product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
p300 Monoclonal Antibody (RW105)
catalog :
MA1-16622
quantity :
100 µL
price :
US 456.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
RW105
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry, chromatin immunoprecipitation
more info or order :
Invitrogen product webpage
citations: 2
Published Application/Species/Sample/DilutionReference
  • chromatin immunoprecipitation; human; loading ...; fig 5e
Lin Y, Lin Y, Huang M, Kuo P, Wu C, Lee M, et al. Tumor necrosis factor-alpha inhibitors suppress CCL2 chemokine in monocytes via epigenetic modification. Mol Immunol. 2017;83:82-91 pubmed publisher
  • western blot; human
Mackeh R, Lorin S, Ratier A, Mejdoubi Charef N, Baillet A, Bruneel A, et al. Reactive oxygen species, AMP-activated protein kinase, and the transcription cofactor p300 regulate ?-tubulin acetyltransferase-1 (?TAT-1/MEC-17)-dependent microtubule hyperacetylation during cell stress. J Biol Chem. 2014;289:11816-28 pubmed publisher
product information
Product Type :
Antibody
Product Name :
p300 Monoclonal Antibody (RW105)
Catalog # :
MA1-16622
Quantity :
100 µL
Price :
US 456.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Human, Mouse, Mustelid, Non-human primate, Rat
Applications :
ChIP Assay: Assay-Dependent, Flow Cytometry: 1 µg/mL, Immunocytochemistry: 1:50-1:200, Immunomicroscopy: Assay-Dependent, Immunoprecipitation: 1:10-1:500, In vitro Assay: Assay-Dependent, Western Blot: 1:250-1:1,000
Species :
Human, Mouse, Mustelid, Non-human primate, Rat
Clone :
RW105
Isotype :
IgG1, kappa
Storage :
-20° C, Avoid Freeze/Thaw Cycles
Description :
EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. p300 is related by sequence to CPB (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CPB can stimulate transcription through activation of CREB. This EP300 activity is specifically inhibited by the adenovirus oncoprotein E1A. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF.
Immunogen :
Fusion protein containing residues 1572-2371 of human KAT3B/p300.
Format :
Liquid
Applications w/Dilutions :
ChIP Assay: Assay-Dependent, Flow Cytometry: 1 µg/mL, Immunocytochemistry: 1:50-1:200, Immunomicroscopy: Assay-Dependent, Immunoprecipitation: 1:10-1:500, In vitro Assay: Assay-Dependent, Western Blot: 1:250-1:1,000
Aliases :
A430090G16; A730011L11; E1A binding protein p300; E1A-associated protein p300; E1A-binding protein, 300kD; Ep300; Histone acetyltransferase p300; Histone butyryltransferase p300; Histone crotonyltransferase p300; KAT3B; P300; p300 HAT; Protein propionyltransferase p300; RSTS2
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA