CD34 Monoclonal Antibody (581) | Invitrogen MA1-10203 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD34 Monoclonal Antibody (581)

catalog :

MA1-10203

quantity :

100 ug

price :

US 288.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

581

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; tbl 1	Monsuur H, Weijers E, Niessen F, Gefen A, Koolwijk P, Gibbs S, et al. Extensive Characterization and Comparison of Endothelial Cells Derived from Dermis and Adipose Tissue: Potential Use in Tissue Engineering. PLoS ONE. 2016;11:e0167056 pubmed publisher
flow cytometry; human; fig 1A	Yamane H, Isozaki H, Takeyama M, Ochi N, Kudo K, Honda Y, et al. Programmed cell death protein 1 and programmed death-ligand 1 are expressed on the surface of some small-cell lung cancer lines. Am J Cancer Res. 2015;5:1553-7 pubmed
flow cytometry; human; loading ...; fig 1a	Kansy B, Dißmann P, Hemeda H, Bruderek K, Westerkamp A, Jagalski V, et al. The bidirectional tumor--mesenchymal stromal cell interaction promotes the progression of head and neck cancer. Stem Cell Res Ther. 2014;5:95 pubmed publisher
immunocytochemistry; human	Barcena A, Muench M, Kapidzic M, Gormley M, Goldfien G, Fisher S. Human placenta and chorion: potential additional sources of hematopoietic stem cells for transplantation. Transfusion. 2011;51 Suppl 4:94S-105S pubmed publisher
flow cytometry; human; fig 3	Mokry J, Soukup T, Micuda S, Karbanova J, Visek B, Brcakova E, et al. Telomere attrition occurs during ex vivo expansion of human dental pulp stem cells. J Biomed Biotechnol. 2010;2010:673513 pubmed publisher
flow cytometry; human; fig 3	Erlendsson L, Muench M, Hellman U, Hrafnkelsdóttir S, Jonsson A, Balmer Y, et al. Barley as a green factory for the production of functional Flt3 ligand. Biotechnol J. 2010;5:163-71 pubmed publisher
flow cytometry; human	Mageed A, Pietryga D, DeHeer D, West R. Isolation of large numbers of mesenchymal stem cells from the washings of bone marrow collection bags: characterization of fresh mesenchymal stem cells. Transplantation. 2007;83:1019-26 pubmed
	Shlush L, Zandi S, Mitchell A, Chen W, Brandwein J, Gupta V, et al. Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia. Nature. 2014;506:328-33 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD34 Monoclonal Antibody (581)

Catalog # :

MA1-10203

Quantity :

100 ug

Price :

US 288.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Non-human primate

Applications :

Flow Cytometry: 1-4 ug/mL, Immunohistochemistry (Frozen): Assay-Dependent

Species :

Human, Non-human primate

Clone :

581

Isotype :

IgG1, kappa

Storage :

4 C, do not freeze

Description :

CD34 is a highly glycosylated monomeric with a molecular weight range of 111-115 kDa surface protein that is present on many stem cell populations. CD34 is a stem cell marker although its expression on human hematopoietic stem cells is reversible. CD34 may serve as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions. CD34 is possibly an adhesion molecule with a putative role for mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Further, CD34 could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. CD34 is thought to have a role in presenting carbohydrate ligands to selectins. The intracellular chain of the CD34 antigen is a site of phosphorylation by activated protein kinase C suggesting a putative role in signal transduction. Diseases associated with CD34 dysfunction include dermatofibrosarcoma and neurofibroma.

Immunogen :

not available

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1-4 ug/mL, Immunohistochemistry (Frozen): Assay-Dependent

Aliases :

(E3-independent) E2 ubiquitin-conjugating enzyme R1; AU040960; CD34; CD34 antigen; CD34 molecule; CDC34; cell division cycle 34; cell division cycle 34 homolog; cluster designation 34; cluster of differentiation antigen 34; E2 ubiquitin-conjugating enzyme R1; E2-CDC34; hematopoietic progenitor cell antigen CD34; hematopoietic progenitor cell marker CD34; Mucosialin; RP11-328D5.2; sialomucin protein; type 1 transmembrane protein; UBC3; UBCH3; UBE2R1; ubiquitin carrier protein; ubiquitin conjugating enzyme E2 R1; ubiquitin-conjugating enzyme E2 R1; Ubiquitin-conjugating enzyme E2-32 kDa complementing; ubiquitin-conjugating enzyme E2-CDC34; Ubiquitin-protein ligase R1

more info or order :

Invitrogen product webpage