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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
PAX6 Monoclonal Antibody (13B10-1A10)
catalog :
MA1-109
quantity :
100 µg
price :
US 486
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
13B10-1A10
reactivity :
African green monkey, human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 9
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; African green monkey; 1:1000; loading ...; fig 1b
  • immunohistochemistry - frozen section; human; 1:1000; loading ...; fig 1b
Kanton S, Boyle M, He Z, Santel M, Weigert A, Sanchís Calleja F, et al. Organoid single-cell genomic atlas uncovers human-specific features of brain development. Nature. 2019;574:418-422 pubmed publisher
Schaefers C, Rothmiller S, Thiermann H, Rein T, Schmidt A. The Efficiency of Direct Maturation: the Comparison of Two hiPSC Differentiation Approaches into Motor Neurons. Stem Cells Int. 2022;2022:1320950 pubmed publisher
Tang C, Wang X, D Urso M, van der Putten C, Kurniawan N. 3D Interfacial and Spatiotemporal Regulation of Human Neuroepithelial Organoids. Adv Sci (Weinh). 2022;9:e2201106 pubmed publisher
Tomasello U, Klingler E, Niquille M, Mule N, Santinha A, de Vevey L, et al. miR-137 and miR-122, two outer subventricular zone non-coding RNAs, regulate basal progenitor expansion and neuronal differentiation. Cell Rep. 2022;38:110381 pubmed publisher
Kimura K, Koizumi T, Urasawa T, Ohta Y, Takakura D, Kawasaki N. Glycoproteomic analysis of the changes in protein N-glycosylation during neuronal differentiation in human-induced pluripotent stem cells and derived neuronal cells. Sci Rep. 2021;11:11169 pubmed publisher
Phan T, Maryniak A, Boatwright C, Lee J, Atkins A, Tijhuis A, et al. Centrosome defects cause microcephaly by activating the 53BP1-USP28-TP53 mitotic surveillance pathway. EMBO J. 2021;40:e106118 pubmed publisher
Seo H, Han H, Lee S, Hong S, Cho S, Kim S, et al. Modelling Toxoplasma gondii infection in human cerebral organoids. Emerg Microbes Infect. 2020;9:1943-1954 pubmed publisher
Long Y, Hwang T, Gooding A, Goodrich K, Rinn J, Cech T. RNA is essential for PRC2 chromatin occupancy and function in human pluripotent stem cells. Nat Genet. 2020;: pubmed publisher
Hanu C, Loeliger B, Panyutin I, Maass Moreno R, Wakim P, Pritchard W, et al. Effect of Ionizing Radiation from Computed Tomography on Differentiation of Human Embryonic Stem Cells into Neural Precursors. Int J Mol Sci. 2019;20: pubmed publisher
product information
Product Type :
Antibody
Product Name :
PAX6 Monoclonal Antibody (13B10-1A10)
Catalog # :
MA1-109
Quantity :
100 µg
Price :
US 486
Clonality :
Monoclonal
Purity :
protein A
Host :
Mouse
Reactivity :
Human, Mouse
Applications :
Flow Cytometry: 1:100, Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2,000
Species :
Human, Mouse
Clone :
13B10-1A10
Isotype :
IgG1
Storage :
-20°C
Description :
This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding either the same or different isoform have been found for this gene.
Immunogen :
Purified internal fragment of human recombinant PAX6 expressed in E. coli.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:100, Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2,000
Aliases :
1500038E17Rik; AEY11; AN; AN2; Aniridia; aniridia type II protein; D11S812E; Dey; Dickie's small eye; FVH1; Gsfaey11; Keratitis; MGC17209; MGDA; oculorhombin; paired box 6; paired box gene 6; Paired Box Gene-6; paired box homeotic gene 6; paired box homeotic gene-6; paired box protein Pax-6; Pax6; Pax-6; PAX6 protein; Sey; small eye; transcription factor; WAGR
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA