N-cadherin Monoclonal Antibody (13A9) | Invitrogen MA1-159 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

N-cadherin Monoclonal Antibody (13A9)

catalog :

MA1-159

quantity :

100 µg

price :

US 530

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

13A9

reactivity :

human, mouse

application :

western blot, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; mouse	Knudsen K, Sauer C, Johnson K, Wheelock M. Effect of N-cadherin misexpression by the mammary epithelium in mice. J Cell Biochem. 2005;95:1093-107 pubmed
immunohistochemistry - paraffin section; human; fig 3	Peralta Soler A, Knudsen K, Salazar H, Han A, Keshgegian A. P-cadherin expression in breast carcinoma indicates poor survival. Cancer. 1999;86:1263-72 pubmed
	Hadjisavva R, Anastasiou O, Ioannou P, Zheltkova M, Skourides P. Adherens junctions stimulate and spatially guide integrin activation and extracellular matrix deposition. Cell Rep. 2022;40:111091 pubmed publisher
	Sosnowska M, Kutwin M, Jaworski S, Strojny B, Wierzbicki M, Szczepaniak J, et al. Mechano-signalling, induced by fullerene C60 nanofilms, arrests the cell cycle in the G2/M phase and decreases proliferation of liver cancer cells. Int J Nanomedicine. 2019;14:6197-6215 pubmed publisher
	Wierzbicki M, Jaworski S, Kutwin M, Grodzik M, Strojny B, Kurantowicz N, et al. Diamond, graphite, and graphene oxide nanoparticles decrease migration and invasiveness in glioblastoma cell lines by impairing extracellular adhesion. Int J Nanomedicine. 2017;12:7241-7254 pubmed publisher

product information

Product Type :

Antibody

Product Name :

N-cadherin Monoclonal Antibody (13A9)

Catalog # :

MA1-159

Quantity :

100 µg

Price :

US 530

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 1:50-1:200, Immunoprecipitation: 2 µg, Western Blot: 1:200-1:1,000

Species :

Human, Mouse

Clone :

13A9

Isotype :

IgG1

Storage :

-20°C

Description :

N-cadherin is a 140 kDa protein belonging to a family of transmembrane molecules that mediate calcium-dependent intercellular adhesion. Cadherins are involved in controlling morphogenetic movements during development and regulate cell surface adhesion through homotypic adhesion with the same cadherin species. N-cadherin's function is dependent on its association with the actin-cytoskeleton and is mediated through interactions between the C-terminal region of N-cadherin and the cytoplasmic catenin proteins. The stability of this association is regulated by phosphorylation and dephosphorylation of beta-catenin. Further, N-cadherin is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry.

Immunogen :

MBP fusion protein containing the full cytoplasmic domain of human N-cadherin

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:50-1:200, Immunoprecipitation: 2 µg, Western Blot: 1:200-1:1,000

Aliases :

bib; cadherin 2; cadherin 2 L homeolog; cadherin 2 type 1 N-cadherin (neuronal); cadherin 2, neuronal; cadherin 2, type 1 preproprotein; cadherin 2, type 1, N-cadherin (neuronal); cadherin 2, type 1, N-cadherin (neuronal) L homeolog; cadherin 2, type 1, N-cadherin a (neuronal); Cadherin2; cadherin-2; Cadherin-2A; Cadherin-N; calcium-dependent adhesion protein, neuronal; CD325; CDH2; cdh2.L; cdh2a; cdh2-a; cdh2-b; CDHN; cdhn-a; CDw325; CDw325 antigen; cell adhesion molecule; glass onion; glo; I79_014914; labyrinth; lyr; NCAD; N-Cad; N-cadherin; N-cadherin 1; N-cadherin A; N-cadherin precursor; N-cadherin-2; neural cadherin; Neural cadherin A; neural cadherin-2; neural calcium-dependent cell adhesion molecule; neural-cadherin; pac; Parachute; unnamed protein product; wu:fb47h04; XELAEV_18031953mg; ZNCAD

more info or order :

Invitrogen product webpage