CD154 (CD40 Ligand) Monoclonal Antibody (MR-1) | Invitrogen MA1-10108 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD154 (CD40 Ligand) Monoclonal Antibody (MR-1)

catalog :

MA1-10108

quantity :

100 ug

price :

US 292.00

clonality :

monoclonal

host :

hamsters

conjugate :

nonconjugated

clone name :

MR-1

reactivity :

mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, blocking or activating experiments

more info or order :

Invitrogen product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 6a	Ferdinand J, Richard A, Meylan F, Al Shamkhani A, Siegel R. Cleavage of TL1A Differentially Regulates Its Effects on Innate and Adaptive Immune Cells. J Immunol. 2018;200:1360-1369 pubmed publisher
flow cytometry; mouse; fig 5b	Klein J, Moses K, Zelinskyy G, Sody S, Buer J, Lang S, et al. Combined toll-like receptor 3/7/9 deficiency on host cells results in T-cell-dependent control of tumour growth. Nat Commun. 2017;8:14600 pubmed publisher
blocking or activating experiments; mouse; fig 1 western blot; mouse	Foy T, Shepherd D, Durie F, Aruffo A, Ledbetter J, Noelle R. In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. II. Prolonged suppression of the humoral immune response by an antibody to the ligand for CD40, gp39. J Exp Med. 1993;178:1567-75 pubmed
	de Vinuesa C, Cook M, Ball J, Drew M, Sunners Y, Cascalho M, et al. Germinal centers without T cells. J Exp Med. 2000;191:485-94 pubmed

product information

Product Type :

Antibody

Product Name :

CD154 (CD40 Ligand) Monoclonal Antibody (MR-1)

Catalog # :

MA1-10108

Quantity :

100 ug

Price :

US 292.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Armenian Hamster

Reactivity :

Mouse

Applications :

Flow Cytometry: 4 ug/mL, Functional Assay: Assay-dependent, Immunocytochemistry: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Immunoprecipitation: Assay-Dependent

Species :

Mouse

Clone :

MR-1

Isotype :

IgG1

Storage :

4 C, do not freeze

Description :

CD40 Ligand (CD40-L), or CD154, is a membrane glycoprotein and differentiation antigen expressed on the surface of T cells. The CD40 Ligand stimulates B cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. CD40 Ligand has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also co-stimulates proliferation of activated T cells and this is accompanied by the production of IFN-gamma, TNF-alpha, and IL-2.

Immunogen :

Activated mouse Th1 clone D1.6

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 4 ug/mL, Functional Assay: Assay-dependent, Immunocytochemistry: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Immunoprecipitation: Assay-Dependent

Aliases :

CD154; CD40 antigen ligand; CD40 ligand; CD40 ligand CD154; CD40 ligand, membrane form; CD40 ligand, soluble form; CD40L; CD40-L; Cd40lg; gp39; hCD40L; H-CD-40-L; HIGM1; IGM; IMD3; Ly62; Ly-62; M-CD-40-L; RP23-153G22.3; T-B cell-activating molecule; T-BAM; T-cell antigen Gp39; TNF-related activation protein; TNFSF5; TRAP; tumor necrosis factor (ligand) superfamily member 5; tumor necrosis factor (ligand) superfamily, member 5; tumor necrosis factor ligand superfamily member 5

more info or order :

Invitrogen product webpage