E-cadherin Monoclonal Antibody (67A4) | Invitrogen MA1-10192 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

E-cadherin Monoclonal Antibody (67A4)

catalog :

MA1-10192

quantity :

100 ug

price :

US 436.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

67A4

The same clone is also sold as:

Exbio: 1A-588-T100, 11-588-C100, 1F-588-T100, 1F-588-T025, 1P-588-T100, 1A-588-T025, 11-588-C025, 1P-588-T025
OriGene: AM26015AC-N, AM26015RP-N, AM26015FC-N, AM26015PU-N
Abcam: ab99885, ab128125
Novus Biologicals: NBP1-42793
BioLegend: 324129, 324113, 324115, 324106, 324101, 324125, 324114, 324116, 324121, 324105, 324112, 324107, 324108, 324110, 324104, 324127, 324118, 324120, 324122, 324103, 324102
Bio-Rad: MCA6135APC, MCA6135
Santa Cruz Biotechnology: sc-21791 HRP, sc-21791, sc-21791 AC
BD Biosciences: 563571

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section

citations: 3

Reference
Gregory K, Morin S, Kubosiak A, Ser Dolansky J, Schalet B, Jerry D, et al. The use of patient-derived breast tissue explants to study macrophage polarization and the effects of environmental chemical exposure. Immunol Cell Biol. 2020;98:883-896 pubmed publisher
Mawaribuchi S, Aiki Y, Ikeda N, Ito Y. mRNA and miRNA expression profiles in an ectoderm-biased substate of human pluripotent stem cells. Sci Rep. 2019;9:11910 pubmed publisher
Anderson D, Kaplan D, Bell K, Koutsis K, Haynes J, Mills R, et al. NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network. Nat Commun. 2018;9:1373 pubmed publisher

product information

Product Type :

Antibody

Product Name :

E-cadherin Monoclonal Antibody (67A4)

Catalog # :

MA1-10192

Quantity :

100 ug

Price :

US 436.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 1-5 ug/mL, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Frozen): 4-8 ug/mL, Immunoprecipitation: Assay-Dependent, Western Blot: Assay-Dependent

Species :

Human

Clone :

67A4

Isotype :

IgG1

Storage :

4 C, do not freeze

Description :

E-Cadherin (epithelial cadherin) is a classical cadherin from the cadherin (alcium dependent adhesion protein) superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. E-cadherin plays a central role in the growth and development of cells by controlling tissue architecture, and maintenance of tissue integrity. In humans, E-cadherin is encoded by the CDH1 gene present on chromosome 16. Studies have demonstrated that reduction and/or loss of E-cadherin expression in carcinomas correlates positively with the potential of these tumors for invasion and metastasis.

Immunogen :

T-47D cells

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1-5 ug/mL, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Frozen): 4-8 ug/mL, Immunoprecipitation: Assay-Dependent, Western Blot: Assay-Dependent

Aliases :

AA960649; ARC-1; cadherin 1; cadherin 1, E-cadherin (epithelial); cadherin 1, epithelial; cadherin 1, type 1; cadherin 1, type 1, E-cadherin (epithelial); cadherin e; cadherin-1; cadherin-E; calcium-dependent adhesion protein, epithelial; CAM 120/80; CD324; CDH1; CDHE; cell adhesion molecule; cell-CAM 120/80; ECAD; E-cad; E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3; Ecadherin; E-cadherin; E-cadherin 1; E-cadherin precursor; Epithelial cadherin; hab; half baked; LCAM; L-CAM; Um; UVO; Uvomorulin