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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD169 Monoclonal Antibody (HSn 7D2)
catalog :
MA1-16891
quantity :
100 µL
price :
US 450.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
HSn 7D2
reactivity :
human, mouse, pigs
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 4
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:500
  • immunohistochemistry; human; 1:500
  • western blot; human; 1:500; loading ...; fig s4d
Zondler L, Müller K, Khalaji S, Bliederhäuser C, Ruf W, Grozdanov V, et al. Peripheral monocytes are functionally altered and invade the CNS in ALS patients. Acta Neuropathol. 2016;132:391-411 pubmed publisher
  • immunocytochemistry; human
  • immunohistochemistry; human
Burvall K, Palmberg L, Larsson K. Organic dust-induced activation, adhesion to substrate and expression of intercellular adhesion molecules in THP-1 monocytes. Life Sci. 2007;80:1598-607 pubmed
Hartnell A, Steel J, Turley H, Jones M, Jackson D, Crocker P. Characterization of human sialoadhesin, a sialic acid binding receptor expressed by resident and inflammatory macrophage populations. Blood. 2001;97:288-96 pubmed
Steiniger B, Barth P, Herbst B, Hartnell A, Crocker P. The species-specific structure of microanatomical compartments in the human spleen: strongly sialoadhesin-positive macrophages occur in the perifollicular zone, but not in the marginal zone. Immunology. 1997;92:307-16 pubmed
product information
Product Type :
Antibody
Product Name :
CD169 Monoclonal Antibody (HSn 7D2)
Catalog # :
MA1-16891
Quantity :
100 µL
Price :
US 450.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Human, Mouse, Porcine, Virus
Applications :
ELISA: 1:100-1:2,000, Flow Cytometry: 1:10-1:1,000, Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Frozen): 1:10-1:500, Immunohistochemistry (Paraffin): 1:10-1:500, In vitro Assay: Assay-Dependent, Radioimmune assays: Assay-Dependent, Western Blot: Assay-Dependent
Species :
Human, Mouse, Porcine, Virus
Clone :
HSn 7D2
Isotype :
IgG1
Storage :
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Description :
The siglecs are a family of membrane bound lectins (of the immunoglobulin superfamily) that bind sialic acid and mediate cell-cell interactions. Family members include sialoadhesin, CD22 and CD33. Sialoadhesin is a macrophage-specific cell adhesion molecule that is expressed on activated macrophages in chronic inflammation and in tumours.
Immunogen :
Full length hSn(d1-4)Fc protein (purified) (Human).
Format :
Liquid
Applications w/Dilutions :
ELISA: 1:100-1:2,000, Flow Cytometry: 1:10-1:1,000, Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Frozen): 1:10-1:500, Immunohistochemistry (Paraffin): 1:10-1:500, In vitro Assay: Assay-Dependent, Radioimmune assays: Assay-Dependent, Western Blot: Assay-Dependent
Aliases :
Cd169; dJ1009E24.1; macrophage receptor; p210; pSn; SA; SER; sheep erythrocyte receptor; sialic acid binding Ig like lectin 1; sialic acid binding Ig-like lectin 1, sialoadhesin; Sialic acid-binding Ig-like lectin 1; sialic acid-binding immunoglobulin-like lectin 1; sialoadhesin; SIGLEC1; Siglec-1; SN
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA