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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Mu-Calpain Monoclonal Antibody (15C10)
catalog :
MA1-12434
quantity :
100 µg
price :
US 496.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
15C10
reactivity :
human, mouse, rat, bovine
application :
western blot, ELISA, immunoprecipitation
more info or order :
citations: 4
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 3a
Amici D, Pinal Fernández I, Mázala D, Lloyd T, Corse A, Christopher Stine L, et al. Calcium dysregulation, functional calpainopathy, and endoplasmic reticulum stress in sporadic inclusion body myositis. Acta Neuropathol Commun. 2017;5:24 pubmed publisher
Mahaman Y, Huang F, Wu M, Wang Y, Wei Z, Bao J, et al. Moringa Oleifera Alleviates Homocysteine-Induced Alzheimer's Disease-Like Pathology and Cognitive Impairments. J Alzheimers Dis. 2018;63:1141-1159 pubmed publisher
Elias M, Long H, Newman C, Wilson P, West A, McGill P, et al. Proteomic analysis of filaggrin deficiency identifies molecular signatures characteristic of atopic eczema. J Allergy Clin Immunol. 2017;140:1299-1309 pubmed publisher
Mikosik A, Jasiulewicz A, Daca A, Henc I, Fr x105 ckowiak J, Ruckemann Dziurdzi x144 ska K, et al. Roles of calpain-calpastatin system (CCS) in human T cell activation. Oncotarget. 2016;7:76479-76495 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Mu-Calpain Monoclonal Antibody (15C10)
Catalog # :
MA1-12434
Quantity :
100 µg
Price :
US 496.00
Clonality :
Monoclonal
Purity :
Protein A/G
Host :
Mouse
Reactivity :
Bovine, Human, Mouse, Rat
Applications :
ELISA: 0.5-1.0 µg/mL, Immunoprecipitation: 1.0-2.0 µg/mL, Western Blot: 1 µg/mL
Species :
Bovine, Human, Mouse, Rat
Clone :
15C10
Isotype :
IgG1
Storage :
-20° C, Avoid Freeze/Thaw Cycles
Description :
The calpains including Calpain 1 (CAPN1), calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. Diseases associated with CAPN1 include Spastic Paraplegia 76, Autosomal Recessive and Spasticity.
Immunogen :
Human Calpain protein purified from placenta.
Format :
Liquid
Applications w/Dilutions :
ELISA: 0.5-1.0 µg/mL, Immunoprecipitation: 1.0-2.0 µg/mL, Western Blot: 1 µg/mL
Aliases :
calcium activated neutral protease; calcium-activated neutral protease 1; calcium-activated neutral proteinase 1; calcium-dependent protease; calpain; calpain 1; calpain 1 large subunit; calpain 1, (mu/I) large subunit; calpain 1, large subunit; calpain mu-type; calpain, large polypeptide L1; calpain-1 catalytic subunit; Calpain-1 large subunit; Calpain-I; Calpain-II; CANP; CANP 1; Canp1; CANPL1; Capa1; Capa-1; Capn1; Cell proliferation-inducing gene 30 protein; cell proliferation-inducing protein 30; Cls1; I79_024883; micromolar calcium-activated neutral protease 1; micromolar calcium-activated neutral protease 1 isoform A; micromolar calcium-activated neutral protease 1 isoform B; micromolar calcium-dependent neutral protease large subunit; micromolar-calpain; mucalpain; mu-calpain; mu-calpin; muCANP; muCL; PIG30; SPG76
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA