CD11b Monoclonal Antibody (M1/70) | Invitrogen MA1-10080 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD11b Monoclonal Antibody (M1/70)

catalog :

MA1-10080

quantity :

100 ug

price :

US 207.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

M1/70

reactivity :

black flying fox, human, mouse, domestic rabbit

application :

ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section, immunohistochemistry - free floating section, blocking or activating experiments, other

more info or order :

Invitrogen product webpage

citations: 294

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig e5f	Brown G, Ca xf1 ete P, Wang H, Medhavy A, Bones J, Roco J, et al. TLR7 gain-of-function genetic variation causes human lupus. Nature. 2022;605:349-356 pubmed publisher
flow cytometry; mouse; 1:500; loading ...; fig s2g, s2j	Bartsch P, Kilian C, Hellmig M, Paust H, Borchers A, Sivayoganathan A, et al. Th17 cell plasticity towards a T-bet-dependent Th1 phenotype is required for bacterial control in Staphylococcus aureus infection. PLoS Pathog. 2022;18:e1010430 pubmed publisher
flow cytometry; mouse; fig 1b	Almishri W, Swain L, D Mello C, Le T, Urbanski S, Nguyen H. ADAM Metalloproteinase Domain 17 Regulates Cholestasis-Associated Liver Injury and Sickness Behavior Development in Mice. Front Immunol. 2021;12:779119 pubmed publisher
flow cytometry; mouse; loading ...; fig 1n	Bhattacharjee O, Ayyangar U, Kurbet A, Lakshmanan V, Palakodeti D, Ginhoux F, et al. Epithelial-Macrophage Crosstalk Initiates Sterile Inflammation in Embryonic Skin. Front Immunol. 2021;12:718005 pubmed publisher
flow cytometry; mouse; loading ...; fig 6b	Droho S, Cuda C, Perlman H, Lavine J. Macrophage-derived interleukin-6 is necessary and sufficient for choroidal angiogenesis. Sci Rep. 2021;11:18084 pubmed publisher
flow cytometry; mouse; loading ...; fig s1	Hoffman R, Huang S, Chalasani G, Vallejo A. Disparate Recruitment and Retention of Plasmacytoid Dendritic Cells to The Small Intestinal Mucosa between Young and Aged Mice. Aging Dis. 2021;12:1183-1196 pubmed publisher
flow cytometry; mouse; fig 3a	Petermann M, Orfanos Z, Sellau J, Gharaibeh M, Lotter H, Fleischer B, et al. CCR2 Deficiency Impairs Ly6Clo and Ly6Chi Monocyte Responses in Orientia tsutsugamushi Infection. Front Immunol. 2021;12:670219 pubmed publisher
flow cytometry; mouse; 1:100; loading ...; fig s5	Lacy M, Burger C, Shami A, Ahmadsei M, Winkels H, Nitz K, et al. Cell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease. Nat Commun. 2021;12:3754 pubmed publisher
flow cytometry; mouse; loading ...; fig 1d, 3f	Oikonomou N, Schuijs M, Chatzigiagkos A, Androulidaki A, Aidinis V, Hammad H, et al. Airway epithelial cell necroptosis contributes to asthma exacerbation in a mouse model of house dust mite-induced allergic inflammation. Mucosal Immunol. 2021;14:1160-1171 pubmed publisher
flow cytometry; mouse; loading ...; fig s2g	Liu M, Rao H, Liu J, Li X, Feng W, Gui L, et al. The histone methyltransferase SETD2 modulates oxidative stress to attenuate experimental colitis. Redox Biol. 2021;43:102004 pubmed publisher
flow cytometry; mouse; loading ...; fig 3b	McElrath C, Espinosa V, Lin J, Peng J, Sridhar R, Dutta O, et al. Critical role of interferons in gastrointestinal injury repair. Nat Commun. 2021;12:2624 pubmed publisher
flow cytometry; mouse; 1:200; loading ...	Amoozgar Z, Kloepper J, Ren J, Tay R, Kazer S, Kiner E, et al. Targeting Treg cells with GITR activation alleviates resistance to immunotherapy in murine glioblastomas. Nat Commun. 2021;12:2582 pubmed publisher
flow cytometry; mouse; 1:200; loading ...; fig 5m	Piñeiro Hermida S, Martinez P, Blasco M. Short and dysfunctional telomeres protect from allergen-induced airway inflammation. Aging Cell. 2021;20:e13352 pubmed publisher
flow cytometry; mouse; loading ...; fig s3	Flamini S, Sergeev P, Viana de Barros Z, Mello T, Biagioli M, Paglialunga M, et al. Glucocorticoid-induced leucine zipper regulates liver fibrosis by suppressing CCL2-mediated leukocyte recruitment. Cell Death Dis. 2021;12:421 pubmed publisher
flow cytometry; mouse; loading ...; fig 3	Datta M, Staszewski O. Hdac1 and Hdac2 are essential for physiological maturation of a Cx3cr1 expressing subset of T-lymphocytes. BMC Res Notes. 2021;14:135 pubmed publisher
flow cytometry; mouse; loading ...	Jhala G, Selck C, Chee J, Kwong C, Pappas E, Thomas H, et al. Tolerance to Proinsulin-1 Reduces Autoimmune Diabetes in NOD Mice. Front Immunol. 2021;12:645817 pubmed publisher
flow cytometry; mouse; fig 2a	Petty A, Dai R, Lapalombella R, Baiocchi R, Benson D, Li Z, et al. Hedgehog-induced PD-L1 on tumor-associated macrophages is critical for suppression of tumor-infiltrating CD8+ T cell function. JCI Insight. 2021;6: pubmed publisher
flow cytometry; mouse; loading ...	Zhang Y, Liu J, Wang X, Zhang J, Xie C. Extracellular vesicle-encapsulated microRNA-23a from dorsal root ganglia neurons binds to A20 and promotes inflammatory macrophage polarization following peripheral nerve injury. Aging (Albany NY). 2021;13:6752-6764 pubmed publisher
flow cytometry; mouse	Park B, Shin M, Kim J, Park G, Ryu Y, Lee J, et al. Ectopic Expression of Human Thymosin β4 Confers Resistance to Legionella pneumophila during Pulmonary and Systemic Infection in Mice. Infect Immun. 2021;89: pubmed publisher
flow cytometry; mouse; loading ...; fig 3a	Ogura Y, Tajiri K, Murakoshi N, Xu D, Yonebayashi S, Li S, et al. Neutrophil Elastase Deficiency Ameliorates Myocardial Injury Post Myocardial Infarction in Mice. Int J Mol Sci. 2021;22: pubmed publisher
flow cytometry; mouse; 1:200; loading ...	Jensen I, Jensen S, Sjaastad F, Gibson Corley K, Dileepan T, Griffith T, et al. Sepsis impedes EAE disease development and diminishes autoantigen-specific naive CD4 T cells. elife. 2020;9: pubmed publisher
flow cytometry; mouse; loading ...	Lissner M, Cumnock K, Davis N, Vilches Moure J, Basak P, Navarrete D, et al. Metabolic profiling during malaria reveals the role of the aryl hydrocarbon receptor in regulating kidney injury. elife. 2020;9: pubmed publisher
flow cytometry; mouse	Florian M, Leins H, Gobs M, Han Y, Marka G, Soller K, et al. Inhibition of Cdc42 activity extends lifespan and decreases circulating inflammatory cytokines in aged female C57BL/6 mice. Aging Cell. 2020;:e13208 pubmed publisher
flow cytometry; mouse; loading ...; fig s6i	Pasciuto E, Burton O, Roca C, Lagou V, Rajan W, Theys T, et al. Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition. Cell. 2020;182:625-640.e24 pubmed publisher
immunohistochemistry - free floating section; mouse; 1:1000; loading ...; fig 3s2d	Burfeind K, Zhu X, Norgard M, Levasseur P, Huisman C, Buenafe A, et al. Circulating myeloid cells invade the central nervous system to mediate cachexia during pancreatic cancer. elife. 2020;9: pubmed publisher
flow cytometry; human; 1:100; loading ...; fig 7b	Gao M, Wang T, Ji L, Bai S, Tian L, Song H. Therapy With Carboplatin and Anti-PD-1 Antibodies Before Surgery Demonstrates Sustainable Anti-Tumor Effects for Secondary Cancers in Mice With Triple-Negative Breast Cancer. Front Immunol. 2020;11:366 pubmed publisher
flow cytometry; mouse; loading ...; fig 3a	Patrizz A, Doran S, Chauhan A, Ahnstedt H, Roy O Reilly M, Lai Y, et al. EMMPRIN/CD147 plays a detrimental role in clinical and experimental ischemic stroke. Aging (Albany NY). 2020;12:5121-5139 pubmed publisher
flow cytometry; mouse; loading ...; fig s1	Tizian C, Lahmann A, Hölsken O, Cosovanu C, Kofoed Branzk M, Heinrich F, et al. c-Maf restrains T-bet-driven programming of CCR6-negative group 3 innate lymphoid cells. elife. 2020;9: pubmed publisher
flow cytometry; mouse; loading ...; fig 1a	Park M, Kim H, Lee H, Zabel B, Bae Y. Novel CD11b+Gr-1+Sca-1+ myeloid cells drive mortality in bacterial infection. Sci Adv. 2020;6:eaax8820 pubmed publisher
immunohistochemistry; mouse; loading ...; fig 5, 6	Raphael I, Gomez Rivera F, Raphael R, Robinson R, Nalawade S, Forsthuber T. TNFR2 limits proinflammatory astrocyte functions during EAE induced by pathogenic DR2b-restricted T cells. JCI Insight. 2019;4: pubmed publisher
flow cytometry; mouse; loading ...; fig 1g	Park C, Kehrl J. An integrin/MFG-E8 shuttle loads HIV-1 viral-like particles onto follicular dendritic cells in mouse lymph node. elife. 2019;8: pubmed publisher
flow cytometry; mouse; 1:100; loading ...; fig e1a, e1c	Vagnozzi R, Maillet M, Sargent M, Khalil H, Johansen A, Schwanekamp J, et al. An acute immune response underlies the benefit of cardiac stem cell therapy. Nature. 2020;577:405-409 pubmed publisher
flow cytometry; mouse; 1:100; loading ...; fig 2a	Luque Martin R, Van den Bossche J, Furze R, Neele A, van der Velden S, Gijbels M, et al. Targeting Histone Deacetylases in Myeloid Cells Inhibits Their Maturation and Inflammatory Function With Limited Effects on Atherosclerosis. Front Pharmacol. 2019;10:1242 pubmed publisher
flow cytometry; mouse; loading ...; fig s3d	Leone R, Zhao L, Englert J, Sun I, Oh M, Sun I, et al. Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion. Science. 2019;366:1013-1021 pubmed publisher
flow cytometry; mouse; loading ...; fig s3h	Chu C, Murdock M, Jing D, Won T, Chung H, Kressel A, et al. The microbiota regulate neuronal function and fear extinction learning. Nature. 2019;574:543-548 pubmed publisher
immunohistochemistry; mouse; 1:100; loading ...; fig 4d	Stewart B, Ferdinand J, Young M, Mitchell T, Loudon K, Riding A, et al. Spatiotemporal immune zonation of the human kidney. Science. 2019;365:1461-1466 pubmed publisher
flow cytometry; mouse; loading ...; fig 1b	Wirsching H, Zhang H, Szulzewsky F, Arora S, Grandi P, Cimino P, et al. Arming oHSV with ULBP3 drives abscopal immunity in lymphocyte-depleted glioblastoma. JCI Insight. 2019;4: pubmed publisher
flow cytometry; mouse; loading ...; fig ex3a	Croft A, Campos J, Jansen K, Turner J, Marshall J, Attar M, et al. Distinct fibroblast subsets drive inflammation and damage in arthritis. Nature. 2019;570:246-251 pubmed publisher
flow cytometry; mouse; 1:10; loading ...; fig s3a	Kobayakawa K, Ohkawa Y, Yoshizaki S, Tamaru T, Saito T, Kijima K, et al. Macrophage centripetal migration drives spontaneous healing process after spinal cord injury. Sci Adv. 2019;5:eaav5086 pubmed publisher
flow cytometry; mouse; loading ...; fig s1a	Atif S, Mack D, McKee A, Rangel Moreno J, Martin A, Getahun A, et al. Protective role of B cells in sterile particulate-induced lung injury. JCI Insight. 2019;5: pubmed publisher
flow cytometry; mouse; loading ...; fig 3d	Kotov J, Kotov D, Linehan J, Bardwell V, Gearhart M, Jenkins M. BCL6 corepressor contributes to Th17 cell formation by inhibiting Th17 fate suppressors. J Exp Med. 2019;216:1450-1464 pubmed publisher
flow cytometry; mouse; loading ...; fig 1e	Lu D, Liao Y, Zhu S, Chen Q, Xie D, Liao J, et al. Bone-derived Nestin-positive mesenchymal stem cells improve cardiac function via recruiting cardiac endothelial cells after myocardial infarction. Stem Cell Res Ther. 2019;10:127 pubmed publisher
flow cytometry; mouse; 1:1000; loading ...; fig 4g, e5a, e5b	Jacome Galarza C, Percin G, Muller J, Mass E, Lazarov T, Eitler J, et al. Developmental origin, functional maintenance and genetic rescue of osteoclasts. Nature. 2019;568:541-545 pubmed publisher
flow cytometry; mouse; loading ...; fig 4d	Salerno F, Guislain A, Freen van Heeren J, Nicolet B, Young H, Wolkers M. Critical role of post-transcriptional regulation for IFN-γ in tumor-infiltrating T cells. Oncoimmunology. 2019;8:e1532762 pubmed publisher
flow cytometry; mouse; 1:100; loading ...; fig 5c	Rosenzweig N, Dvir Szternfeld R, Tsitsou Kampeli A, Keren Shaul H, Ben Yehuda H, Weill Raynal P, et al. PD-1/PD-L1 checkpoint blockade harnesses monocyte-derived macrophages to combat cognitive impairment in a tauopathy mouse model. Nat Commun. 2019;10:465 pubmed publisher
flow cytometry; mouse; 500 ug/ml; loading ...; fig 5e	Jordão M, Sankowski R, Brendecke S, Sagar -, Locatelli G, Tai Y, et al. Single-cell profiling identifies myeloid cell subsets with distinct fates during neuroinflammation. Science. 2019;363: pubmed publisher
flow cytometry; mouse; loading ...; fig 4a	Lee Y, Ju J, Shon W, Oh S, Min C, Kang M, et al. Skewed Dendritic Cell Differentiation of MyD88-Deficient Donor Bone Marrow Cells, Instead of Massive Expansion as Myeloid-Derived Suppressor Cells, Aggravates GVHD. Immune Netw. 2018;18:e44 pubmed publisher
flow cytometry; mouse; loading ...; fig 1a	Düsedau H, Kleveman J, Figueiredo C, Biswas A, Steffen J, Kliche S, et al. p75NTR regulates brain mononuclear cell function and neuronal structure in Toxoplasma infection-induced neuroinflammation. Glia. 2019;67:193-211 pubmed publisher
flow cytometry; mouse; loading ...; fig s1	Kaplanov I, Carmi Y, Kornetsky R, Shemesh A, Shurin G, Shurin M, et al. Blocking IL-1β reverses the immunosuppression in mouse breast cancer and synergizes with anti-PD-1 for tumor abrogation. Proc Natl Acad Sci U S A. 2019;116:1361-1369 pubmed publisher
flow cytometry; mouse; loading ...; fig s1a	Percin G, Eitler J, Kranz A, Fu J, Pollard J, Naumann R, et al. CSF1R regulates the dendritic cell pool size in adult mice via embryo-derived tissue-resident macrophages. Nat Commun. 2018;9:5279 pubmed publisher
flow cytometry; mouse; loading ...; fig s2a	Gubernatorova E, Gorshkova E, Namakanova O, Zvartsev R, Hidalgo J, Drutskaya M, et al. Non-redundant Functions of IL-6 Produced by Macrophages and Dendritic Cells in Allergic Airway Inflammation. Front Immunol. 2018;9:2718 pubmed publisher
flow cytometry; mouse; loading ...; fig 4b, s3b	Sharma D, Malik A, Guy C, Vogel P, Kanneganti T. TNF/TNFR axis promotes pyrin inflammasome activation and distinctly modulates pyrin inflammasomopathy. J Clin Invest. 2019;129:150-162 pubmed publisher
flow cytometry; mouse; 1:100; loading ...; fig s1c	He Z, Zhang J, Huang Z, Du Q, Li N, Zhang Q, et al. Sumoylation of RORγt regulates TH17 differentiation and thymocyte development. Nat Commun. 2018;9:4870 pubmed publisher
flow cytometry; mouse; loading ...; fig 5i	Grigoryan A, Guidi N, Senger K, Liehr T, Soller K, Marka G, et al. LaminA/C regulates epigenetic and chromatin architecture changes upon aging of hematopoietic stem cells. Genome Biol. 2018;19:189 pubmed publisher
flow cytometry; mouse; loading ...; fig s3a	Jensen I, Winborn C, Fosdick M, Shao P, Tremblay M, Shan Q, et al. Polymicrobial sepsis influences NK-cell-mediated immunity by diminishing NK-cell-intrinsic receptor-mediated effector responses to viral ligands or infections. PLoS Pathog. 2018;14:e1007405 pubmed publisher
flow cytometry; mouse; loading ...; fig s1	Bhagwandin C, Ashbeck E, Whalen M, Bandola Simon J, Roche P, Szajman A, et al. The E3 ubiquitin ligase MARCH1 regulates glucose-tolerance and lipid storage in a sex-specific manner. PLoS ONE. 2018;13:e0204898 pubmed publisher
flow cytometry; mouse; loading ...; fig 2	Zhou J, Li J, Yu Y, Liu Y, Li H, Liu Y, et al. Mannan-binding lectin deficiency exacerbates sterile liver injury in mice through enhancing hepatic neutrophil recruitment. J Leukoc Biol. 2019;105:177-186 pubmed publisher
flow cytometry; mouse; loading ...; fig 2a	Humblet Baron S, Barber J, Roca C, Lenaerts A, Koni P, Liston A. Murine myeloproliferative disorder as a consequence of impaired collaboration between dendritic cells and CD4 T cells. Blood. 2018;: pubmed publisher
flow cytometry; mouse; loading ...; fig ev2c	Er J, Koean R, Ding J. Loss of T-bet confers survival advantage to influenza-bacterial superinfection. EMBO J. 2019;38: pubmed publisher
flow cytometry; mouse; loading ...; fig 4i	Luo H, Winkelmann E, Zhu S, Ru W, Mays E, Silvas J, et al. Peli1 facilitates virus replication and promotes neuroinflammation during West Nile virus infection. J Clin Invest. 2018;128:4980-4991 pubmed publisher
flow cytometry; mouse; loading ...; fig 1c	Chu J, Mccormick B, Mazelyte G, Michael M, Vermeren S. HoxB8 neutrophils replicate Fcγ receptor and integrin-induced neutrophil signaling and functions. J Leukoc Biol. 2019;105:93-100 pubmed publisher
flow cytometry; mouse; 1:300; loading ...; fig s7b	Zhu L, Xie X, Zhang L, Wang H, Jie Z, Zhou X, et al. TBK-binding protein 1 regulates IL-15-induced autophagy and NKT cell survival. Nat Commun. 2018;9:2812 pubmed publisher
flow cytometry; mouse; loading ...; fig 2a	Kim Y, Lee M, Gu H, Kim J, Jeong S, Yeo S, et al. HIF-1α activation in myeloid cells accelerates dextran sodium sulfate-induced colitis progression in mice. Dis Model Mech. 2018;11: pubmed publisher
flow cytometry; mouse; loading ...; fig 2b, 2c	Puchner A, Saferding V, Bonelli M, Mikami Y, Hofmann M, Brunner J, et al. Non-classical monocytes as mediators of tissue destruction in arthritis. Ann Rheum Dis. 2018;77:1490-1497 pubmed publisher
flow cytometry; human; loading ...; fig 4a	Viau A, Bienaime F, Lukas K, Todkar A, Knoll M, Yakulov T, et al. Cilia-localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney. EMBO J. 2018;37: pubmed publisher
flow cytometry; mouse; loading ...; fig 1e	Abel A, Tiwari A, Gerbec Z, Siebert J, Yang C, Schloemer N, et al. IQ Domain-Containing GTPase-Activating Protein 1 Regulates Cytoskeletal Reorganization and Facilitates NKG2D-Mediated Mechanistic Target of Rapamycin Complex 1 Activation and Cytokine Gene Translation in Natural Killer Cells. Front Immunol. 2018;9:1168 pubmed publisher
flow cytometry; mouse; 1:1000; loading ...; fig s3e	Tsiantoulas D, Sage A, Göderle L, Ozsvar Kozma M, Murphy D, Porsch F, et al. BAFF Neutralization Aggravates Atherosclerosis. Circulation. 2018;: pubmed publisher
flow cytometry; mouse; loading ...; fig 1c	Baumgartner C, Toifl S, Farlik M, Halbritter F, Scheicher R, Fischer I, et al. An ERK-Dependent Feedback Mechanism Prevents Hematopoietic Stem Cell Exhaustion. Cell Stem Cell. 2018;22:879-892.e6 pubmed publisher
flow cytometry; mouse; loading ...; fig 3a	Kanneganti A, Malireddi R, Saavedra P, Vande Walle L, Van Gorp H, Kambara H, et al. GSDMD is critical for autoinflammatory pathology in a mouse model of Familial Mediterranean Fever. J Exp Med. 2018;215:1519-1529 pubmed publisher
flow cytometry; mouse; loading ...; fig 1	Hsiao H, Fernandez R, Tanaka S, Li W, Spahn J, Chiu S, et al. Spleen-derived classical monocytes mediate lung ischemia-reperfusion injury through IL-1β. J Clin Invest. 2018;128:2833-2847 pubmed publisher
flow cytometry; mouse; loading ...; fig s2b	Thomson C, van de Pavert S, Stakenborg M, Labeeuw E, Matteoli G, Mowat A, et al. Expression of the Atypical Chemokine Receptor ACKR4 Identifies a Novel Population of Intestinal Submucosal Fibroblasts That Preferentially Expresses Endothelial Cell Regulators. J Immunol. 2018;201:215-229 pubmed publisher
flow cytometry; mouse; loading ...; fig 1e	Baba O, Horie T, Nakao T, Hakuno D, Nakashima Y, Nishi H, et al. MicroRNA 33 Regulates the Population of Peripheral Inflammatory Ly6Chigh Monocytes through Dual Pathways. Mol Cell Biol. 2018;38: pubmed publisher
flow cytometry; mouse; loading ...; fig 3e	Harker J, Wong K, Dallari S, Bao P, Dolgoter A, Jo Y, et al. Interleukin-27R Signaling Mediates Early Viral Containment and Impacts Innate and Adaptive Immunity after Chronic Lymphocytic Choriomeningitis Virus Infection. J Virol. 2018;92: pubmed publisher
flow cytometry; mouse; 1:100; loading ...; fig 2c	Mencarelli A, Khameneh H, Fric J, Vacca M, El Daker S, Janela B, et al. Calcineurin-mediated IL-2 production by CD11chighMHCII+ myeloid cells is crucial for intestinal immune homeostasis. Nat Commun. 2018;9:1102 pubmed publisher
flow cytometry; mouse; loading ...; fig 1a	Bröker K, Figge J, Magnusen A, Manz R, Köhl J, Karsten C. A Novel Role for C5a in B-1 Cell Homeostasis. Front Immunol. 2018;9:258 pubmed publisher
flow cytometry; mouse; loading ...; fig s2a	Macdougall C, Wood E, Loschko J, Scagliotti V, Cassidy F, Robinson M, et al. Visceral Adipose Tissue Immune Homeostasis Is Regulated by the Crosstalk between Adipocytes and Dendritic Cell Subsets. Cell Metab. 2018;27:588-601.e4 pubmed publisher
flow cytometry; mouse; 1:200; loading ...; fig 2b	Nair S, Huynh J, Lampropoulou V, Loginicheva E, Esaulova E, Gounder A, et al. Irg1 expression in myeloid cells prevents immunopathology during M. tuberculosis infection. J Exp Med. 2018;215:1035-1045 pubmed publisher
flow cytometry; human; 1:200; loading ...; fig s4f	Hailemichael Y, Woods A, Fu T, He Q, Nielsen M, Hasan F, et al. Cancer vaccine formulation dictates synergy with CTLA-4 and PD-L1 checkpoint blockade therapy. J Clin Invest. 2018;128:1338-1354 pubmed publisher
immunohistochemistry; mouse; loading ...; fig 6c	Westhorpe C, Norman M, Hall P, Snelgrove S, Finsterbusch M, Li A, et al. Effector CD4+ T cells recognize intravascular antigen presented by patrolling monocytes. Nat Commun. 2018;9:747 pubmed publisher
flow cytometry; mouse; loading ...; fig s1a	Perry C, Muñoz Rojas A, Meeth K, Kellman L, Amezquita R, Thakral D, et al. Myeloid-targeted immunotherapies act in synergy to induce inflammation and antitumor immunity. J Exp Med. 2018;215:877-893 pubmed publisher
flow cytometry; mouse; loading ...; fig 7a	Pitts M, Combs T, D Orazio S. Neutrophils from Both Susceptible and Resistant Mice Efficiently Kill Opsonized Listeria monocytogenes. Infect Immun. 2018;86: pubmed publisher
immunocytochemistry; mouse; fig 7d	Zhou X, Franklin R, Adler M, JACOX J, Bailis W, Shyer J, et al. Circuit Design Features of a Stable Two-Cell System. Cell. 2018;172:744-757.e17 pubmed publisher
flow cytometry; mouse; loading ...; fig 2a	Wheeler D, Sariol A, Meyerholz D, Perlman S. Microglia are required for protection against lethal coronavirus encephalitis in mice. J Clin Invest. 2018;128:931-943 pubmed publisher
flow cytometry; mouse; loading ...; fig 6c	Turner D, Goldklang M, Cvetkovski F, Paik D, Trischler J, Barahona J, et al. Biased Generation and In Situ Activation of Lung Tissue-Resident Memory CD4 T Cells in the Pathogenesis of Allergic Asthma. J Immunol. 2018;200:1561-1569 pubmed publisher
flow cytometry; mouse; loading ...; fig 2d	Guarnerio J, Mendez L, Asada N, Menon A, Fung J, Berry K, et al. A non-cell-autonomous role for Pml in the maintenance of leukemia from the niche. Nat Commun. 2018;9:66 pubmed publisher
flow cytometry; mouse; 1:200; loading ...; fig 2b, 5d, 5i	Campana L, Starkey Lewis P, Pellicoro A, Aucott R, Man J, O Duibhir E, et al. The STAT3-IL-10-IL-6 Pathway Is a Novel Regulator of Macrophage Efferocytosis and Phenotypic Conversion in Sterile Liver Injury. J Immunol. 2018;200:1169-1187 pubmed publisher
flow cytometry; mouse; loading ...; fig 3a	Wang J, Saijo K, Skola D, Jin C, Ma Q, Merkurjev D, et al. Histone demethylase LSD1 regulates hematopoietic stem cells homeostasis and protects from death by endotoxic shock. Proc Natl Acad Sci U S A. 2018;115:E244-E252 pubmed publisher
flow cytometry; mouse; 1:500; loading ...; fig 7j	Ziegler Waldkirch S, d Errico P, Sauer J, Erny D, Savanthrapadian S, Loreth D, et al. Seed-induced Aβ deposition is modulated by microglia under environmental enrichment in a mouse model of Alzheimer's disease. EMBO J. 2018;37:167-182 pubmed publisher
flow cytometry; mouse; loading ...; fig 5a	Krishnan B, Massilamany C, Basavalingappa R, Gangaplara A, Rajasekaran R, Afzal M, et al. Epitope Mapping of SERCA2a Identifies an Antigenic Determinant That Induces Mainly Atrial Myocarditis in A/J Mice. J Immunol. 2018;200:523-537 pubmed publisher
flow cytometry; mouse; loading ...; fig s3a	Medaglia C, Giladi A, Stoler Barak L, De Giovanni M, Salame T, Biram A, et al. Spatial reconstruction of immune niches by combining photoactivatable reporters and scRNA-seq. Science. 2017;358:1622-1626 pubmed publisher
flow cytometry; mouse; loading ...; fig 1e	Whitney P, Makhlouf C, MacLeod B, Ma J, Gressier E, Greyer M, et al. Effective Priming of Herpes Simplex Virus-Specific CD8+ T Cells In Vivo Does Not Require Infected Dendritic Cells. J Virol. 2018;92: pubmed publisher
flow cytometry; mouse; loading ...; fig s26b	Gopalakrishnan V, Spencer C, Nezi L, Reuben A, Andrews M, Karpinets T, et al. Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients. Science. 2018;359:97-103 pubmed publisher
flow cytometry; mouse; 1:400; loading ...	Mao A, Ishizuka I, Kasal D, Mandal M, Bendelac A. A shared Runx1-bound Zbtb16 enhancer directs innate and innate-like lymphoid lineage development. Nat Commun. 2017;8:863 pubmed publisher
flow cytometry; mouse; loading ...; fig 3d	Bern M, Beckman D, Ebihara T, Taffner S, Poursine Laurent J, White J, et al. Immunoreceptor tyrosine-based inhibitory motif-dependent functions of an MHC class I-specific NK cell receptor. Proc Natl Acad Sci U S A. 2017;114:E8440-E8447 pubmed publisher
flow cytometry; mouse; loading ...; fig 4a	Cole C, Russler Germain D, Ketkar S, Verdoni A, Smith A, Bangert C, et al. Haploinsufficiency for DNA methyltransferase 3A predisposes hematopoietic cells to myeloid malignancies. J Clin Invest. 2017;127:3657-3674 pubmed publisher
flow cytometry; mouse; loading ...; fig 1c	Mingay M, Chaturvedi A, Bilenky M, Cao Q, Jackson L, Hui T, et al. Vitamin C-induced epigenomic remodelling in IDH1 mutant acute myeloid leukaemia. Leukemia. 2018;32:11-20 pubmed publisher
flow cytometry; mouse; loading ...; fig 6a	Dunst J, Azzouz N, Liu X, Tsukita S, Seeberger P, Kamena F. Interaction between Plasmodium Glycosylphosphatidylinositol and the Host Protein Moesin Has No Implication in Malaria Pathology. Front Cell Infect Microbiol. 2017;7:183 pubmed publisher
flow cytometry; mouse; fig s6g	Hattori A, Tsunoda M, Konuma T, Kobayashi M, Nagy T, Glushka J, et al. Cancer progression by reprogrammed BCAA metabolism in myeloid leukaemia. Nature. 2017;545:500-504 pubmed publisher
flow cytometry; mouse; loading ...; fig s1b	Ebner F, Sedlyarov V, Tasciyan S, Ivin M, Kratochvill F, Gratz N, et al. The RNA-binding protein tristetraprolin schedules apoptosis of pathogen-engaged neutrophils during bacterial infection. J Clin Invest. 2017;127:2051-2065 pubmed publisher
flow cytometry; mouse; fig 3d	Bosurgi L, Cao Y, Cabeza Cabrerizo M, Tucci A, Hughes L, Kong Y, et al. Macrophage function in tissue repair and remodeling requires IL-4 or IL-13 with apoptotic cells. Science. 2017;356:1072-1076 pubmed publisher
flow cytometry; mouse; loading ...; fig s1.4b	Audzevich T, Bashford Rogers R, Mabbott N, Frampton D, Freeman T, Potocnik A, et al. Pre/pro-B cells generate macrophage populations during homeostasis and inflammation. Proc Natl Acad Sci U S A. 2017;114:E3954-E3963 pubmed publisher
flow cytometry; mouse; loading ...; fig 4b	Gittens B, Bodkin J, Nourshargh S, Perretti M, Cooper D. Galectin-3: A Positive Regulator of Leukocyte Recruitment in the Inflamed Microcirculation. J Immunol. 2017;198:4458-4469 pubmed publisher
flow cytometry; mouse; loading ...; fig e3a	Chen J, Zhong M, Guo H, Davidson D, Mishel S, Lu Y, et al. SLAMF7 is critical for phagocytosis of haematopoietic tumour cells via Mac-1 integrin. Nature. 2017;544:493-497 pubmed publisher
flow cytometry; mouse; loading ...; fig 2h	Deniset J, Surewaard B, Lee W, Kubes P. Splenic Ly6Ghigh mature and Ly6Gint immature neutrophils contribute to eradication of S. pneumoniae. J Exp Med. 2017;214:1333-1350 pubmed publisher
flow cytometry; mouse; loading ...; fig 1a	Huang Y, Rajappa P, Hu W, Hoffman C, CISSE B, Kim J, et al. A proangiogenic signaling axis in myeloid cells promotes malignant progression of glioma. J Clin Invest. 2017;127:1826-1838 pubmed publisher
flow cytometry; mouse; loading ...; fig s9f	Bouziat R, Hinterleitner R, Brown J, Stencel Baerenwald J, Ikizler M, Mayassi T, et al. Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease. Science. 2017;356:44-50 pubmed publisher
other; mouse flow cytometry; mouse; loading ...; fig 5a	Bruce D, Stefanski H, Vincent B, Dant T, Reisdorf S, Bommiasamy H, et al. Type 2 innate lymphoid cells treat and prevent acute gastrointestinal graft-versus-host disease. J Clin Invest. 2017;127:1813-1825 pubmed publisher
flow cytometry; mouse; loading ...	Schweighoffer E, Nys J, Vanes L, Smithers N, Tybulewicz V. TLR4 signals in B lymphocytes are transduced via the B cell antigen receptor and SYK. J Exp Med. 2017;214:1269-1280 pubmed publisher
flow cytometry; mouse; loading ...; fig 3a	Cockrell D, Long C, Robertson S, Shannon J, Miller H, Myers L, et al. Robust growth of avirulent phase II Coxiella burnetii in bone marrow-derived murine macrophages. PLoS ONE. 2017;12:e0173528 pubmed publisher
flow cytometry; mouse; 1:400; loading ...; fig 1a	Barthels C, Ogrinc A, Steyer V, Meier S, Simon F, Wimmer M, et al. CD40-signalling abrogates induction of RORγt+ Treg cells by intestinal CD103+ DCs and causes fatal colitis. Nat Commun. 2017;8:14715 pubmed publisher
flow cytometry; mouse; loading ...; fig 1c,d	Guidi N, Sacma M, Ständker L, Soller K, Marka G, Eiwen K, et al. Osteopontin attenuates aging-associated phenotypes of hematopoietic stem cells. EMBO J. 2017;36:840-853 pubmed publisher
flow cytometry; mouse; loading ...; fig 2c	Baranek T, Morello E, Valayer A, Aimar R, Bréa D, Henry C, et al. FHL2 Regulates Natural Killer Cell Development and Activation during Streptococcus pneumoniae Infection. Front Immunol. 2017;8:123 pubmed publisher
flow cytometry; mouse; loading ...; fig 4a	Stanley R, Piszczatowski R, Bartholdy B, Mitchell K, McKimpson W, Narayanagari S, et al. A myeloid tumor suppressor role for NOL3. J Exp Med. 2017;214:753-771 pubmed publisher
flow cytometry; mouse; loading ...; fig 2b	Lang S, Harre U, Purohit P, Dietel K, Kienhöfer D, Hahn J, et al. Neurodegeneration Enhances the Development of Arthritis. J Immunol. 2017;198:2394-2402 pubmed publisher
flow cytometry; mouse; loading ...; fig 10b	Leech J, Lacey K, Mulcahy M, Medina E, McLoughlin R. IL-10 Plays Opposing Roles during Staphylococcus aureus Systemic and Localized Infections. J Immunol. 2017;198:2352-2365 pubmed publisher
flow cytometry; mouse; loading ...; fig s2a	Vander Lugt B, Riddell J, Khan A, Hackney J, Lesch J, DeVoss J, et al. Transcriptional determinants of tolerogenic and immunogenic states during dendritic cell maturation. J Cell Biol. 2017;216:779-792 pubmed publisher
flow cytometry; mouse; fig 3	Ishiguro T, Fukawa T, Akaki K, Nagaoka K, Takeda T, Iwakura Y, et al. Absence of DCIR1 reduces the mortality rate of endotoxemic hepatitis in mice. Eur J Immunol. 2017;47:704-712 pubmed publisher
flow cytometry; mouse; loading ...; fig 5n	van Nieuwenhuijze A, Dooley J, Humblet Baron S, Sreenivasan J, Koenders M, Schlenner S, et al. Defective germinal center B-cell response and reduced arthritic pathology in microRNA-29a-deficient mice. Cell Mol Life Sci. 2017;74:2095-2106 pubmed publisher
flow cytometry; mouse; loading ...; fig s3	Edwards R, Kopp S, Ifergan I, Shui J, Kronenberg M, Miller S, et al. Murine Corneal Inflammation and Nerve Damage After Infection With HSV-1 Are Promoted by HVEM and Ameliorated by Immune-Modifying Nanoparticle Therapy. Invest Ophthalmol Vis Sci. 2017;58:282-291 pubmed publisher
flow cytometry; mouse; 1:300; fig 1e	Dror E, Dalmas E, Meier D, Wueest S, ThÃ©venet J, Thienel C, et al. Postprandial macrophage-derived IL-1Î² stimulates insulin, and both synergistically promote glucose disposal and inflammation. Nat Immunol. 2017;18:283-292 pubmed publisher
flow cytometry; mouse; loading ...; fig 1c	Shiba E, Izawa K, Kaitani A, Isobe M, Maehara A, Uchida K, et al. Ceramide-CD300f Binding Inhibits Lipopolysaccharide-induced Skin Inflammation. J Biol Chem. 2017;292:2924-2932 pubmed publisher
flow cytometry; mouse; 1:100; loading ...; fig S5	Troegeler A, Mercier I, Cougoule C, Pietretti D, Colom A, Duval C, et al. C-type lectin receptor DCIR modulates immunity to tuberculosis by sustaining type I interferon signaling in dendritic cells. Proc Natl Acad Sci U S A. 2017;114:E540-E549 pubmed publisher
flow cytometry; mouse; loading ...	de Jong R, Paulin N, Lemnitzer P, Viola J, Winter C, Ferraro B, et al. Protective Aptitude of Annexin A1 in Arterial Neointima Formation in Atherosclerosis-Prone Mice-Brief Report. Arterioscler Thromb Vasc Biol. 2017;37:312-315 pubmed publisher
flow cytometry; mouse; loading ...; fig s2	Yang J, Tanaka Y, Seay M, Li Z, Jin J, Garmire L, et al. Single cell transcriptomics reveals unanticipated features of early hematopoietic precursors. Nucleic Acids Res. 2017;45:1281-1296 pubmed publisher
flow cytometry; black flying fox; 1 ug/ml; loading ...; fig S1c	Martínez Gómez J, Periasamy P, Dutertre C, Irving A, Ng J, Crameri G, et al. Phenotypic and functional characterization of the major lymphocyte populations in the fruit-eating bat Pteropus alecto. Sci Rep. 2016;6:37796 pubmed publisher
flow cytometry; mouse; loading ...; fig 1i	Le Q, Yao W, Chen Y, Yan B, Liu C, Yuan M, et al. GRK6 regulates ROS response and maintains hematopoietic stem cell self-renewal. Cell Death Dis. 2016;7:e2478 pubmed publisher
flow cytometry; mouse; 1:100; fig s1a	Hidaka T, Ogawa E, Kobayashi E, Suzuki T, Funayama R, Nagashima T, et al. The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin. Nat Immunol. 2017;18:64-73 pubmed publisher
flow cytometry; mouse; loading ...; fig 2f	Cummings R, Barbet G, Bongers G, Hartmann B, Gettler K, Muniz L, et al. Different tissue phagocytes sample apoptotic cells to direct distinct homeostasis programs. Nature. 2016;539:565-569 pubmed publisher
flow cytometry; mouse; loading ...; fig 3D	Marichal T, Gaudenzio N, El Abbas S, Sibilano R, Zurek O, Starkl P, et al. Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis. J Clin Invest. 2016;126:4497-4515 pubmed publisher
flow cytometry; mouse; loading ...; fig s1d	Shirakawa K, Yan X, Shinmura K, Endo J, Kataoka M, Katsumata Y, et al. Obesity accelerates T cell senescence in murine visceral adipose tissue. J Clin Invest. 2016;126:4626-4639 pubmed publisher
flow cytometry; mouse; fig s3a	Laurent C, Dorothee G, Hunot S, Martin E, Monnet Y, Duchamp M, et al. Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of tauopathy. Brain. 2017;140:184-200 pubmed publisher
flow cytometry; mouse; 1:4000; loading ...; fig 1a	Hirako I, Ataide M, Faustino L, Assis P, Sorensen E, Ueta H, et al. Splenic differentiation and emergence of CCR5+CXCL9+CXCL10+ monocyte-derived dendritic cells in the brain during cerebral malaria. Nat Commun. 2016;7:13277 pubmed publisher
flow cytometry; mouse; loading ...; fig s1i	Dong L, Yu W, Zheng H, Loh M, Bunting S, Pauly M, et al. Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment. Nature. 2016;539:304-308 pubmed publisher
flow cytometry; mouse; 1:400; loading ...; fig 6c	Ulland T, Jain N, Hornick E, Elliott E, Clay G, Sadler J, et al. Nlrp12 mutation causes C57BL/6J strain-specific defect in neutrophil recruitment. Nat Commun. 2016;7:13180 pubmed publisher
flow cytometry; mouse; loading ...; fig 1a	Jiang J, Gao Q, Wang T, Lin H, Zhan Q, Chu Z, et al. MicroRNA expression profiles of granulocytic myeloid?derived suppressor cells from mice bearing Lewis lung carcinoma. Mol Med Rep. 2016;14:4567-4574 pubmed publisher
flow cytometry; mouse; loading ...	Mascarell L, Airouche S, Berjont N, Gary C, Gueguen C, Fourcade G, et al. The regulatory dendritic cell marker C1q is a potent inhibitor of allergic inflammation. Mucosal Immunol. 2017;10:695-704 pubmed publisher
flow cytometry; mouse; loading ...	Ramirez Carrozzi V, Sambandam A, Zhou M, Yan D, Kang J, Wu X, et al. Combined blockade of the IL-13 and IL-33 pathways leads to a greater inhibition of type 2 inflammation over inhibition of either pathway alone. J Allergy Clin Immunol. 2017;139:705-708.e6 pubmed publisher
flow cytometry; mouse; loading ...; fig st1	Johnston L, Hsu C, Krier Burris R, Chhiba K, Chien K, McKenzie A, et al. IL-33 Precedes IL-5 in Regulating Eosinophil Commitment and Is Required for Eosinophil Homeostasis. J Immunol. 2016;197:3445-3453 pubmed
flow cytometry; mouse; loading ...	Rothchild A, Sissons J, Shafiani S, Plaisier C, Min D, Mai D, et al. MiR-155-regulated molecular network orchestrates cell fate in the innate and adaptive immune response to Mycobacterium tuberculosis. Proc Natl Acad Sci U S A. 2016;113:E6172-E6181 pubmed
flow cytometry; mouse; loading ...; fig 1a	Takeshima T, Pop L, Laine A, Iyengar P, Vitetta E, Hannan R. Key role for neutrophils in radiation-induced antitumor immune responses: Potentiation with G-CSF. Proc Natl Acad Sci U S A. 2016;113:11300-11305 pubmed
flow cytometry; mouse; loading ...; fig s2a	Kaneda M, Messer K, Ralainirina N, Li H, Leem C, Gorjestani S, et al. PI3Kγ is a molecular switch that controls immune suppression. Nature. 2016;539:437-442 pubmed publisher
flow cytometry; mouse; loading ...; fig 1i	Bernard Valnet R, Yshii L, Quériault C, Nguyen X, Arthaud S, Rodrigues M, et al. CD8 T cell-mediated killing of orexinergic neurons induces a narcolepsy-like phenotype in mice. Proc Natl Acad Sci U S A. 2016;113:10956-61 pubmed publisher
flow cytometry; mouse; loading ...; fig 4e	Hoegl S, Ehrentraut H, Brodsky K, Victorino F, Golden Mason L, Eltzschig H, et al. NK cells regulate CXCR2+ neutrophil recruitment during acute lung injury. J Leukoc Biol. 2017;101:471-480 pubmed publisher
flow cytometry; mouse; loading ...; fig 1d	Nam S, Kang K, Cha J, Kim J, Lee H, Kim Y, et al. Interferon regulatory factor 4 (IRF4) controls myeloid-derived suppressor cell (MDSC) differentiation and function. J Leukoc Biol. 2016;100:1273-1284 pubmed
flow cytometry; mouse; loading ...; fig 1d	Uckelmann H, Blaszkiewicz S, Nicolae C, Haas S, Schnell A, Wurzer S, et al. Extracellular matrix protein Matrilin-4 regulates stress-induced HSC proliferation via CXCR4. J Exp Med. 2016;213:1961-71 pubmed publisher
flow cytometry; mouse; loading ...; fig 8a	Guo H, Cranert S, Lu Y, Zhong M, Zhang S, Chen J, et al. Deletion of Slam locus in mice reveals inhibitory role of SLAM family in NK cell responses regulated by cytokines and LFA-1. J Exp Med. 2016;213:2187-207 pubmed publisher
flow cytometry; mouse; loading ...; fig 1a	Vogel K, Bell L, Galloway A, Ahlfors H, Turner M. The RNA-Binding Proteins Zfp36l1 and Zfp36l2 Enforce the Thymic ?-Selection Checkpoint by Limiting DNA Damage Response Signaling and Cell Cycle Progression. J Immunol. 2016;197:2673-2685 pubmed publisher
flow cytometry; mouse	Yoon J, Leyva Castillo J, Wang G, Galand C, Oyoshi M, Kumar L, et al. IL-23 induced in keratinocytes by endogenous TLR4 ligands polarizes dendritic cells to drive IL-22 responses to skin immunization. J Exp Med. 2016;213:2147-66 pubmed publisher
flow cytometry; mouse; loading ...; fig 1b	Cordova Z, GrÃ¶nholm A, KytÃ¶lÃ¤ V, Taverniti V, HÃ¤mÃ¤lÃ¤inen S, AittomÃ¤ki S, et al. Myeloid cell expressed proprotein convertase FURIN attenuates inflammation. Oncotarget. 2016;7:54392-54404 pubmed publisher
flow cytometry; mouse; loading ...; fig 3d	Lund A, Wagner M, Fankhauser M, Steinskog E, Broggi M, Spranger S, et al. Lymphatic vessels regulate immune microenvironments in human and murine melanoma. J Clin Invest. 2016;126:3389-402 pubmed publisher
flow cytometry; mouse; loading ...; fig 3a	Imhof B, Jemelin S, Ballet R, Vesin C, Schapira M, Karaca M, et al. CCN1/CYR61-mediated meticulous patrolling by Ly6Clow monocytes fuels vascular inflammation. Proc Natl Acad Sci U S A. 2016;113:E4847-56 pubmed publisher
flow cytometry; mouse; loading ...; fig 2a	Boucard Jourdin M, Kugler D, Endale Ahanda M, This S, De Calisto J, Zhang A, et al. ?8 Integrin Expression and Activation of TGF-? by Intestinal Dendritic Cells Are Determined by Both Tissue Microenvironment and Cell Lineage. J Immunol. 2016;197:1968-78 pubmed publisher
flow cytometry; mouse; loading ...; fig 1A	Veinotte L, Gebremeskel S, Johnston B. CXCL16-positive dendritic cells enhance invariant natural killer T cell-dependent IFN? production and tumor control. Oncoimmunology. 2016;5:e1160979 pubmed publisher
flow cytometry; mouse; loading ...; fig 1a	Chen S, Miyazaki M, Chandra V, Fisch K, Chang A, Murre C. Id3 Orchestrates Germinal Center B Cell Development. Mol Cell Biol. 2016;36:2543-52 pubmed publisher
flow cytometry; mouse; fig s6a	Lesina M, Wörmann S, Morton J, Diakopoulos K, Korneeva O, Wimmer M, et al. RelA regulates CXCL1/CXCR2-dependent oncogene-induced senescence in murine Kras-driven pancreatic carcinogenesis. J Clin Invest. 2016;126:2919-32 pubmed publisher
flow cytometry; mouse; fig s1	Fransén Pettersson N, Duarte N, Nilsson J, Lundholm M, Mayans S, Larefalk A, et al. A New Mouse Model That Spontaneously Develops Chronic Liver Inflammation and Fibrosis. PLoS ONE. 2016;11:e0159850 pubmed publisher
flow cytometry; mouse; loading ...; fig 2a	Woytschak J, Keller N, Krieg C, Impellizzieri D, Thompson R, Wynn T, et al. Type 2 Interleukin-4 Receptor Signaling in Neutrophils Antagonizes Their Expansion and Migration during Infection and Inflammation. Immunity. 2016;45:172-84 pubmed publisher
flow cytometry; mouse; loading ...; fig ex1b	Hoppe P, Schwarzfischer M, Loeffler D, Kokkaliaris K, Hilsenbeck O, Moritz N, et al. Early myeloid lineage choice is not initiated by random PU.1 to GATA1 protein ratios. Nature. 2016;535:299-302 pubmed publisher
flow cytometry; mouse; 1:400; loading ...; fig 1h	Ruhland M, Loza A, Capietto A, Luo X, Knolhoff B, Flanagan K, et al. Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis. Nat Commun. 2016;7:11762 pubmed publisher
flow cytometry; mouse; loading ...	Seehus C, Kaye J. In vitro Differentiation of Murine Innate Lymphoid Cells from Common Lymphoid Progenitor Cells. Bio Protoc. 2016;6: pubmed
immunohistochemistry - frozen section; mouse; loading ...; fig 6b	Jordan Williams K, Ramanujam N, Farr A, Ruddell A. The Lymphatic Endothelial mCLCA1 Antibody Induces Proliferation and Growth of Lymph Node Lymphatic Sinuses. PLoS ONE. 2016;11:e0156079 pubmed publisher
flow cytometry; mouse; fig 1a	Kim C, Nakamura M, Hsieh C. Brain trauma elicits non-canonical macrophage activation states. J Neuroinflammation. 2016;13:117 pubmed publisher
flow cytometry; mouse; loading ...; fig 4b	Yang X, Lin Y, Shi Y, Li B, Liu W, Yin W, et al. FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3-CCL2 Signaling. Cancer Res. 2016;76:4124-35 pubmed publisher
flow cytometry; human; 1:200; loading ...; fig 7f flow cytometry; mouse; 1:200; loading ...; fig 5c	Göbel K, Pankratz S, Asaridou C, Herrmann A, Bittner S, Merker M, et al. Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells. Nat Commun. 2016;7:11626 pubmed publisher
flow cytometry; mouse; 1:50; loading ...; fig s1a	Rothhammer V, Mascanfroni I, Bunse L, Takenaka M, Kenison J, Mayo L, et al. Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor. Nat Med. 2016;22:586-97 pubmed publisher
flow cytometry; mouse; 1:400; loading ...; fig s2b	Jain N, Khullar B, Oswal N, Banoth B, Joshi P, Ravindran B, et al. TLR-mediated albuminuria needs TNF?-mediated cooperativity between TLRs present in hematopoietic tissues and CD80 present on non-hematopoietic tissues in mice. Dis Model Mech. 2016;9:707-17 pubmed publisher
flow cytometry; mouse; loading ...; fig 2i	Hull T, Boddu R, Guo L, Tisher C, Traylor A, Patel B, et al. Heme oxygenase-1 regulates mitochondrial quality control in the heart. JCI Insight. 2016;1:e85817 pubmed
flow cytometry; mouse; loading ...; fig s4	Spiegel A, Brooks M, Houshyar S, Reinhardt F, Ardolino M, Fessler E, et al. Neutrophils Suppress Intraluminal NK Cell-Mediated Tumor Cell Clearance and Enhance Extravasation of Disseminated Carcinoma Cells. Cancer Discov. 2016;6:630-49 pubmed publisher
flow cytometry; mouse; loading ...; fig 3d	Jackson S, Jacobs H, Arkatkar T, Dam E, Scharping N, Kolhatkar N, et al. B cell IFN-Î³ receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6. J Exp Med. 2016;213:733-50 pubmed publisher
flow cytometry; mouse; loading ...; fig 3	Frodermann V, Van Duijn J, van Puijvelde G, van Santbrink P, Lagraauw H, de Vries M, et al. Heat-killed Staphylococcus aureus reduces atherosclerosis by inducing anti-inflammatory macrophages. J Intern Med. 2016;279:592-605 pubmed publisher
flow cytometry; mouse; 1:200; fig s7a	Bulla R, Tripodo C, Rami D, Ling G, Agostinis C, Guarnotta C, et al. C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation. Nat Commun. 2016;7:10346 pubmed publisher
flow cytometry; mouse; fig 1e	Tubo N, Fife B, Pagán A, Kotov D, Goldberg M, Jenkins M. Most microbe-specific naïve CD4? T cells produce memory cells during infection. Science. 2016;351:511-4 pubmed publisher
flow cytometry; mouse; fig 7a	Mangum L, CROW J, Stokes J, HOWELL G, Ross M, Pruett S, et al. Exposure to p,p'-DDE Alters Macrophage Reactivity and Increases Macrophage Numbers in Adipose Stromal Vascular Fraction. Toxicol Sci. 2016;150:169-77 pubmed publisher
flow cytometry; mouse; loading ...; fig s3h	Arai S, Kitada K, Yamazaki T, Takai R, Zhang X, Tsugawa Y, et al. Apoptosis inhibitor of macrophage protein enhances intraluminal debris clearance and ameliorates acute kidney injury in mice. Nat Med. 2016;22:183-93 pubmed publisher
flow cytometry; mouse; loading ...	McCubbrey A, Nelson J, Stolberg V, Blakely P, McCloskey L, Janssen W, et al. MicroRNA-34a Negatively Regulates Efferocytosis by Tissue Macrophages in Part via SIRT1. J Immunol. 2016;196:1366-75 pubmed publisher
flow cytometry; mouse; loading ...; fig 2a	Andzinski L, Kasnitz N, Stahnke S, Wu C, Gereke M, von KÃ¶ckritz Blickwede M, et al. Type I IFNs induce anti-tumor polarization of tumor associated neutrophils in mice and human. Int J Cancer. 2016;138:1982-93 pubmed publisher
flow cytometry; mouse; loading ...; fig 1f	Cole C, Verdoni A, Ketkar S, Leight E, Russler Germain D, Lamprecht T, et al. PML-RARA requires DNA methyltransferase 3A to initiate acute promyelocytic leukemia. J Clin Invest. 2016;126:85-98 pubmed publisher
flow cytometry; mouse	Skeldon A, Morizot A, Douglas T, Santoro N, Kursawe R, Kozlitina J, et al. Caspase-12, but Not Caspase-11, Inhibits Obesity and Insulin Resistance. J Immunol. 2016;196:437-47 pubmed publisher
flow cytometry; mouse; fig 3	Zhang Z, Wu N, Lu Y, Davidson D, Colonna M, Veillette A. DNAM-1 controls NK cell activation via an ITT-like motif. J Exp Med. 2015;212:2165-82 pubmed publisher
flow cytometry; mouse; loading ...; fig 2e	Lowe K, Navarro NÃºÃ±ez L, BÃ©nÃ©zech C, Nayar S, Kingston B, Nieswandt B, et al. The expression of mouse CLEC-2 on leucocyte subsets varies according to their anatomical location and inflammatory state. Eur J Immunol. 2015;45:2484-93 pubmed publisher
flow cytometry; mouse; loading ...; fig 2a	Herz J, Johnson K, McGavern D. Therapeutic antiviral T cells noncytopathically clear persistently infected microglia after conversion into antigen-presenting cells. J Exp Med. 2015;212:1153-69 pubmed publisher
flow cytometry; mouse; loading ...; fig s1a	Sei J, Haskett S, Kaminsky L, Lin E, Truckenmiller M, Bellone C, et al. Peptide-MHC-I from Endogenous Antigen Outnumber Those from Exogenous Antigen, Irrespective of APC Phenotype or Activation. PLoS Pathog. 2015;11:e1004941 pubmed publisher
flow cytometry; mouse; tbl s1	Kamachi F, Isshiki T, Harada N, Akiba H, Miyake S. ICOS promotes group 2 innate lymphoid cell activation in lungs. Biochem Biophys Res Commun. 2015;463:739-45 pubmed publisher
flow cytometry; mouse; loading ...; fig s2c	Lal G, Nakayama Y, Sethi A, Singh A, Burrell B, Kulkarni N, et al. Interleukin-10 From Marginal Zone Precursor B-Cell Subset Is Required for Costimulatory Blockade-Induced Transplantation Tolerance. Transplantation. 2015;99:1817-28 pubmed publisher
flow cytometry; mouse; loading ...; fig s3	Jing W, Gershan J, Weber J, Tlomak D, McOlash L, Sabatos Peyton C, et al. Combined immune checkpoint protein blockade and low dose whole body irradiation as immunotherapy for myeloma. J Immunother Cancer. 2015;3:2 pubmed publisher
flow cytometry; mouse; fig 4	Xia H, Ren X, Bolte C, Ustiyan V, Zhang Y, Shah T, et al. Foxm1 regulates resolution of hyperoxic lung injury in newborns. Am J Respir Cell Mol Biol. 2015;52:611-21 pubmed publisher
flow cytometry; mouse; fig 5a	Dai M, Yip Y, Hellstrom I, Hellstrom K. Curing mice with large tumors by locally delivering combinations of immunomodulatory antibodies. Clin Cancer Res. 2015;21:1127-38 pubmed publisher
flow cytometry; mouse; 170 ug/ml	Reeh K, Cardenas K, Bain V, Liu Z, LAURENT M, Manley N, et al. Ectopic TBX1 suppresses thymic epithelial cell differentiation and proliferation during thymus organogenesis. Development. 2014;141:2950-8 pubmed publisher
flow cytometry; mouse	Vogelzang A, Perdomo C, Zedler U, Kuhlmann S, Hurwitz R, Gengenbacher M, et al. Central memory CD4+ T cells are responsible for the recombinant Bacillus Calmette-Guérin ?ureC::hly vaccine's superior protection against tuberculosis. J Infect Dis. 2014;210:1928-37 pubmed publisher
flow cytometry; mouse	Gerber S, Sedlacek A, Cron K, Murphy S, Frelinger J, Lord E. IFN-γ mediates the antitumor effects of radiation therapy in a murine colon tumor. Am J Pathol. 2013;182:2345-54 pubmed publisher
flow cytometry; mouse; fig 1	Chabtini L, Mfarrej B, Mounayar M, Zhu B, Batal I, Dakle P, et al. TIM-3 regulates innate immune cells to induce fetomaternal tolerance. J Immunol. 2013;190:88-96 pubmed publisher
flow cytometry; mouse; 1:500; fig S4	Rose S, Misharin A, Perlman H. A novel Ly6C/Ly6G-based strategy to analyze the mouse splenic myeloid compartment. Cytometry A. 2012;81:343-50 pubmed publisher
flow cytometry; mouse; fig 8	Shen J, Ren H, Tomiyama Miyaji C, Watanabe M, Kainuma E, Inoue M, et al. Resistance and augmentation of innate immunity in mice exposed to starvation. Cell Immunol. 2009;259:66-73 pubmed publisher
flow cytometry; mouse; fig 2	Cuburu N, Kweon M, Song J, Hervouet C, Luci C, Sun J, et al. Sublingual immunization induces broad-based systemic and mucosal immune responses in mice. Vaccine. 2007;25:8598-610 pubmed
flow cytometry; mouse	Reese T, Liang H, Tager A, Luster A, Van Rooijen N, Voehringer D, et al. Chitin induces accumulation in tissue of innate immune cells associated with allergy. Nature. 2007;447:92-6 pubmed
immunohistochemistry - frozen section; mouse; fig 5	Correa de Santana E, Paez Pereda M, Theodoropoulou M, Kenji Nihei O, Gruebler Y, Bozza M, et al. Hypothalamus-pituitary-adrenal axis during Trypanosoma cruzi acute infection in mice. J Neuroimmunol. 2006;173:12-22 pubmed
flow cytometry; mouse; fig 4	Luci C, Hervouet C, Rousseau D, Holmgren J, Czerkinsky C, Anjuere F. Dendritic cell-mediated induction of mucosal cytotoxic responses following intravaginal immunization with the nontoxic B subunit of cholera toxin. J Immunol. 2006;176:2749-57 pubmed
immunohistochemistry - frozen section; mouse; 1:5; fig 1	Schneider B, Fine J, Tiidus P. Indices of leukocyte infiltration and muscle recovery after eccentric contraction-induced injury in young and adult male mice. Orthop Nurs. 2005;24:399-405 pubmed
flow cytometry; mouse	Lu M, Tayu R, Ikawa T, Masuda K, Matsumoto I, Mugishima H, et al. The earliest thymic progenitors in adults are restricted to T, NK, and dendritic cell lineage and have a potential to form more diverse TCRbeta chains than fetal progenitors. J Immunol. 2005;175:5848-56 pubmed
flow cytometry; mouse	Mangan N, Fallon R, Smith P, Van Rooijen N, McKenzie A, Fallon P. Helminth infection protects mice from anaphylaxis via IL-10-producing B cells. J Immunol. 2004;173:6346-56 pubmed
flow cytometry; mouse	Turley S, Poirot L, Hattori M, Benoist C, Mathis D. Physiological beta cell death triggers priming of self-reactive T cells by dendritic cells in a type-1 diabetes model. J Exp Med. 2003;198:1527-37 pubmed
ELISA; mouse; fig 4	Sato A, Hashiguchi M, Toda E, Iwasaki A, Hachimura S, Kaminogawa S. CD11b+ Peyer's patch dendritic cells secrete IL-6 and induce IgA secretion from naive B cells. J Immunol. 2003;171:3684-90 pubmed
flow cytometry; mouse; fig 1	Germeraad W, Kawamoto H, Itoi M, Jiang Y, Amagai T, Katsura Y, et al. Development of thymic microenvironments in vitro is oxygen-dependent and requires permanent presence of T-cell progenitors. J Histochem Cytochem. 2003;51:1225-35 pubmed
flow cytometry; mouse; tbl 1	Kawamoto H, Ohmura K, Fujimoto S, Lu M, Ikawa T, Katsura Y. Extensive proliferation of T cell lineage-restricted progenitors in the thymus: an essential process for clonal expression of diverse T cell receptor beta chains. Eur J Immunol. 2003;33:606-15 pubmed
flow cytometry; mouse; fig 8	Miyakawa R, Miyaji C, Watanabe H, Yokoyama H, Tsukada C, Asakura H, et al. Unconventional NK1.1(-) intermediate TCR cells as major T lymphocytes expanding in chronic graft-versus-host disease. Eur J Immunol. 2002;32:2521-31 pubmed
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flow cytometry; mouse; fig 2	Prasad S, Goodnow C. Cell-intrinsic effects of non-MHC NOD genes on dendritic cell generation in vivo. Int Immunol. 2002;14:677-84 pubmed
flow cytometry; mouse	Xu H, Wipasa J, Yan H, Zeng M, Makobongo M, Finkelman F, et al. The mechanism and significance of deletion of parasite-specific CD4(+) T cells in malaria infection. J Exp Med. 2002;195:881-92 pubmed
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immunohistochemistry - frozen section; human	Coraci I, Husemann J, Berman J, Hulette C, Dufour J, Campanella G, et al. CD36, a class B scavenger receptor, is expressed on microglia in Alzheimer's disease brains and can mediate production of reactive oxygen species in response to beta-amyloid fibrils. Am J Pathol. 2002;160:101-12 pubmed
immunohistochemistry - frozen section; mouse	Burne M, Daniels F, El Ghandour A, Mauiyyedi S, Colvin R, O Donnell M, et al. Identification of the CD4(+) T cell as a major pathogenic factor in ischemic acute renal failure. J Clin Invest. 2001;108:1283-90 pubmed
flow cytometry; mouse	SandrÃ© C, Gleizes A, Forestier F, Gorges Kergot R, Chilmonczyk S, LÃ©onil J, et al. A peptide derived from bovine beta-casein modulates functional properties of bone marrow-derived macrophages from germfree and human flora-associated mice. J Nutr. 2001;131:2936-42 pubmed
flow cytometry; mouse; fig 1	Ohmura K, Kawamoto H, Lu M, Ikawa T, Ozaki S, Nakao K, et al. Immature multipotent hemopoietic progenitors lacking long-term bone marrow-reconstituting activity in the aorta-gonad-mesonephros region of murine day 10 fetuses. J Immunol. 2001;166:3290-6 pubmed
flow cytometry; mouse; fig 1	Shimizu C, Kawamoto H, Yamashita M, Kimura M, Kondou E, Kaneko Y, et al. Progression of T cell lineage restriction in the earliest subpopulation of murine adult thymus visualized by the expression of lck proximal promoter activity. Int Immunol. 2001;13:105-17 pubmed
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flow cytometry; mouse	Shibuya K, Robinson D, Zonin F, Hartley S, Macatonia S, Somoza C, et al. IL-1 alpha and TNF-alpha are required for IL-12-induced development of Th1 cells producing high levels of IFN-gamma in BALB/c but not C57BL/6 mice. J Immunol. 1998;160:1708-16 pubmed
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flow cytometry; mouse	Hattori N, Kawamoto H, Katsura Y. Isolation of the most immature population of murine fetal thymocytes that includes progenitors capable of generating T, B, and myeloid cells. J Exp Med. 1996;184:1901-8 pubmed
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flow cytometry; mouse	Longmore G, Pharr P, Lodish H. A constitutively activated erythropoietin receptor stimulates proliferation and contributes to transformation of multipotent, committed nonerythroid and erythroid progenitor cells. Mol Cell Biol. 1994;14:2266-77 pubmed
flow cytometry; mouse	Li W, Yu J, Michieli P, Beeler J, Ellmore N, Heidaran M, et al. Stimulation of the platelet-derived growth factor beta receptor signaling pathway activates protein kinase C-delta. Mol Cell Biol. 1994;14:6727-35 pubmed
flow cytometry; mouse; fig 1	Macatonia S, Hosken N, Litton M, Vieira P, Hsieh C, Culpepper J, et al. Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells. J Immunol. 1995;154:5071-9 pubmed
flow cytometry; mouse; fig 5	Godfrey D, Kennedy J, Mombaerts P, Tonegawa S, Zlotnik A. Onset of TCR-beta gene rearrangement and role of TCR-beta expression during CD3-CD4-CD8- thymocyte differentiation. J Immunol. 1994;152:4783-92 pubmed
immunoprecipitation; mouse; fig 1	Sanchez Madrid F, Simon P, Thompson S, Springer T. Mapping of antigenic and functional epitopes on the alpha- and beta-subunits of two related mouse glycoproteins involved in cell interactions, LFA-1 and Mac-1. J Exp Med. 1983;158:586-602 pubmed
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product information

