CD8/CD28 Antibody Cocktail, FITC, PE | Invitrogen MA1-12167 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD8/CD28 Antibody Cocktail, FITC, PE

catalog :

MA1-12167

quantity :

50 Tests

price :

US 438.00

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

17D8, B-23

reactivity :

human

application :

flow cytometry

product information

Product Type :

Antibody

Product Name :

CD8/CD28 Antibody Cocktail, FITC, PE

Catalog # :

MA1-12167

Quantity :

50 Tests

Price :

US 438.00

Clonality :

Cocktail

Purity :

Protein A/G

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: Assay-dependent

Species :

Human

Clone :

17D8, B-23

Isotype :

IgG1

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

CD8 molecule is composed of two chains termed alpha and beta. CD8 is found on a T cell subset of normal cytotoxic / suppressor cells which make up approximately 20 to 35 % of human peripheral blood lymphocytes. The CD8 antigen is also detected on natural killer cells, 80% of thymocytes, on a subpopulation of 30% of peripheral blood null cells and 15 to 30% of bone marrow cells. Human CD28 antigen is a 44 kDa disulfide linked homodimeric T cell specific surface glycoprotein. It is a cell adhesion molecule of the immunoglobulin superfamily which is constitutively expressed on most peripheral blood T lymphocytes (approximately 95% of CD4+ cells and 50% of CD8+ cells). Mature thymocytes exhibit higher levels of CD28 than the immature cells. Activation of T cells results in enhanced CD28 expression. T cell activation requires two combined signals provided by antigen presenting cells.

Immunogen :

human peripheral blood T lymphocytes and HPB-ALL T-cell line

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-dependent

Aliases :

CD28; CD28 antigen; CD28 molecule; CD8; CD8 antigen, alpha polypeptide (p32); CD8 antigen, beta polypeptide 1 (p37); CD8A; CD8a molecule; CD8alpha; CD8b; CD8b molecule; CD8B1; CD8beta; LEU2; Leu-2; Leu2 T-lymphocyte antigen; LY3; LYT3; MAL; MGC138290; OKT8 T-cell antigen; p32; P37; T cell co-receptor; T lymphocyte surface glycoprotein beta chain; T8 T-cell antigen; T-cell antigen Leu2; T-cell surface glycoprotein CD8 alpha chain; T-cell surface glycoprotein CD8 beta chain; T-cell-specific surface glycoprotein CD28; T-lymphocyte differentiation antigen T8/Leu-2; Tp44