product summary
Loading...
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
beta-3 Tubulin Monoclonal Antibody (2G10)
catalog :
MA1-118
quantity :
100 µg
price :
US 516.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2G10
reactivity :
Chinese hamsters, human, mouse, rat, bovine, pigs , domestic rabbit
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 22
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; mouse; 1:2000; loading ...; fig 3g
  • immunohistochemistry - frozen section; human; 1:2000; loading ...; fig 4f
Ballabio C, Anderle M, Gianesello M, Lago C, Miele E, Cardano M, et al. Modeling medulloblastoma in vivo and with human cerebellar organoids. Nat Commun. 2020;11:583 pubmed publisher
  • immunohistochemistry - frozen section; domestic rabbit; 1:100; loading ...; fig 4e
Zhou C, Robert M, Kapoulea V, Lei F, Stagner A, Jakobiec F, et al. Sustained Subconjunctival Delivery of Infliximab Protects the Cornea and Retina Following Alkali Burn to the Eye. Invest Ophthalmol Vis Sci. 2017;58:96-105 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 5e
Abe S, Yamaguchi S, Sato Y, Harada K. Sphere-Derived Multipotent Progenitor Cells Obtained From Human Oral Mucosa Are Enriched in Neural Crest Cells. Stem Cells Transl Med. 2016;5:117-28 pubmed publisher
Gouveia Roque C, Chung K, McCurdy E, Jagannathan R, Randolph L, Herline Killian K, et al. CREB3L2-ATF4 heterodimerization defines a transcriptional hub of Alzheimer's disease gene expression linked to neuropathology. Sci Adv. 2023;9:eadd2671 pubmed publisher
Cruz E, Machado L, Zamproni L, Bim L, Ferreira P, Pinto L, et al. A Gelatin Methacrylate-Based Hydrogel as a Potential Bioink for 3D Bioprinting and Neuronal Differentiation. Pharmaceutics. 2023;15: pubmed publisher
Chen O, He Q, Han Q, Furutani K, Gu Y, Olexa M, et al. Mechanisms and treatments of neuropathic itch in a mouse model of lymphoma. J Clin Invest. 2023;133: pubmed publisher
Maisonneuve B, Libralesso L, Miny L, Batut A, Rontard J, Gleyzes M, et al. Deposition chamber technology as building blocks for a standardized brain-on-chip framework. Microsyst Nanoeng. 2022;8:86 pubmed publisher
De Lorenzi E, Franceschini D, Contardi C, Di Martino R, Seghetti F, Serra M, et al. Modulation of Amyloid β-Induced Microglia Activation and Neuronal Cell Death by Curcumin and Analogues. Int J Mol Sci. 2022;23: pubmed publisher
Ahtiainen A, Genocchi B, Tanskanen J, Barros M, Hyttinen J, Lenk K. Astrocytes Exhibit a Protective Role in Neuronal Firing Patterns under Chemically Induced Seizures in Neuron-Astrocyte Co-Cultures. Int J Mol Sci. 2021;22: pubmed publisher
Hasan M, Berdichevsky Y. Neuron and astrocyte aggregation and sorting in three-dimensional neuronal constructs. Commun Biol. 2021;4:587 pubmed publisher
de Melo G, Lazarini F, Levallois S, Hautefort C, Michel V, Larrous F, et al. COVID-19-related anosmia is associated with viral persistence and inflammation in human olfactory epithelium and brain infection in hamsters. Sci Transl Med. 2021;13: pubmed publisher
Wang Y, Chen S, Jiang Q, Deng J, Cheng F, Lin Y, et al. TFAP2C facilitates somatic cell reprogramming by inhibiting c-Myc-dependent apoptosis and promoting mesenchymal-to-epithelial transition. Cell Death Dis. 2020;11:482 pubmed publisher
Stage T, Mortensen C, Khalaf S, Steffensen V, Hammer H, Xiong C, et al. P-Glycoprotein Inhibition Exacerbates Paclitaxel Neurotoxicity in Neurons and Patients With Cancer. Clin Pharmacol Ther. 2020;108:671-680 pubmed publisher
Zhu Z, Mesci P, Bernatchez J, Gimple R, Wang X, Schäfer S, et al. Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis. Cell Stem Cell. 2020;26:187-204.e10 pubmed publisher
Gorecki A, Preskey L, Bakeberg M, Kenna J, Gildenhuys C, MacDougall G, et al. Altered Gut Microbiome in Parkinson's Disease and the Influence of Lipopolysaccharide in a Human α-Synuclein Over-Expressing Mouse Model. Front Neurosci. 2019;13:839 pubmed publisher
Miki T, Vazquez L, Yanuaria L, LOPEZ O, Garcia I, Ohashi K, et al. Induced Pluripotent Stem Cell Derivation and Ex Vivo Gene Correction Using a Mucopolysaccharidosis Type 1 Disease Mouse Model. Stem Cells Int. 2019;2019:6978303 pubmed publisher
Freitas P, Lovely A, Monaghan J. Investigating Nrg1 Signaling in the Regenerating Axolotl Spinal Cord Using Multiplexed FISH. Dev Neurobiol. 2019;79:453-467 pubmed publisher
Alhazzani A, Rajagopalan P, Albarqi Z, Devaraj A, Mohamed M, Al Hakami A, et al. Mesenchymal Stem Cells (MSCs) Coculture Protects [Ca2+]i Orchestrated Oxidant Mediated Damage in Differentiated Neurons In Vitro. Cells. 2018;7: pubmed publisher
Sartor G, Malvezzi A, Kumar A, Andrade N, Wiedner H, Vilca S, et al. Enhancement of BDNF Expression and Memory by HDAC Inhibition Requires BET Bromodomain Reader Proteins. J Neurosci. 2019;39:612-626 pubmed publisher
Gouveia Roque C, Holt C. Growth Cone Tctp Is Dynamically Regulated by Guidance Cues. Front Mol Neurosci. 2018;11:399 pubmed publisher
Isaac C, Mauborgne A, Grimaldi A, Ade K, Pohl M, Limatola C, et al. Mycolactone displays anti-inflammatory effects on the nervous system. PLoS Negl Trop Dis. 2017;11:e0006058 pubmed publisher
Lehmann S, Bourgoin Voillard S, Seve M, Rachidi W. Tubulin Beta-3 Chain as a New Candidate Protein Biomarker of Human Skin Aging: A Preliminary Study. Oxid Med Cell Longev. 2017;2017:5140360 pubmed publisher
product information
Product Type :
Antibody
Product Name :
beta-3 Tubulin Monoclonal Antibody (2G10)
Catalog # :
MA1-118
Quantity :
100 µg
Price :
US 516.00
Clonality :
Monoclonal
Purity :
protein A
Host :
Mouse
Reactivity :
Bovine, Guinea Pig, Hamster, Human, Mouse, Porcine, Rabbit, Rat
Applications :
Flow Cytometry: 1:50, Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): 1:50-1:200, Immunohistochemistry: Assay-dependent, Immunoprecipitation: 5 µg, Western Blot: 1:500-1:2,000
Species :
Bovine, Guinea Pig, Hamster, Human, Mouse, Porcine, Rabbit, Rat
Clone :
2G10
Isotype :
IgG2a
Storage :
-20°C
Description :
The betaIII-tubulin isoform is present dominantly in cells of neuronal origin and it is one of the earliest markers of neuronal differentiation. It is regarded as a specific probe for the cells of neuronal origin as well as for the tumours originating from these cells. The betaIII-tubulin is most abundant in cells of neuronal origin, but was also detected in Sertoli cells of the testis and transiently in non-neuronal embryonic tissues.
Immunogen :
A synthetic peptide corresponding to amino acids 436-450 from rat neuronal specific beta-3 tubulin.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:50, Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): 1:50-1:200, Immunohistochemistry: Assay-dependent, Immunoprecipitation: 5 µg, Western Blot: 1:500-1:2,000
Aliases :
3200002H15Rik; beta 3 tubulin; beta tubulin 3; beta-4; betaIII-tubulin; CDCBM; CDCBM1; CFEOM3; CFEOM3A; class III beta-tubulin; FEOM3; I79_000194; LOC100341581; M(beta)3; M(beta)6; mc1R; melanocortin receptor 1; Neuron specific beta III Tubulin; neuron-specific class III beta-tubulin; TUBB; Tubb3; TUBB4; tubulin beta; tubulin beta 3 class III; Tubulin beta-3; tubulin beta-3 chain; Tubulin beta-4; Tubulin beta-4 chain; tubulin beta-III; tubulin, beta 3 class III; tubulin, beta, 3; tubulin, beta, 4; Unknown (protein for MGC:134115)
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA