This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
PCNA Monoclonal Antibody (PC10)
catalog :
MA1-16827
quantity :
100 µl
price :
US 354
clonality :
monoclonal
host :
mouse
clone name :
PC10
reactivity :
Pacific oyster, marsh frog, , Domestic guinea pig, fission yeast, budgerigar, Saccharomyces cerevisiae S288c, hamsters, human, mouse, rat, dog, chicken, pig, zebrafish , fruit fly, sheep, common platanna, rabbit
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 165
Published Application/Species/DilutionReference
  • immunohistochemistry - paraffin section; rat
Uygur R, Aktas C, Caglar V, Uygur E, Erdogan H, Ozen O. Protective effects of melatonin against arsenic-induced apoptosis and oxidative stress in rat testes. Toxicol Ind Health. 2016;32:848-59 pubmed publisher
  • immunohistochemistry - paraffin section; rat
Erboga M, Aktas C, Kurt O, Uygur R, Caglar V, Turan B, et al. Protective effects of thymoquinone on experimental testicular ischaemia-reperfusion injury: an apoptotic, proliferative and biochemical study. Andrologia. 2016;48:222-30 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:100
Ahmed H, Shousha W, Shalby A, El-Mezayen H, Ismaiel N, Mahmoud N. Curcumin: a unique antioxidant offers a multimechanistic approach for management of hepatocellular carcinoma in rat model. Tumour Biol. 2015;36:1667-78 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:150; fig 4
La Sala G, Marazziti D, Di Pietro C, Golini E, Matteoni R, Tocchini-Valentini G. Modulation of Dhh signaling and altered Sertoli cell function in mice lacking the GPR37-prosaposin receptor. FASEB J. 2015;29:2059-69 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:50
Toydemir T, Kanter M, Erboga M, Oguz S, Erenoglu C. Antioxidative, antiapoptotic, and proliferative effect of curcumin on liver regeneration after partial hepatectomy in rats. Toxicol Ind Health. 2015;31:162-72 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:300; fig 3
  • western blot; mouse; 1:1000; fig 3
Lin X, Xu W, Shao M, Fan Q, Wen G, Li C, et al. Shenling Baizhu San supresses colitis associated colorectal cancer through inhibition of epithelial-mesenchymal transition and myeloid-derived suppressor infiltration. BMC Complement Altern Med. 2015;15:126 pubmed publisher
  • immunohistochemistry - paraffin section; rat; fig 3
Yao W, Hu Q, Ma Y, Xiong W, Wu T, Cao J, et al. Human adipose-derived mesenchymal stem cells repair cisplatin-induced acute kidney injury through antiapoptotic pathways. Exp Ther Med. 2015;10:468-476 pubmed
  • immunohistochemistry - paraffin section; mouse
Kienzl-Wagner K, Moschen A, Geiger S, Bichler A, Aigner F, Brandacher G, et al. The role of lipocalin-2 in liver regeneration. Liver Int. 2015;35:1195-202 pubmed publisher
  • immunohistochemistry - paraffin section; rat; fig 2
Mahran Y, El-Demerdash E, Nada A, El-Naga R, Ali A, Abdel-Naim A. Growth Hormone Ameliorates the Radiotherapy-Induced Ovarian Follicular Loss in Rats: Impact on Oxidative Stress, Apoptosis and IGF-1/IGF-1R Axis. PLoS ONE. 2015;10:e0140055 pubmed publisher
  • immunohistochemistry; human; 1:400
Chen W, Ho C, Chang Y, Chen H, Lin C, Ling T, et al. Cancer-associated fibroblasts regulate the plasticity of lung cancer stemness via paracrine signalling. Nat Commun. 2014;5:3472 pubmed publisher
  • immunohistochemistry - paraffin section; rat
Kamel Ismail Z, Morcos M, Eldin Mohammad M, Gamal Aboulkhair A. Enhancement of Neural Stem Cells after Induction of Depression in Male Albino Rats (A histological & Immunohistochemical Study). Int J Stem Cells. 2014;7:70-8 pubmed publisher
  • western blot; human
Whittom A, Villarreal A, Soni M, Owusu-Duku B, Meshram A, Rajkowska G, et al. Markers of apoptosis induction and proliferation in the orbitofrontal cortex in alcohol dependence. Alcohol Clin Exp Res. 2014;38:2790-9 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:1000
Gonzalez-Gomez M, Meyer G. Dynamic expression of calretinin in embryonic and early fetal human cortex. Front Neuroanat. 2014;8:41 pubmed
  • immunohistochemistry - paraffin section; human; fig 1
  • immunohistochemistry - paraffin section; mouse; fig 1
Ray P, Tassi E, Liu X, Wellstein A. Role of fibroblast growth factor-binding protein in the pathogenesis of HIV-associated hemolytic uremic syndrome. Am J Physiol Regul Integr Comp Physiol. 2006;290:R105-13 pubmed
  • immunohistochemistry - paraffin section; mouse; 1:10; fig 3
Mueller A, O'rourke J, Chu P, Chu A, Dixon M, Bouley D, et al. The role of antigenic drive and tumor-infiltrating accessory cells in the pathogenesis of helicobacter-induced mucosa-associated lymphoid tissue lymphoma. Am J Pathol. 2005;167:797-812 pubmed
  • immunohistochemistry - paraffin section; mouse
Ritter C, Martin D, Lu Y, Slatopolsky E, Brown A. Reversal of secondary hyperparathyroidism by phosphate restriction restores parathyroid calcium-sensing receptor expression and function. J Bone Miner Res. 2002;17:2206-13 pubmed
  • immunohistochemistry; rat; fig 3
Said R, Nada A, El-Demerdash E. Sodium selenite improves folliculogenesis in radiation-induced ovarian failure: a mechanistic approach. PLoS ONE. 2012;7:e50928 pubmed publisher
  • immunohistochemistry - paraffin section; rat
Ritter C, Finch J, Slatopolsky E, Brown A. Parathyroid hyperplasia in uremic rats precedes down-regulation of the calcium receptor. Kidney Int. 2001;60:1737-44 pubmed
  • immunohistochemistry; human; fig 2
Zhang C, Gurevich I, Aneskievich B. Organotypic modeling of human keratinocyte response to peroxisome proliferators. Cells Tissues Organs. 2012;196:431-41 pubmed publisher
  • immunohistochemistry - paraffin section; Pacific oyster; 1:100
  • western blot; Pacific oyster; 1:500
Franco A, Jouaux A, Mathieu M, Sourdaine P, Lelong C, Kellner K, et al. Proliferating cell nuclear antigen in gonad and associated storage tissue of the Pacific oyster Crassostrea gigas: seasonal immunodetection and expression in laser microdissected tissues. Cell Tissue Res. 2010;340:201-10 pubmed publisher
  • immunocytochemistry; human
Hoek M, Stillman B. Chromatin assembly factor 1 is essential and couples chromatin assembly to DNA replication in vivo. Proc Natl Acad Sci U S A. 2003;100:12183-8 pubmed
  • immunohistochemistry - paraffin section; rat; 1:100; tbl 1
Fuller T, Rose F, Singleton K, Linde Y, Hoff U, Freise C, et al. Glutamine donor pretreatment in rat kidney transplants with severe preservation reperfusion injury. J Surg Res. 2007;140:77-83 pubmed
  • flow cytometry; human
Naora H, Gougeon M. Interleukin-15 is a potent survival factor in the prevention of spontaneous but not CD95-induced apoptosis in CD4 and CD8 T lymphocytes of HIV-infected individuals. Correlation with its ability to increase BCL-2 expression. Cell Death Differ. 1999;6:1002-11 pubmed
  • western blot; rat; 1:300; fig 4
Li R, Strykowski R, Meyer M, Mulcrone P, Krakora D, Suzuki M. Male-specific differences in proliferation, neurogenesis, and sensitivity to oxidative stress in neural progenitor cells derived from a rat model of ALS. PLoS ONE. 2012;7:e48581 pubmed publisher
  • immunoprecipitation; human; fig 3e
Klaile E, Müller M, Kannicht C, Otto W, Singer B, Reutter W, et al. The cell adhesion receptor carcinoembryonic antigen-related cell adhesion molecule 1 regulates nucleocytoplasmic trafficking of DNA polymerase delta-interacting protein 38. J Biol Chem. 2007;282:26629-40 pubmed
