Vimentin Monoclonal Antibody (VI-10) | Invitrogen MA1-10459 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Vimentin Monoclonal Antibody (VI-10)

catalog :

MA1-10459

quantity :

100 ug

price :

US 453.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

VI-10

reactivity :

human, mouse, rat, chicken, pigs

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:500	Zheng Y, Thomas A, Schmidt C, Dann C. Quantitative detection of human spermatogonia for optimization of spermatogonial stem cell culture. Hum Reprod. 2014;29:2497-511 pubmed publisher
	Rivera Báez L, Lohse I, Lin E, Raghavan S, Owen S, Harouaka R, et al. Expansion of Circulating Tumor Cells from Patients with Locally Advanced Pancreatic Cancer Enable Patient Derived Xenografts and Functional Studies for Personalized Medicine. Cancers (Basel). 2020;12: pubmed publisher
	Colacino J, Azizi E, Brooks M, Harouaka R, Fouladdel S, McDermott S, et al. Heterogeneity of Human Breast Stem and Progenitor Cells as Revealed by Transcriptional Profiling. Stem Cell Reports. 2018;10:1596-1609 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Vimentin Monoclonal Antibody (VI-10)

Catalog # :

MA1-10459

Quantity :

100 ug

Price :

US 453.00

Clonality :

Monoclonal

Purity :

sequential chromatography

Host :

Mouse

Reactivity :

Chicken, Human, Mouse, Porcine, Rat

Applications :

Immunocytochemistry: Assay-dependent, Immunohistochemistry (Paraffin): 5 ug/mL, Immunoprecipitation: Assay-dependent, Western Blot: 1-2 ug/mL

Species :

Chicken, Human, Mouse, Porcine, Rat

Clone :

VI-10

Isotype :

IgM

Storage :

4 C, do not freeze

Description :

Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin. It is believed to be involved with the intracellular transport of proteins between the nucleus and plasma membrane. Unlike other IFP proteins, vimentin is expressed, along with desmin, during the early stages of cellular development. During the development process, vimentin is exchanged for new, tissue-specific IFPs. Vimentin has been implicated to be involved in the rate of steroid synthesis via its role as a storage network for steroidogenic cholesterol containing lipid droplets. Vimentin phosphorylation by a protein kinase causes the breakdown of intermediate filaments and activation of an ATP and myosin light chain dependent contractile event. This results in cytoskeletal changes that facilitate the interaction of the lipid droplets within mitochondria, and subsequent transport of cholesterol to the organelles leading to an increase in steroid synthesis.

Immunogen :

not available

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: Assay-dependent, Immunohistochemistry (Paraffin): 5 ug/mL, Immunoprecipitation: Assay-dependent, Western Blot: 1-2 ug/mL

Aliases :

cb28; class-III intermediate microfilament; CTRCT30; epididymis luminal protein 113; FLJ36605; HEL113; intermediate filament; intermediate filament protein; RP11-124N14.1; similar to vimentin; VIM; VIME; Vimentin; vimentin C-terminus

more info or order :

Invitrogen product webpage