rRNA Monoclonal Antibody (Y10b) | Invitrogen MA1-13017 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

rRNA Monoclonal Antibody (Y10b)

catalog :

MA1-13017

quantity :

100 ug

price :

US 440.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

Y10b

application :

immunocytochemistry, immunoprecipitation

citations: 3

Reference
Kiparaki M, Khan C, Folgado Marco V, Chuen J, Moulos P, Baker N. The transcription factor Xrp1 orchestrates both reduced translation and cell competition upon defective ribosome assembly or function. elife. 2022;11: pubmed publisher
Alharbi A, Iyer N, Al Qaryoute A, Raman R, Burks D, Azad R, et al. Role of ribosomal RNA released from red cells in blood coagulation in zebrafish and humans. Blood Adv. 2021;5:4634-4647 pubmed publisher
Morral C, Stanisavljevic J, Hernando Momblona X, Mereu E, Álvarez Varela A, Cortina C, et al. Zonation of Ribosomal DNA Transcription Defines a Stem Cell Hierarchy in Colorectal Cancer. Cell Stem Cell. 2020;26:845-861.e12 pubmed publisher

product information

Product Type :

Antibody

Product Name :

rRNA Monoclonal Antibody (Y10b)

Catalog # :

MA1-13017

Quantity :

100 ug

Price :

US 440.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Many

Applications :

Immunocytochemistry: 2 ug/mL, Immunoprecipitation: Assay-dependent

Species :

Many

Clone :

Y10b

Isotype :

IgG3, kappa

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

rRNA (ribosomal RNA) forms a major structural component of ribosomes which provides a mechanism for decoding mRNA information into amino acids/proteins through the process of translation. rRNA plays a key role in accurate positioning of mRNA as well as peptidyl tRNA, and also plays a structural role in peptidyl transferase activity by generating scaffolds where ribosomal proteins are assembled. rRNA is generated inside nucleolus, which is localized in nucleus of the cells and contains genes essential for encoding rRNA. Defective rRNA may implicate in certain pathologies, for example: decreased rRNA expression has been observed in subjects with myelodysplastic syndromes, and abnormal rRNA expression has also been linked to Alzheimer's disease.

Immunogen :

Whole ribosomal rRNA 5.8S

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 2 ug/mL, Immunoprecipitation: Assay-dependent

Aliases :

ribosomal RNA; rRNA