  • immunohistochemistry; human; 1:40; fig 1
Bar-Shira Maymon B, Yogev L, Yavetz H, Lifschitz-Mercer B, Schreiber L, Kleiman S, et al. Spermatogonial proliferation patterns in men with azoospermia of different etiologies. Fertil Steril. 2003;80:1175-80 pubmed
  • immunohistochemistry - paraffin section; pig; 2 ug/ml; fig 3
Masters R, Crean B, Yan W, Moss A, Ryan P, Wiley A, et al. Neonatal porcine endometrial development and epithelial proliferation affected by age and exposure to estrogen and relaxin. Domest Anim Endocrinol. 2007;33:335-46 pubmed
  • immunohistochemistry; mouse
Nesslein L, Melton K, Ikegami M, Na C, Wert S, Rice W, et al. Partial SP-B deficiency perturbs lung function and causes air space abnormalities. Am J Physiol Lung Cell Mol Physiol. 2005;288:L1154-61 pubmed
  • immunohistochemistry; pig; tbl 3
Bracarense A, Yamasaki L, Silva E, Oliveira R, Alfieri A. Helicobacter spp. infection induces changes in epithelial proliferation and E-cadherin expression in the gastric mucosa of pigs. J Comp Pathol. 2013;149:402-9 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 0.2 mg/ml
Kaplanoglu G, Bahcelioglu M, Gozil R, Helvacioglu F, Buru E, Tekindal M, et al. Effects of green tea and vitamin E in the testicular tissue of streptozotocin-induced diabetic rats. Saudi Med J. 2013;34:734-43 pubmed
  • immunohistochemistry - paraffin section; rabbit; fig 3
Wen Q, Jin D, Zhou C, Zhou M, Luo W, Ma L. HGF-transgenic MSCs can improve the effects of tissue self-repair in a rabbit model of traumatic osteonecrosis of the femoral head. PLoS ONE. 2012;7:e37503 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 2
Liu X, Aigner A, Wellstein A, Ray P. Up-regulation of a fibroblast growth factor binding protein in children with renal diseases. Kidney Int. 2001;59:1717-28 pubmed
  • immunohistochemistry - paraffin section; pig; 1:100; fig 4
Fu X, Fang L, Li H, Li X, Cheng B, Sheng Z. Adipose tissue extract enhances skin wound healing. Wound Repair Regen. 2007;15:540-8 pubmed
  • immunohistochemistry - paraffin section; human; 1:400; fig 1
Li M, Liu L, Wang Z, Wang L, Liu Z, Xu G, et al. Overexpression of hMSH2 and hMLH1 protein in certain gastric cancers and their surrounding mucosae. Oncol Rep. 2008;19:401-6 pubmed
  • immunoprecipitation; hamsters; fig 3
  • western blot; hamsters; fig 1
Naryzhny S, Lee H. The post-translational modifications of proliferating cell nuclear antigen: acetylation, not phosphorylation, plays an important role in the regulation of its function. J Biol Chem. 2004;279:20194-9 pubmed
  • immunohistochemistry - paraffin section; human; 1:200; fig 1
Yakirevich E, Maroun L, Cohen O, Izhak O, Rennert G, Resnick M. Apoptosis, proliferation, and Fas (APO-1, CD95)/Fas ligand expression in medullary carcinoma of the breast. J Pathol. 2000;192:166-73 pubmed
  • immunohistochemistry - paraffin section; budgerigar; 1:100
Striedter G, Charvet C. Developmental origins of species differences in telencephalon and tectum size: morphometric comparisons between a parakeet (Melopsittacus undulatus) and a quail (Colinus virgianus). J Comp Neurol. 2008;507:1663-75 pubmed publisher
  • immunohistochemistry - paraffin section; pig; 1:100
Southgate K, Mehta D, Izzat M, Newby A, Angelini G. Increased secretion of basement membrane-degrading metalloproteinases in pig saphenous vein into carotid artery interposition grafts. Arterioscler Thromb Vasc Biol. 1999;19:1640-9 pubmed
  • immunohistochemistry - paraffin section; mouse; fig 1
Craig V, Arnold I, Gerke C, Huynh M, Wündisch T, Neubauer A, et al. Gastric MALT lymphoma B cells express polyreactive, somatically mutated immunoglobulins. Blood. 2010;115:581-91 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Danielson L, Park D, Rotllan N, Chamorro-Jorganes A, Guijarro M, Fernandez-Hernando C, et al. Cardiovascular dysregulation of miR-17-92 causes a lethal hypertrophic cardiomyopathy and arrhythmogenesis. FASEB J. 2013;27:1460-7 pubmed publisher
  • immunohistochemistry - paraffin section; rat
  • western blot; rat
Dusso A, Pavlopoulos T, Naumovich L, Lu Y, Finch J, Brown A, et al. p21(WAF1) and transforming growth factor-alpha mediate dietary phosphate regulation of parathyroid cell growth. Kidney Int. 2001;59:855-65 pubmed
  • immunohistochemistry - paraffin section; human; 1:4000; fig 4
Chang K, Huang X, Medeiros L, Jones D. Germinal centre-like versus undifferentiated stromal immunophenotypes in follicular lymphoma. J Pathol. 2003;201:404-12 pubmed
  • immunohistochemistry - paraffin section; human
Hammoud Z, Badve S, Saxena R, Kesler K, Rieger K, Malkas L, et al. A novel biomarker for the detection of esophageal adenocarcinoma. J Thorac Cardiovasc Surg. 2007;133:82-7 pubmed
  • western blot; human; fig 2
Baydoun H, Pancewicz J, Bai X, Nicot C. HTLV-I p30 inhibits multiple S phase entry checkpoints, decreases cyclin E-CDK2 interactions and delays cell cycle progression. Mol Cancer. 2010;9:302 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:10; fig 1
Sayi A, Kohler E, Hitzler I, Arnold I, Schwendener R, Rehrauer H, et al. The CD4+ T cell-mediated IFN-gamma response to Helicobacter infection is essential for clearance and determines gastric cancer risk. J Immunol. 2009;182:7085-101 pubmed publisher
  • western blot; human; 1:400; fig 2
Chimploy K, Díaz G, Li Q, Carter O, Dashwood W, Mathews C, et al. E2F4 and ribonucleotide reductase mediate S-phase arrest in colon cancer cells treated with chlorophyllin. Int J Cancer. 2009;125:2086-94 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200
Pozzi A, Wary K, Giancotti F, Gardner H. Integrin alpha1beta1 mediates a unique collagen-dependent proliferation pathway in vivo. J Cell Biol. 1998;142:587-94 pubmed
  • immunohistochemistry - frozen section; zebrafish ; 1:150; fig 4
Maurer C, Schonthaler H, Mueller K, Neuhauss S. Distinct retinal deficits in a zebrafish pyruvate dehydrogenase-deficient mutant. J Neurosci. 2010;30:11962-72 pubmed publisher
  • immunocytochemistry; human
Gupta V, Bhasin S, Guo W, Singh R, Miki R, Chauhan P, et al. Effects of dihydrotestosterone on differentiation and proliferation of human mesenchymal stem cells and preadipocytes. Mol Cell Endocrinol. 2008;296:32-40 pubmed publisher
  • immunohistochemistry; human; 1:50
Cao Y, Zhang M, Wang J, Zhang W, Li G, Zhao J. Recurrent intracranial hemangiopericytoma with multiple metastases. Chin Med J (Engl). 2006;119:169-73 pubmed
Oguz S, Kanter M, Erboga M, Toydemir T, Sayhan M, Onur H. Effects of Urtica dioica on oxidative stress, proliferation and apoptosis after partial hepatectomy in rats. Toxicol Ind Health. 2015;31:475-84 pubmed publisher
Sohn W, Choi M, Yamamoto H, Lee S, Lee Y, Jung J, et al. Contribution of mesenchymal proliferation in tooth root morphogenesis. J Dent Res. 2014;93:78-83 pubmed publisher
Xu J, Nie X, Cai X, Cai C, Xu P. Tbx18 is essential for normal development of vasculature network and glomerular mesangium in the mammalian kidney. Dev Biol. 2014;391:17-31 pubmed publisher
Xiang D, Liu C, Wang M, Li J, Chen F, Yao H, et al. Non-viral FoxM1 gene delivery to hepatocytes enhances liver repopulation. Cell Death Dis. 2014;5:e1252 pubmed publisher
Abdel-Aziz A, Shouman S, El-Demerdash E, Elgendy M, Abdel-Naim A. Chloroquine synergizes sunitinib cytotoxicity via modulating autophagic, apoptotic and angiogenic machineries. Chem Biol Interact. 2014;217:28-40 pubmed publisher
