CD45RO Monoclonal Antibody (UCHL1), FITC | Invitrogen MA1-10235 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD45RO Monoclonal Antibody (UCHL1), FITC

catalog :

MA1-10235

quantity :

100 Tests

price :

US 373.00

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

UCHL1

reactivity :

human, mouse

application :

immunohistochemistry, immunocytochemistry, flow cytometry

more info or order :

Invitrogen product webpage

citations: 10

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human	Mungan S, Karaguzel E, Turan C, Reis A. A giant primary sclerosing lipogranuloma of the scrotum. Turk Patoloji Derg. 2014;30:78-80 pubmed publisher
immunohistochemistry; mouse	Honma Y, Kawano M, Kohsaka S, Ogawa M. Axonal projections of mechanoreceptive dorsal root ganglion neurons depend on Ret. Development. 2010;137:2319-28 pubmed publisher
immunohistochemistry; human; 1:1000	Belousova I, Vanecek T, Samtsov A, Michal M, Kazakov D. A patient with clinicopathologic features of small plaque parapsoriasis presenting later with plaque-stage mycosis fungoides: report of a case and comparative retrospective study of 27 cases of "nonprogressive" small plaque parapsoriasis. J Am Acad Dermatol. 2008;59:474-82 pubmed publisher
immunohistochemistry; human; 1:1000	Kazakov D, Belousova I, Kacerovska D, Sima R, Vanecek T, Vazmitel M, et al. Hyperplasia of hair follicles and other adnexal structures in cutaneous lymphoproliferative disorders: a study of 53 cases, including so-called pseudolymphomatous folliculitis and overt lymphomas. Am J Surg Pathol. 2008;32:1468-78 pubmed publisher
flow cytometry; human; fig 2	Yates J, Whittington A, Mitchell P, Lechler R, Lightstone L, Lombardi G. Natural regulatory T cells: number and function are normal in the majority of patients with lupus nephritis. Clin Exp Immunol. 2008;153:44-55 pubmed publisher
immunocytochemistry; human; 1:2500	Carolan B, Heguy A, Harvey B, Leopold P, Ferris B, Crystal R. Up-regulation of expression of the ubiquitin carboxyl-terminal hydrolase L1 gene in human airway epithelium of cigarette smokers. Cancer Res. 2006;66:10729-40 pubmed
immunohistochemistry; human; 1:1000	Boudova L, Kazakov D, Jindra P, Sima R, Vanecek T, Kuntscher V, et al. Primary cutaneous histiocyte and neutrophil-rich CD30+ and CD56+ anaplastic large-cell lymphoma with prominent angioinvasion and nerve involvement in the forehead and scalp of an immunocompetent woman. J Cutan Pathol. 2006;33:584-9 pubmed
immunohistochemistry; human; 1:1000	Boudova L, Kazakov D, Sima R, Vanecek T, Torlakovic E, Lamovec J, et al. Cutaneous lymphoid hyperplasia and other lymphoid infiltrates of the breast nipple: a retrospective clinicopathologic study of fifty-six patients. Am J Dermatopathol. 2005;27:375-86 pubmed
flow cytometry; human	McRae B, Nagai T, Semnani R, van Seventer J, van Seventer G. Interferon-alpha and -beta inhibit the in vitro differentiation of immunocompetent human dendritic cells from CD14(+) precursors. Blood. 2000;96:210-7 pubmed
	Aki H, Tuzuner N, Ongoren S, Baslar Z, Soysal T, Ferhanoglu B, et al. T-cell-rich B-cell lymphoma: a clinicopathologic study of 21 cases and comparison with 43 cases of diffuse large B-cell lymphoma. Leuk Res. 2004;28:229-36 pubmed

product information

Product Type :

Antibody

Product Name :

CD45RO Monoclonal Antibody (UCHL1), FITC

Catalog # :

MA1-10235

Quantity :

100 Tests

Price :

US 373.00

Clonality :

Monoclonal

Purity :

Size-exclusion chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 20 uL/1x10^6 cells

Species :

Human

Clone :

UCHL1

Isotype :

IgG2a

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

CD45RO (UCHL1, ubiquitin carboxyl terminal esterase L1) is the shortest isoform of a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45 isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45RO is expressed on macrophages, CD8+ T cells, activated T cells and myeloma cells. Besides the role in immunoreceptor signaling, CD45 is important in promoting cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis.

Immunogen :

Human IL-2 dependent T cells

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 20 uL/1x10^6 cells

Aliases :

B220; Cd45; CD45 antigen; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; loc; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; PTPRC; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen

more info or order :

Invitrogen product webpage