product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
p300 Monoclonal Antibody (RW128)
catalog :
MA1-16608
quantity :
100 µL
price :
US 496.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
RW128
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry
more info or order :
citations: 4
Published Application/Species/Sample/DilutionReference
  • western blot; human
Borger D, DeCaprio J. Targeting of p300/CREB binding protein coactivators by simian virus 40 is mediated through p53. J Virol. 2006;80:4292-303 pubmed
Pao P, Patnaik D, Watson L, Gao F, Pan L, Wang J, et al. HDAC1 modulates OGG1-initiated oxidative DNA damage repair in the aging brain and Alzheimer's disease. Nat Commun. 2020;11:2484 pubmed publisher
Pujol J, Heikkila E, Savoia C, Hajibeigi A, De Marchi U, Battiprolu P, et al. Isx9 Regulates Calbindin D28K Expression in Pancreatic β Cells and Promotes β Cell Survival and Function. Int J Mol Sci. 2018;19: pubmed publisher
Kim J, Yang C, Stallcup M. Downstream signaling mechanism of the C-terminal activation domain of transcriptional coactivator CoCoA. Nucleic Acids Res. 2006;34:2736-50 pubmed
product information
Product Type :
Antibody
Product Name :
p300 Monoclonal Antibody (RW128)
Catalog # :
MA1-16608
Quantity :
100 µL
Price :
US 496.00
Clonality :
Monoclonal
Purity :
protein A
Host :
Mouse
Reactivity :
Human, Mouse, Mustelid, Non-human primate, Rat
Applications :
Flow Cytometry: 1 µg/mL, Immunocytochemistry: 2-5 µg/mL, Immunoprecipitation: 1:10-1:500, Western Blot: 1:250-1:500
Species :
Human, Mouse, Mustelid, Non-human primate, Rat
Clone :
RW128
Isotype :
IgG1, kappa
Storage :
-20° C, Avoid Freeze/Thaw Cycles
Description :
EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. p300 is related by sequence to CPB (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CPB can stimulate transcription through activation of CREB. This EP300 activity is specifically inhibited by the adenovirus oncoprotein E1A. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF.
Immunogen :
Fusion protein containing residues 1572-2371 of human p300.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1 µg/mL, Immunocytochemistry: 2-5 µg/mL, Immunoprecipitation: 1:10-1:500, Western Blot: 1:250-1:500
Aliases :
A430090G16; A730011L11; E1A binding protein p300; E1A-associated protein p300; E1A-binding protein, 300kD; Ep300; Histone acetyltransferase p300; Histone butyryltransferase p300; Histone crotonyltransferase p300; KAT3B; P300; p300 HAT; Protein propionyltransferase p300; RSTS2
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA