HLA-G Monoclonal Antibody (MEM-G/9) | Invitrogen MA1-19014 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

HLA-G Monoclonal Antibody (MEM-G/9)

catalog :

MA1-19014

quantity :

100 µg

price :

US 342.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MEM-G/9

reactivity :

human

application :

ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 6a	Kim A, Han C, Driver I, Olow A, Sewell A, Zhang Z, et al. LILRB1 Blockade Enhances Bispecific T Cell Engager Antibody-Induced Tumor Cell Killing by Effector CD8+ T Cells. J Immunol. 2019;203:1076-1087 pubmed publisher
	Celik A, Simper G, Hiemisch W, Blasczyk R, Bade Döding C. HLA-G peptide preferences change in transformed cells: impact on the binding motif. Immunogenetics. 2018;70:485-494 pubmed publisher
	Meyer N, Woidacki K, Knöfler M, Meinhardt G, Nowak D, Velicky P, et al. Chymase-producing cells of the innate immune system are required for decidual vascular remodeling and fetal growth. Sci Rep. 2017;7:45106 pubmed publisher

product information

Product Type :

Antibody

Product Name :

HLA-G Monoclonal Antibody (MEM-G/9)

Catalog # :

MA1-19014

Quantity :

100 µg

Price :

US 342.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay-dependent, Flow Cytometry: 0.3-4 µg/mL, Immunocytochemistry: 2-5 µg/mL, Immunohistochemistry (Frozen): 1-4 µg/mL, Immunoprecipitation: Assay-dependent

Species :

Human

Clone :

MEM-G/9

Isotype :

IgG1

Storage :

4° C, do not freeze

Description :

HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail. HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

Immunogen :

Recombinant human HLA-G refolded with beta-2 Microglobulin and peptide.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Flow Cytometry: 0.3-4 µg/mL, Immunocytochemistry: 2-5 µg/mL, Immunohistochemistry (Frozen): 1-4 µg/mL, Immunoprecipitation: Assay-dependent

Aliases :

acrosomal protein SP-10; Acrosomal vesicle protein 1; ACRV1; b2 microglobulin; D11S4365; DADB-15K14.8; HLA class I histocompatibility antigen, alpha chain G; HLA class I molecule; HLA G antigen; HLA-6.0; HLAG; HLA-G; HLA-G histocompatibility antigen, class I, G; LOC768350; major histocompatibility complex, class I, G; MHC class I antigen G; MHC-G; MHCIY; MHC-like class I Y; sHLA-G; Soluble HLA class I histocompatibility antigen, alpha chain G; SP-10; SPACA2; sperm protein 10

more info or order :

Invitrogen product webpage