ECM1 Monoclonal Antibody (SC-05) | Invitrogen MA1-19051 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ECM1 Monoclonal Antibody (SC-05)

catalog :

MA1-19051

quantity :

100 µg

price :

US 365.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

SC-05

reactivity :

human, rat

application :

western blot, ELISA, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
ELISA; human; 1:500	Eda N, Shimizu K, Suzuki S, Tanabe Y, Lee E, Akama T. Altered secretory immunoglobulin A on skin surface after intensive exercise. J Strength Cond Res. 2013;27:2581-7 pubmed publisher
immunohistochemistry - paraffin section; rat; loading ...; fig 1b	Tang Q, Tao K, Yun Liu -, Sun X, Geng M, Jiang C. Immunocytochemical localization of secretory component in Paneth cell secretory granules-rat Paneth cells participate in acquired immunity. J Mol Histol. 2005;36:331-5 pubmed

product information

Product Type :

Antibody

Product Name :

ECM1 Monoclonal Antibody (SC-05)

Catalog # :

MA1-19051

Quantity :

100 µg

Price :

US 365.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

Immunohistochemistry (Frozen): 2-8 µg/mL, Immunohistochemistry (Paraffin): Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Species :

Human

Clone :

SC-05

Isotype :

IgG1

Storage :

4° C, do not freeze

Description :

ECM1, also referred to as extracellular matrix protein 1, is a protein that plays a significant role in regulating extracellular matrix organization and cell adhesion. It is expressed in various tissues, including the skin, lung, and liver, and is involved in the development and progression of several diseases, including cancer and dermatological disorders. The protein interacts with several extracellular matrix proteins, such as collagen and fibronectin, and is involved in the regulation of cell proliferation, migration, and invasion. ECM1 is also involved in endochondral bone formation, angiogenesis, and tumor biology. It interacts with various extracellular and structural proteins, contributing to the maintenance of skin integrity and homeostasis. Mutations in this gene are associated with lipoid proteinosis disorder (also known as hyalinosis cutis et mucosae or Urbach-Wiethe disease) that is characterized by generalized thickening of skin, mucosae, and certain viscera. Different isoforms of ECM1 have been described in alternatively spliced transcript variants. Diseases associated with ECM1 include Lipoid Proteinosis Of Urbach And Wiethe and Lichen Sclerosus Et Atrophicus.

Immunogen :

Affinity-purified secretory component from human colostrum.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Frozen): 2-8 µg/mL, Immunohistochemistry (Paraffin): Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Aliases :

AI663821; ECM1; Extracellular matrix protein 1; LOW QUALITY PROTEIN: extracellular matrix protein 1; extracellular matrix protein 1; p85; RP11-54A4.6; Secretory component p85; testicular tissue protein Li 61; URBWD

more info or order :

Invitrogen product webpage