Lin X, Yi Z, Diao J, Shao M, Zhao L, Cai H, et al. ShaoYao decoction ameliorates colitis-associated colorectal cancer by downregulating proinflammatory cytokines and promoting epithelial-mesenchymal transition. J Transl Med. 2014;12:105 pubmed publisher
Uygur R, Aktas C, Tulubas F, Uygur E, Kanter M, Erboga M, et al. Protective effects of fish omega-3 fatty acids on doxorubicin-induced testicular apoptosis and oxidative damage in rats. Andrologia. 2014;46:917-26 pubmed publisher
Said R, Badr A, Nada A, El-Demerdash E. Sodium selenite treatment restores long-lasting ovarian damage induced by irradiation in rats: impact on oxidative stress and apoptosis. Reprod Toxicol. 2014;43:85-93 pubmed publisher
Ganuza M, Saiz-Ladera C, Canamero M, Gomez G, Schneider R, Blasco M, et al. Genetic inactivation of Cdk7 leads to cell cycle arrest and induces premature aging due to adult stem cell exhaustion. EMBO J. 2012;31:2498-510 pubmed publisher
Serrati S, Margheri F, Chillà A, Neumann E, Müller-Ladner U, Benucci M, et al. Reduction of in vitro invasion and in vivo cartilage degradation in a SCID mouse model by loss of function of the fibrinolytic system of rheumatoid arthritis synovial fibroblasts. Arthritis Rheum. 2011;63:2584-94 pubmed publisher
Oguz S, Kanter M, Erboga M, Erenoglu C. Protective effects of thymoquinone against cholestatic oxidative stress and hepatic damage after biliary obstruction in rats. J Mol Histol. 2012;43:151-9 pubmed publisher
Hou R, Liu L, Anees S, Hiroyasu S, Sibinga N. The Fat1 cadherin integrates vascular smooth muscle cell growth and migration signals. J Cell Biol. 2006;173:417-29 pubmed
Hao Z, Yang X, Lv Y, Li S, Purbey B, Su H. Intracolonically administered adeno-associated virus-bone morphogenetic protein-7 ameliorates dextran sulphate sodium-induced acute colitis in rats. J Gene Med. 2012;14:482-90 pubmed publisher
Wang J, Liu L, Brinton R. Estradiol-17beta-induced human neural progenitor cell proliferation is mediated by an estrogen receptor beta-phosphorylated extracellularly regulated kinase pathway. Endocrinology. 2008;149:208-18 pubmed
Erdemoglu E, Guney M, Giray S, Take G, Mungan T. Effects of metformin on mammalian target of rapamycin in a mouse model of endometrial hyperplasia. Eur J Obstet Gynecol Reprod Biol. 2009;145:195-9 pubmed publisher
Kubota Y, Takanami T, Higashitani A, Horiuchi S. Localization of X-ray cross complementing gene 1 protein in the nuclear matrix is controlled by casein kinase II-dependent phosphorylation in response to oxidative damage. DNA Repair (Amst). 2009;8:953-60 pubmed publisher
Kanter M, Aktas C, Erboga M. Protective effects of quercetin against apoptosis and oxidative stress in streptozotocin-induced diabetic rat testis. Food Chem Toxicol. 2012;50:719-25 pubmed publisher
Catal T, Bolkent S. Combination of selenium and three naturally occurring antioxidants administration protects D-galactosamine-induced liver injury in rats. Biol Trace Elem Res. 2008;122:127-36 pubmed publisher
Li M, Zhang Q, Liu L, Lu W, Wei H, Li R, et al. Expression of the mismatch repair gene hMLH1 is enhanced in non-small cell lung cancer with EGFR mutations. PLoS ONE. 2013;8:e78500 pubmed publisher
Reis J, Frias C, Canto E Castro C, Botelho M, Marques A, Simões J, et al. A new piezoelectric actuator induces bone formation in vivo: a preliminary study. J Biomed Biotechnol. 2012;2012:613403 pubmed publisher
Cui L, Johkura K, Takei S, Ogiwara N, Sasaki K. Structural differentiation, proliferation, and association of human embryonic stem cell-derived cardiomyocytes in vitro and in their extracardiac tissues. J Struct Biol. 2007;158:307-17 pubmed
