rRNA Monoclonal Antibody (Y10b) | Invitrogen MA1-16628 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

rRNA Monoclonal Antibody (Y10b)

catalog :

MA1-16628

quantity :

100 µL

price :

US 450.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

Y10b

reactivity :

rat

application :

immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; rat; 1:250	Taylor A, Wu J, Tai H, Schuman E. Axonal translation of ?-catenin regulates synaptic vesicle dynamics. J Neurosci. 2013;33:5584-9 pubmed publisher
	Deng C, Moradi M, Reinhard S, Ji C, Jablonka S, Hennlein L, et al. Dynamic remodeling of ribosomes and endoplasmic reticulum in axon terminals of motoneurons. J Cell Sci. 2021;134: pubmed publisher

image

image 1 :

Immunofluorescent staining of rRNA in vero cells.

product information

Product Type :

Antibody

Product Name :

rRNA Monoclonal Antibody (Y10b)

Catalog # :

MA1-16628

Quantity :

100 µL

Price :

US 450.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

All

Applications :

Flow Cytometry: 2.5 µg/mL, Immunocytochemistry: 1-3 µg/mL, Immunohistochemistry (Paraffin): 1:100-1:300, Immunoprecipitation: 10 µL/lysate

Species :

All

Clone :

Y10b

Isotype :

IgG3, kappa

Storage :

4° C, do not freeze

Description :

rRNA (ribosomal RNA) forms a major structural component of ribosomes which provides a mechanism for decoding mRNA information into amino acids/proteins through the process of translation. rRNA plays a key role in accurate positioning of mRNA as well as peptidyl tRNA, and also plays a structural role in peptidyl transferase activity by generating scaffolds where ribosomal proteins are assembled. rRNA is generated inside nucleolus, which is localized in nucleus of the cells and contains genes essential for encoding rRNA. Defective rRNA may implicate in certain pathologies, for example: decreased rRNA expression has been observed in subjects with myelodysplastic syndromes, and abnormal rRNA expression has also been linked to Alzheimer's disease.

Immunogen :

Whole 5.8S ribosomal RNA.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 2.5 µg/mL, Immunocytochemistry: 1-3 µg/mL, Immunohistochemistry (Paraffin): 1:100-1:300, Immunoprecipitation: 10 µL/lysate

Aliases :

ribosomal RNA; rRNA

more info or order :

Invitrogen product webpage