Cytokeratin 5/8 Monoclonal Antibody (C50) | Invitrogen MA1-12591 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Cytokeratin 5/8 Monoclonal Antibody (C50)

catalog :

MA1-12591

quantity :

100 µg

price :

US 446.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

C50

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human	Sadlonova A, Mukherjee S, Bowe D, Gault S, Dumas N, Van Tine B, et al. Human breast fibroblasts inhibit growth of the MCF10AT xenograft model of proliferative breast disease. Am J Pathol. 2007;170:1064-76 pubmed
immunocytochemistry; human	Sadlonova A, Novak Z, Johnson M, Bowe D, Gault S, Page G, et al. Breast fibroblasts modulate epithelial cell proliferation in three-dimensional in vitro co-culture. Breast Cancer Res. 2005;7:R46-59 pubmed
	Hale L, Markert M. Corticosteroids regulate epithelial cell differentiation and Hassall body formation in the human thymus. J Immunol. 2004;172:617-24 pubmed
	Dillman J, McGary K, Schlager J. Sulfur mustard induces the formation of keratin aggregates in human epidermal keratinocytes. Toxicol Appl Pharmacol. 2003;193:228-36 pubmed

product information

Product Type :

Antibody

Product Name :

Cytokeratin 5/8 Monoclonal Antibody (C50)

Catalog # :

MA1-12591

Quantity :

100 µg

Price :

US 446.00

Clonality :

Monoclonal

Purity :

Protein A/G

Host :

Mouse

Reactivity :

Human

Applications :

Immunohistochemistry (Frozen): Assay-dependent, Western Blot: Assay-dependent

Species :

Human

Clone :

C50

Isotype :

IgG1

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between ~40 kDa and ~68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.

Immunogen :

Cytoskeleton preparation of HeLa Cells.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Frozen): Assay-dependent, Western Blot: Assay-dependent

Aliases :

3300001P10Rik; 58 kDa cytokeratin; AA960620; AL022697; AU019895; AW146334; Card2; CK5; CK-5; CK8; CK-8; CYK8; CYKER; cytokeratin 5; cytokeratin 8; cytokeratin 8 (370 AA); cytokeratin endo A; cytokeratin type II, component III; cytokeratin-5; Cytokeratin-8; cytokeratin-A; DDD; DDD1; EBS2; EndoA; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; K2C8; K5; K8; KERA; keratin 5; keratin 5 (epidermolysis bullosa simplex Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5, type II; keratin 8; keratin 8, type II; keratin complex 2, basic, gene 5; keratin complex 2, basic, gene 8; keratin, type II cytoskeletal 5; keratin, type II cytoskeletal 60 kDa, component III; Keratin, type II cytoskeletal 8; keratin, type II cytoskeletal 8-like protein; keratin-5; Keratin-8; KO; Krt-2.8; Krt2-5; Krt2-8; krt5; KRT5A; Krt8; Sak57; Tfip8; tuftelin interacting protein 8; type II cytokeratin A (no.8); type-II keratin Kb5; Type-II keratin Kb8

more info or order :

Invitrogen product webpage