Marsh V, Davies E, Williams G, Clarke A. PTEN loss and KRAS activation cooperate in murine biliary tract malignancies. J Pathol. 2013;230:165-73 pubmed publisher
Sathyan K, Nalinakumari K, Kannan S. H-Ras mutation modulates the expression of major cell cycle regulatory proteins and disease prognosis in oral carcinoma. Mod Pathol. 2007;20:1141-8 pubmed
Laine H, Doetzlhofer A, Mantela J, Ylikoski J, Laiho M, Roussel M, et al. p19(Ink4d) and p21(Cip1) collaborate to maintain the postmitotic state of auditory hair cells, their codeletion leading to DNA damage and p53-mediated apoptosis. J Neurosci. 2007;27:1434-44 pubmed
Abali R, Yuksel M, Aktas C, Celik C, Guzel S, Erfan G, et al. Decreased ovarian reserve in female Sprague-Dawley rats induced by isotretinoin (retinoic acid) exposure. Reprod Biomed Online. 2013;27:184-91 pubmed publisher
Jiao K, Wang M, Niu L, Dai J, Yu S, Liu X, et al. Death and proliferation of chondrocytes in the degraded mandibular condylar cartilage of rats induced by experimentally created disordered occlusion. Apoptosis. 2009;14:22-30 pubmed publisher
Brantley-Sieders D, Dunaway C, Rao M, Short S, Hwang Y, Gao Y, et al. Angiocrine factors modulate tumor proliferation and motility through EphA2 repression of Slit2 tumor suppressor function in endothelium. Cancer Res. 2011;71:976-87 pubmed publisher
Uyanoglu M, Canbek M, Aral E, Husnu Can Baser K. Effects of carvacrol upon the liver of rats undergoing partial hepatectomy. Phytomedicine. 2008;15:226-9 pubmed
Walter I, Tschulenk W, Schabuss M, Miller I, Grillitsch B. Structure of the seminal pathway in the European chub, Leuciscus cephalus (Cyprinidae); Teleostei. J Morphol. 2005;263:375-91 pubmed
Yu C, Chen H, Lin H, Chiang C. Expression of Bak and Bak/Mcl-1 ratio can predict photodynamic therapy outcome for oral verrucous hyperplasia and leukoplakia. J Oral Pathol Med. 2013;42:257-62 pubmed publisher
Xu G, Paige J, Jaffrey S. Global analysis of lysine ubiquitination by ubiquitin remnant immunoaffinity profiling. Nat Biotechnol. 2010;28:868-73 pubmed publisher
Saito T, Iguchi A, Tabayashi K. Irradiation inhibits vascular anastomotic stenosis in a canine model. Gen Thorac Cardiovasc Surg. 2009;57:406-12 pubmed publisher
Augustin M, Salmenperä P, Harjula A, Kankuri E. Heat shock enhances troponin expression and decreases differentiation-associated caspase-3 dependence in myoblasts under hypoxia. J Surg Res. 2010;161:62-8 pubmed publisher
Tataroglu C, Karabacak T, Apa D. Beta-catenin and CD44 expression in keratoacanthoma and squamous cell carcinoma of the skin. Tumori. 2007;93:284-9 pubmed
Peura M, Kaartinen I, Suomela S, Hukkanen M, Bizik J, Harjula A, et al. Improved skin wound epithelialization by topical delivery of soluble factors from fibroblast aggregates. Burns. 2012;38:541-50 pubmed publisher
Niederreiter L, Fritz T, Adolph T, Krismer A, Offner F, Tschurtschenthaler M, et al. ER stress transcription factor Xbp1 suppresses intestinal tumorigenesis and directs intestinal stem cells. J Exp Med. 2013;210:2041-56 pubmed publisher
Karatug A, Sacan O, Coskun Z, Bolkent S, Yanardag R, Turk N, et al. Regulation of gene expression and biochemical changes in small intestine of newborn diabetic rats by exogenous ghrelin. Peptides. 2012;33:101-8 pubmed publisher
Li C, Cheng Y, Liao P, Kang J. Translocation of p53 to mitochondria is regulated by its lipid binding property to anionic phospholipids and it participates in cell death control. Neoplasia. 2010;12:150-60 pubmed
Fiala E, Sohn O, Wang C, Seibert E, Tsurutani J, Dennis P, et al. Induction of preneoplastic lung lesions in guinea pigs by cigarette smoke inhalation and their exacerbation by high dietary levels of vitamins C and E. Carcinogenesis. 2005;26:605-12 pubmed
Kamalov G, Varma B, Lu L, Sun Y, Weber K, Guntaka R. Expression of the multifunctional Y-box protein, YB-1, in myofibroblasts of the infarcted rat heart. Biochem Biophys Res Commun. 2005;334:239-44 pubmed
Tschen S, Dhawan S, Gurlo T, Bhushan A. Age-dependent decline in beta-cell proliferation restricts the capacity of beta-cell regeneration in mice. Diabetes. 2009;58:1312-20 pubmed publisher
Li C, Cha W, Luder H, Charles R, McMahon M, Mitsiadis T, et al. E-cadherin regulates the behavior and fate of epithelial stem cells and their progeny in the mouse incisor. Dev Biol. 2012;366:357-66 pubmed publisher
Kulac M, Aktas C, Tulubas F, Uygur R, Kanter M, Erboga M, et al. The effects of topical treatment with curcumin on burn wound healing in rats. J Mol Histol. 2013;44:83-90 pubmed publisher
Gezginci-Oktayoglu S, Basaraner H, Yanardag R, Bolkent S. The effects of combined treatment of antioxidants on the liver injury in STZ diabetic rats. Dig Dis Sci. 2009;54:538-46 pubmed publisher
Gezginci-Oktayoglu S, Bolkent S, Bayrak B, Yanardag R. Z-FA.FMK activates duodenal epithelial cell proliferation through oxidative stress, NF-kappaB and IL-1beta in D-GalN/TNF-alpha-administered mice. Cell Biol Int. 2010;34:543-52 pubmed publisher
Chen X, Ren Z, Liang W, Zha D, Liu Y, Chen C, et al. c-Abl mediates angiotensin II-induced apoptosis in podocytes. J Mol Histol. 2013;44:597-608 pubmed publisher
Kanter M, Aktas C, Erboga M. Curcumin attenuates testicular damage, apoptotic germ cell death, and oxidative stress in streptozotocin-induced diabetic rats. Mol Nutr Food Res. 2013;57:1578-85 pubmed publisher
Kwon H, Ogle L, Benitez B, Bohuslav J, Montano M, Felsher D, et al. Lethal cutaneous disease in transgenic mice conditionally expressing type I human T cell leukemia virus Tax. J Biol Chem. 2005;280:35713-22 pubmed
Guijarro M, Dahiya S, Danielson L, Segura M, Vales-Lara F, Menendez S, et al. Dual Pten/Tp53 suppression promotes sarcoma progression by activating Notch signaling. Am J Pathol. 2013;182:2015-27 pubmed publisher
Qiao L, Xie L, Shi K, Zhou T, Hua Y, Liu H. Notch signaling change in pulmonary vascular remodeling in rats with pulmonary hypertension and its implication for therapeutic intervention. PLoS ONE. 2012;7:e51514 pubmed publisher
Kuriyama N, Duarte S, Hamada T, Busuttil R, Coito A. Tenascin-C: a novel mediator of hepatic ischemia and reperfusion injury. Hepatology. 2011;54:2125-36 pubmed publisher
Fay J, Kelehan P, Lambkin H, Schwartz S. Increased expression of cellular RNA-binding proteins in HPV-induced neoplasia and cervical cancer. J Med Virol. 2009;81:897-907 pubmed publisher
Park J, Ahn M, Kim T, Yoon S, Kang K, Lee J, et al. A new synthetic HDAC inhibitor, MHY218, induces apoptosis or autophagy-related cell death in tamoxifen-resistant MCF-7 breast cancer cells. Invest New Drugs. 2012;30:1887-98 pubmed publisher
Lin Y, Leu Y, Yang S, Chen H, Wang C, Pang J. Anti-psoriatic effects of indigo naturalis on the proliferation and differentiation of keratinocytes with indirubin as the active component. J Dermatol Sci. 2009;54:168-74 pubmed publisher
Heckmann L, Schlenker H, Fiedler J, Brenner R, Dauner M, Bergenthal G, et al. Human mesenchymal progenitor cell responses to a novel textured poly(L-lactide) scaffold for ligament tissue engineering. J Biomed Mater Res B Appl Biomater. 2007;81:82-90 pubmed
Hausser H, Ruegg M, Brenner R, Ksiazek I. Agrin is highly expressed by chondrocytes and is required for normal growth. Histochem Cell Biol. 2007;127:363-74 pubmed
Kawsar H, Weinberg A, Hirsch S, Venizelos A, Howell S, Jiang B, et al. Overexpression of human beta-defensin-3 in oral dysplasia: potential role in macrophage trafficking. Oral Oncol. 2009;45:696-702 pubmed publisher
Koyuturk M, Yanardag R, Bolkent S, Tunali S. The potential role of combined anti-oxidants against cadmium toxicity on liver of rats. Toxicol Ind Health. 2007;23:393-401 pubmed
Dogrul A, Colakoglu T, Kosemehmetoglu K, Birben E, Yaman E, Gedikoglu G, et al. Antiangiogenic response after 70% hepatectomy and its relationship with hepatic regeneration and angiogenesis in rats. Surgery. 2010;147:288-94 pubmed publisher
Zhang W, Cai N, Ye L, Zhang X. Transformation of human liver L-O2 cells mediated by stable HBx transfection. Acta Pharmacol Sin. 2009;30:1153-61 pubmed publisher
Zhu Y, Cui W, Cheng Y, Chang J, Chen N, Yan L. Evaluation of biodegradable paclitaxel-eluting nanofibre-covered metal stents for the treatment of benign cardia stricture in an experimental model. Br J Surg. 2013;100:784-93 pubmed publisher
Gezginci-Oktayoglu S, Tunali S, Yanardag R, Bolkent S. Effects of Z-FA.FMK on D-galactosamine/tumor necrosis factor-alpha-induced kidney injury and oxidative stress in mice : effects of Z-FA.FMK on TNF-alpha-mediated kidney injury. Mol Cell Biochem. 2008;309:9-20 pubmed
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product information
Product Type :
MA1-16827
Product Name :
PCNA Monoclonal Antibody (PC10)
Catalog # :
MA1-16827
Quantity :
100 µl
Price :
US 354
Clonality :
Monoclonal
Purity :
protein A
Host :
Mouse
Reactivity :
Chicken, Drosophila, Fish, Human, Mouse, Non-human primate, Rat, Yeast, Zebrafish
Applications :
ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation and Western Blot
Species :
Ck, Dm, Fs, Hu, Ms, Nhp, Rt, Ys, Zf
Clone :
PC10
Gene Identification :
Entrez: 373984, 37290, 5111, 18538, 25737, 852385, 30678; Uniprot: Q9DEA3, P17917, P12004, P17918, P04961, P15873, Q9PTP1
Isotype :
IgG2a, kappa
Storage :
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Description :
PCNA, also known as polymerase delta auxiliary protein, is essential for DNA replication and is involved in DNA excision and mismatch repair pathways. PCNA binds to the CDK inhibitor p21, the structure-specific endonucleases Fen1 and XPG, and DNA cytosine 5-methyltransferase (MCMT). PCNA is a potentially useful marker of cells with proliferative potential and for identifying the proliferation status of tumour tissue (i.e. relevant to prognosis).
Immunogen :
Proliferating cell nuclear antigen, (PCNA), also known as cyclin or polymerase delta accessory protein
Format :
Liquid; TBS, 0.05 % sodium azide
Applications w/Dilutions :
IF 1:1000-1:2000, IHC (F) 1:10-1:500, IHC (P) 1:500-1:1000, WB 1:2000, FACS 1:10-1:1000, ELISA Assay-Dependent, ICC 1:1000-1:2000, IP 1:100
Aliases :
Cyclin, DNA polymerase delta auxiliary protein, HGCN8729, MGC8367, polymerase delta accessory protein, Proliferating Cell Nuclear Antigen
PubMed References :
17767136, 18773217, 20955752, 22138721, 19237397, 18256689, 19097930, 19361625, 17679465, 19303259, 17640172, 21983700, 19578387, 19596613, 18571836, 18364678, 18334850, 21442622, 21547898, 20399617, 19779788, 21148069, 20460516, 19228811, 19345378, 22700475, 21707765, 18536491, 21783663, 18155124, 10079221, 11280746, 12460790, 12833516, 14999779, 15205327, 15570007, 15579485, 15758026, 16002047, 23251561, 16682528, 17032831, 17186266, 17964517, 18008146, 18227220, 18379731, 18435859, 18712602, 19052875, 19125419, 19767827, 20126473, 15731778, 20639865, 21114965, 21510892, 21898491, 22179833, 22505032, 14712430, 15007064, 20128771, 20332116, 17116689
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
www.thermofisher.com
800-678-5599
headquarters: USA