Phospho-CREB/ATF1 (Ser133, Ser63) Monoclonal Antibody (10E9) | Invitrogen MA1-114 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-CREB/ATF1 (Ser133, Ser63) Monoclonal Antibody (10E9)

catalog :

MA1-114

quantity :

100 ug

price :

US 662.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

antigen modification :

phosphorylated

clone name :

1.00E+10

reactivity :

human, mouse, dogs

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 1

Reference
Norris J, Hughes R. protaTETHER - a method for the incorporation of variable linkers in protein fusions reveals impacts of linker flexibility in a PKAc-GFP fusion protein. FEBS Open Bio. 2018;8:1029-1042 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Phospho-CREB/ATF1 (Ser133, Ser63) Monoclonal Antibody (10E9)

Catalog # :

MA1-114

Quantity :

100 ug

Price :

US 662.00

Clonality :

Monoclonal

Purity :

Size-exclusion chromatography

Host :

Mouse

Reactivity :

Canine, Human, Mouse

Applications :

ChIP Assay: 5 uL/10^6 cells, ELISA: 0.05 ug/mL, Flow Cytometry: 1 ug/test, Immunocytochemistry: 1:20-1:200, Immunohistochemistry (Paraffin): 1:50-1:500, Western Blot: 1:500

Species :

Canine, Human, Mouse

Clone :

1.00E+10

Isotype :

IgG1

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Cyclic AMP response element binding protein (CREB) is a basic/leucine zipper transcription factor that binds the cyclic AMP response element (CRE) and activates transcription in response to a variety of extracellular signals including neurotransmitters, hormones, membrane depolarization, and growth and neurotrophic factors. Activation of CREB is dependent upon the phosphorylation of serine 133. Phosphorylation occurs via p44/42 MAP kinase and p90RSK and also via p38 MAP kinase and MSK1. Although CREB will bind DNA independent of its phosphorylation state, only the phosphorylated form is competent as a transcription factor. CREB binding protein (CBP), a transcriptional coactivator that directly interacts with CREB, binds to CREB in the region of serine 133. CREB appears to play an important role in learning and memory.

Immunogen :

A synthetic phosphopeptide corresponding to amino acids 125-135 surrounding the Ser133 phosphorylation site of human CREB

Format :

Lyophilized

Applications w/Dilutions :

ChIP Assay: 5 uL/10^6 cells, ELISA: 0.05 ug/mL, Flow Cytometry: 1 ug/test, Immunocytochemistry: 1:20-1:200, Immunohistochemistry (Paraffin): 1:50-1:500, Western Blot: 1:500

Aliases :

2310001E10Rik; 3526402H21Rik; Activating transcription factor 1; active transcription factor CREB; ATF1; AV083133; cAMP responsive element binding protein 1; cAMP-dependent transcription factor ATF-1; cAMP-response element-binding protein-1; cAMP-responsive element-binding protein 1; Creb; CREB1; Creb-1; cyclic adenosine 3',5'-monophosphate response element-binding protein CREB; cyclic AMP-dependent transcription factor ATF-1; Cyclic AMP-responsive element-binding protein 1; EWS-ATF1; FUS/ATF-1; Protein TREB36; Ser133; TCR-ATF1; transactivator protein; TREB36