ICAM-3 Monoclonal Antibody (MEM-04) | Invitrogen MA1-19030 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ICAM-3 Monoclonal Antibody (MEM-04)

catalog :

MA1-19030

quantity :

100 ug

price :

US 246.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MEM-04

The same clone is also sold as:

OriGene: AM26001LE-N
Exbio: 12-452-C100, 12-452-C025

reactivity :

human

application :

immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 1

Reference
Demiry xfc rek S, Saracaloglu A, Kimyon S, Mete A, Eronat O, Temiz E, et al. Increased Expressions of ICAM-2 and ICAM-3 in Pterygium. Curr Eye Res. 2019;44:645-650 pubmed publisher

product information

Product Type :

Antibody

Product Name :

ICAM-3 Monoclonal Antibody (MEM-04)

Catalog # :

MA1-19030

Quantity :

100 ug

Price :

US 246.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 1-4 ug/mL, Functional Assay: Assay-Dependent, Immunohistochemistry (Paraffin): 10 ug/mL

Species :

Human

Clone :

MEM-04

Isotype :

IgG2b, kappa

Storage :

4 C, do not freeze

Description :

CD50 (intracellular adhesion molecule 3, ICAM-3) is a transmembrane glycoprotein expressed by leukocytes, that serves as a counter-receptor for the lymphocyte function-associated antigen (LFA)-1 integrin. Besides functioning as an adhesive molecule that mediates e.g. the contact between T cells and antigen presenting cells, ICAM-3 regulates affinity of LFA-1 for ICAM-1 and induces T cell activation and proliferation. ICAM-3 plays an essential role in the initiation of the immune response both on T cells and antigen presenting cells and interacts also with CD209 (dendritic cell-specific ICAM-3-grabbing nonintegrin, DC-SIGN), a C-type lectin of dendritic cells and macrophages; this process is involved in dialogue between dendritic cells and granulocytes.

Immunogen :

Leukocytes from a patient suffering from LGL type leukemia.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1-4 ug/mL, Functional Assay: Assay-Dependent, Immunohistochemistry (Paraffin): 10 ug/mL

Aliases :

CD50; CDw50; ICAM3; ICAM-3; ICAM-R; Intercellular adhesion molecule 3; intercellular adhesion molecule-3