RBL1 Monoclonal Antibody (KAB6) | Invitrogen MA1-12362 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

RBL1 Monoclonal Antibody (KAB6)

catalog :

MA1-12362

quantity :

100 µg

price :

US 446.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

KAB6

reactivity :

human, mouse, rat

application :

western blot

more info or order :

Invitrogen product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; human	Holy M, Brautigan D. Calyculin A from Discodermia calyx is a dual action toxin that blocks calcium influx and inhibits protein Ser/Thr phosphatases. Toxins (Basel). 2012;4:940-54 pubmed publisher

product information

Product Type :

Antibody

Product Name :

RBL1 Monoclonal Antibody (KAB6)

Catalog # :

MA1-12362

Quantity :

100 µg

Price :

US 446.00

Clonality :

Monoclonal

Purity :

Protein A/G

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

Western Blot: 1:1,000

Species :

Human, Mouse, Rat

Clone :

KAB6

Isotype :

IgG1

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

RB-like 1 is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and RB-like 1 can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that RB-like 1 may also be a tumor suppressor.

Immunogen :

GST fusion protein to the N terminus of p107.

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:1,000

Aliases :

107 kDa retinoblastoma-associated protein; AW547426; CP107; DNA-binding protein RFX5; MGC40006; p107; pRb1; RB transcriptional corepressor like 1; Rbl1; Regulatory factor X 5; regulatory factor X, 5 (influences HLA class II expression); regulatory factor X5; retinoblastoma-like 1; retinoblastoma-like 1 (p107); retinoblastoma-like protein 1; RFX5

more info or order :

Invitrogen product webpage