product summary
Loading...
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
FXR2 Monoclonal Antibody (1G2)
catalog :
MA1-16767
quantity :
100 µL
price :
US 420.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1G2
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, RNA immunoprecipitation
more info or order :
citations: 4
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; 1:150; loading ...; fig 6b
  • immunocytochemistry; human; 1:300; loading ...; fig 7c
  • western blot; human; 1:1000; loading ...; fig 3g
Freischmidt A, Goswami A, Limm K, Zimyanin V, Demestre M, Glaß H, et al. A serum microRNA sequence reveals fragile X protein pathology in amyotrophic lateral sclerosis. Brain. 2021;144:1214-1229 pubmed publisher
Krach F, Wheeler E, Regensburger M, Boerstler T, Wend H, Vu A, et al. Aberrant NOVA1 function disrupts alternative splicing in early stages of amyotrophic lateral sclerosis. Acta Neuropathol. 2022;: pubmed publisher
Preis P, Waldman F, Frackelton A, Saya H, Levin V. Protein-tyrosine kinase activity and pp60v-src expression in whole cells measured by flow cytometry. Cancer Res. 1988;48:4633-8 pubmed
Frackelton A, Posner M, Kannan B, Mermelstein F. Generation of monoclonal antibodies against phosphotyrosine and their use for affinity purification of phosphotyrosine-containing proteins. Methods Enzymol. 1991;201:79-92 pubmed
image
image 1 :
Invitrogen MA1-16767 image 1
Western Blot analysis of FXR2 in whole cell HeLa lysate at a concentration of 1:2500 (lane 1) and 1:500 (lane 2).
product information
Product Type :
Antibody
Product Name :
FXR2 Monoclonal Antibody (1G2)
Catalog # :
MA1-16767
Quantity :
100 µL
Price :
US 420.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Human, Mouse
Applications :
Immunocytochemistry: 2.5-5 µg/mL, Immunohistochemistry (Paraffin): 20 µg/mL, Immunoprecipitation: Assay-Dependent, RNA Immunoprecipitation: Assay-dependent, Western Blot: 1 µg/mL
Species :
Human, Mouse
Clone :
1G2
Isotype :
IgG1, kappa
Storage :
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Description :
Fragile X syndrome is caused by the absence of the fragile X mental-retardation protein (FMRP). FMRP is the archetype of a class of cytoplasmic mRNA-binding proteins that includes the fragile X-related 1 and 2 proteins (FXR1 and FXR2). The fragile X-related proteins FXR1 and FXR2 contain a functional nucleolar-targeting signal equivalent to the HIV-1 regulatory proteins.
Immunogen :
Recombinant C-terminal fragment of human FXR2 (residues 414-658).
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 2.5-5 µg/mL, Immunohistochemistry (Paraffin): 20 µg/mL, Immunoprecipitation: Assay-Dependent, RNA Immunoprecipitation: Assay-dependent, Western Blot: 1 µg/mL
Aliases :
FMR1 autosomal homolog 2; FMR1L2; fragile X mental retardation gene 2, autosomal homolog; fragile X mental retardation syndrome-related protein 2; fragile X mental retardation, autosomal homolog 2; fragile X mental retardation-related protein 2; fragile X-mental retardation 1-like 2; Fxr2; Fxr2h; FXR2P
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA