NMDAR3A/NMDAR3B Monoclonal Antibody (K35/40.1) | Invitrogen MA1-10881 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

NMDAR3A/NMDAR3B Monoclonal Antibody (K35/40.1)

catalog :

MA1-10881

quantity :

100 µg

price :

US 450.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

K35/40.1

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 6g	Perearnau A, Orlando S, Islam A, Gallastegui E, Martinez J, Jordan A, et al. p27Kip1, PCAF and PAX5 cooperate in the transcriptional regulation of specific target genes. Nucleic Acids Res. 2017;45:5086-5099 pubmed publisher
immunocytochemistry; human western blot; human	Balasuriya D, Takahashi H, Srivats S, Edwardson J. Activation-induced structural change in the GluN1/GluN3A excitatory glycine receptor. Biochem Biophys Res Commun. 2014;450:1452-7 pubmed publisher

product information

Product Type :

Antibody

Product Name :

NMDAR3A/NMDAR3B Monoclonal Antibody (K35/40.1)

Catalog # :

MA1-10881

Quantity :

100 µg

Price :

US 450.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

Western Blot: 1-10 µg/mL

Species :

Human, Mouse, Rat

Clone :

K35/40.1

Isotype :

IgG1

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

Grin3a is an NMDA (N-methyl-D-aspartate) receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Grin3a is mediated by glycine and may play a role in the development of dendritic spines. Further, Grin3a may play a role in PPP2CB-NMDAR mediated signaling mechanism. Grin3a belongs to the superfamily of glutamate-regulated ion channels, and function in physiological and pathological processes in the central nervous system. Grin3a shows greater than 90% identity to the corresponding subunit in rat. Studies in the knockout mouse deficient in Grin3a suggest that the protein may be involved in the development of synaptic elements by modulating NMDA receptor activity. Diseases associated with GRIN3A include Lingual-Facial-Buccal Dyskinesia.

Immunogen :

Fusion protein of NR3A amino acids 780-914 from the extracellular III-IV loop.

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1-10 µg/mL

Aliases :

6430537F04; A830097C19Rik; chi-1; GluN3A; GluN3B; glutamate [NMDA] receptor subunit 3A; glutamate [NMDA] receptor subunit 3B; glutamate ionotropic receptor NMDA type subunit 3A; glutamate ionotropic receptor NMDA type subunit 3B; glutamate receptor; Glutamate receptor chi-1; Glutamate receptor ionotropic, NMDA 3A; glutamate receptor ionotropic, NMDA 3B; glutamate receptor ionotropic, NMDA3A; glutamate receptor, ionotropic, NMDA3B; glutamate receptor, ionotropic, N-methyl-D-aspartate 3A; glutamate receptor, ionotropic, N-methyl-D-aspartate 3B; GRIN3A; Grin3b; KIAA1973; mKIAA1973; NMDA receptor 4; NMDA receptor subunit 3B; NMDA type glutamate receptor subunit NR3B; NMDAR3A; NMDAR3B; NMDAR-L; NMDAR-L1; N-methyl-D-aspartate receptor; N-methyl-D-aspartate receptor subtype 3A; N-methyl-D-aspartate receptor subtype 3B; N-methyl-D-aspartate receptor subunit NR3B; NR3; NR3A; NR3B; Nr4

more info or order :

Invitrogen product webpage