hodgkin cells from lymph nodes by flow cytometry and flow cytometric cell sorting. Am J Clin Pathol. 2006;126:764-80 pubmed
flow cytometry; human; fig 6	Zhang F, Marcus W, Goyal N, Selvaraj P, Springer T, Zhu C. Two-dimensional kinetics regulation of alphaLbeta2-ICAM-1 interaction by conformational changes of the alphaL-inserted domain. J Biol Chem. 2005;280:42207-18 pubmed
flow cytometry; human	Semnani R, Sabzevari H, Iyer R, Nutman T. Filarial antigens impair the function of human dendritic cells during differentiation. Infect Immun. 2001;69:5813-22 pubmed
	Basehore S, Bohlman S, Weber C, Swaminathan S, Zhang Y, Jang C, et al. Laminar Flow on Endothelial Cells Suppresses eNOS O-GlcNAcylation to Promote eNOS Activity. Circ Res. 2021;129:1054-1066 pubmed publisher
	Taechangam N, Iyer S, Walker N, Arzi B, Borjesson D. Mechanisms utilized by feline adipose-derived mesenchymal stem cells to inhibit T lymphocyte proliferation. Stem Cell Res Ther. 2019;10:188 pubmed publisher

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product information

Product Type :

Antibody

Product Name :

ICAM-1 Monoclonal Antibody (MEM-111)

Catalog # :

MA1-19123

Quantity :

100 µg

Price :

US 389.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Bovine, Human, Rat

Applications :

ELISA: Assay-dependent, Flow Cytometry: 0.5-4 µg/mL, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Paraffin): 10 µg/mL, Western Blot: 1-2 µg/mL

Species :

Bovine, Human, Rat

Clone :

MEM-111

Isotype :

IgG2a

Storage :

4° C, do not freeze

Description :

ICAM-1 (CD54) is an 85-110 kDa single-chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. ICAM-1 has 7 potential N-linked glycosylation sites and shares considerable amino acid sequence homology with ICAM-3 (CD50) and ICAM-2 (CD102). ICAM-1 binds to integrins of type CD11a/CD18 (leukocyte adhesion molecule, LFA-1), or CD11b/CD18 (Mac-1) and is exploited by Rhinovirus as a receptor. ICAM-1 is expressed by activated endothelial cells and detected on epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase upon inflammation. ICAM-1 is also detected in some carcinoma and melanoma cells. Soluble ICAM-1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes.

Immunogen :

Burkitt's lymphoma cell line Raji.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Flow Cytometry: 0.5-4 µg/mL, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Paraffin): 10 µg/mL, Western Blot: 1-2 µg/mL

Aliases :

BB2; CD54; cell surface glycoprotein P3.58; Human rhinovirus receptor; ICAM; Icam1; ICAM-1; ICAM-1; CD54 homolog; Intercellular adhesion molecule 1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; intercellular adhesion molecule-1; intercellular adhesion molecule-1 precursor; Ly 47; Ly-47; major group rhinovirus receptor; MALA2; MALA-2; MyD10; P3.58; sCD54; soluble CD54; Surface antigen of activated B cells

more info or order :

Invitrogen product webpage