This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Calpain S1/S2 Monoclonal Antibody (28F3)
catalog :
MA1-12433
quantity :
100 ug
price :
US 474.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
28F3

The same clone is also sold as:
reactivity :
human, bovine
application :
western blot, ELISA, immunoprecipitation
product information
Product Type :
Antibody
Product Name :
Calpain S1/S2 Monoclonal Antibody (28F3)
Catalog # :
MA1-12433
Quantity :
100 ug
Price :
US 474.00
Clonality :
Monoclonal
Purity :
Protein A/G
Host :
Mouse
Reactivity :
Bovine, Human
Applications :
ELISA: 0.5-1.0 ug/mL, Immunoprecipitation: 1-2 ug/mL, Western Blot: 0.5-1 ug/mL
Species :
Bovine, Human
Clone :
28F3
Isotype :
IgG1
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
The calpains are calcium-dependent cysteine proteases that are widely expressed in mammalian systems. Both m-calpain (calpain II) and m-calpain (calpain I) are composed of an 80 kD subunit and a 30 kD subunit. Whereas the 30 kDa subunit is shared by both enzymes, the larger catalytic subunits are different and exhibit the distinct Ca++ requirements that are suggested by their names. Whereas m-calpain requires millimolar (mM) levels of calcium, m-calpain is active at micromolar (mM) concentrations of Ca++. In addition to the ubiquitously expressed m- and m- calpains, some tissue-specific calpains have been identified. The calpains appear to serve multiple physiological roles, and ideas concerning the functions of these enzymes are in a state of rapid flux.
Immunogen :
Human Calpain protein purified from placenta.
Format :
Liquid
Applications w/Dilutions :
ELISA: 0.5-1.0 ug/mL, Immunoprecipitation: 1-2 ug/mL, Western Blot: 0.5-1 ug/mL
Aliases :
2310005G05Rik; 30K-2; calcium-activated neutral proteinase 2; Calcium-activated neutral proteinase small subunit; Calcium-dependent protease small subunit; Calcium-dependent protease small subunit 1; calcium-dependent protease small subunit 2; calcium-dependent protease, small subunit; calpain 2; calpain 2, (m/II) large subunit; calpain 2, large [catalytic] subunit; calpain 2, large subunit; calpain 4; calpain 4, small subunit (30K); calpain II regulatory subunit; calpain II regulatory subunit (EC 3.4.22.17); calpain large polypeptide L2; Calpain M-type; calpain regulatory subunit; Calpain small subunit 1; calpain small subunit 2; calpain, large polypeptide L2; calpain, small polypeptide; calpain, small subunit 1; calpain, small subunit 2; calpain-2 catalytic subunit; Calpain-2 large subunit; CALPAIN4; CANP; CANP 2; CANP small subunit; CANP2; CANPL2; CANPml; CANPS; Capa4; Capa-4; CAPN2; Capn4; CAPNS; CAPNS1; Capns2; CDPS; CSS1; CSS2; D7Ertd146e; M-calpain; mCANP; Millimolar-calpain
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA