CD46 Monoclonal Antibody (MEM-258) | Invitrogen MA1-19018 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD46 Monoclonal Antibody (MEM-258)

catalog :

MA1-19018

quantity :

100 µg

price :

US 322.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MEM-258

reactivity :

human, bovine

application :

western blot, immunoprecipitation, flow cytometry

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 1	Nestić D, Uil T, Ma J, Roy S, Vellinga J, Baker A, et al. αvβ3 Integrin Is Required for Efficient Infection of Epithelial Cells with Human Adenovirus Type 26. J Virol. 2019;93: pubmed publisher
	Zeng H, Yuan Q, Peng F, Ma D, Lingineni A, Chee K, et al. A split and inducible adenine base editor for precise in vivo base editing. Nat Commun. 2023;14:5573 pubmed publisher
	Stepanenko A, Sosnovtseva A, Valikhov M, Chernysheva A, Cherepanov S, Yusubalieva G, et al. Superior infectivity of the fiber chimeric oncolytic adenoviruses Ad5/35 and Ad5/3 over Ad5-delta-24-RGD in primary glioma cultures. Mol Ther Oncolytics. 2022;24:230-248 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD46 Monoclonal Antibody (MEM-258)

Catalog # :

MA1-19018

Quantity :

100 µg

Price :

US 322.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Bovine, Human

Applications :

Flow Cytometry: 1 µg/mL, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Species :

Bovine, Human

Clone :

MEM-258

Isotype :

IgG1

Storage :

4° C, do not freeze

Description :

CD46 (MCP, membrane cofactor protein) is a multifunctional cell surface transmembrane protein that binds and inactivates C3b and C4b complement fragments, regulates T cell-induced inflammatory responses by either inhibiting (CD46-1 isoform) or increasing (CD46-2 isoform) the contact hypersensitivity reaction. CD46 also serves as a receptor for several human pathogens (both bacteria and viruses), and its ligation alteres T lymphocyte polarization toward antigen-presenting cells or target cells, inhibiting lymphocyte function. CD46 is a protector of placental tissue and is also expressed on the inner acrosomal membrane of spermatozoa.

Immunogen :

T cell line HPB-ALL.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1 µg/mL, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Aliases :

AHUS2; antigen identified by monoclonal antibody TRA-2-10; brain microvascular membrane cofactor; brain microvascular membrane cofactor protein CD46; Cd46; CD46 antigen, complement regulatory protein; CD46 complement regulatory protein; CD46 molecule; CD46 molecule, complement regulatory protein; CD46 splice variant; complement membrane cofactor protein; complement regulatory protein; Mcp; MCP; complement activation regulator; measles virus receptor; membrane cofactor protein; membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen); membrane cofactor protein variant 10; membrane cofactor protein variant 7; membrane cofactor protein variant 8; membrane cofactor protein variant 9; MGC26544; MIC10; soluble membrane cofactor protein variant 11; soluble membrane cofactor protein variant 12; soluble membrane cofactor protein variant 13; TLX; TRA2.10; trophoblast leucocyte common antigen; trophoblast leukocyte common antigen; trophoblast-lymphocyte cross-reactive antigen

more info or order :

Invitrogen product webpage