Product Type :

Antibody

Product Name :

CD11b Monoclonal Antibody (M1/70)

Catalog # :

MA1-10080

Quantity :

100 ug

Price :

US 207.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Rat

Reactivity :

Human, Mouse, Non-human primate, Rabbit

Applications :

Flow Cytometry: 1 ug/mL, Functional Assay: Assay-dependent, Immunohistochemistry (Frozen): Assay-dependent, Immunoprecipitation: Assay-dependent

Species :

Human, Mouse, Non-human primate, Rabbit

Clone :

M1/70

Isotype :

IgG2b

Storage :

4 C, do not freeze

Description :

CD11b (integrin alpha-M, ITGAM, integrin alpha-X, ITGAX) is a 165 kDa adhesion molecule that associates non-covalently with integrin beta-2 (CD18). The CD11b/CD18 heterodimeric complex is also known as integrin alpha-M beta-2, Mac-1, and CR3 (complement receptor 3). CD11b is expressed on the surface of monocytes/macrophages, granulocytes, activated lymphocytes, a subset of NK cells, a subset of dendritic cells, and microglia in the brain. CD11b/CD18 functions as the receptor for ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), CD14, CD50, CD23, heparin, iC3b, fibrinogen, and Factor X -these adhesions are critical for cell-cell and cell-matrix interactions. CD11b is expressed on 8% of spleen cells, 44% of bone marrow cells, and less than 1% of thymocytes, and is commonly used as a microglial marker in nervous tissue. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Further, peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages. Diseases associated with CD11b dysfunction include systemic lupus erythematosus 6 and ITGAM-related susceptibility to systemic lupus erythematosus.

Immunogen :

B10 mouse spleen cells enriched for T cells

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1 ug/mL, Functional Assay: Assay-dependent, Immunohistochemistry (Frozen): Assay-dependent, Immunoprecipitation: Assay-dependent

Aliases :

antigen CD11b (p170); antigen CD11b (p170); macrophage antigen alpha polypeptide; CD11 antigen-like family member B; CD11b; CD11B (p170); CD11b/CD18; cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; complement component receptor 3 alpha-a; complement receptor type 3; CR3; CR-3 alpha chain; CR3A; F730045J24Rik; integrin alpha M; integrin alpha-M; integrin subunit alpha M; integrin, alpha M; integrin, alpha M (complement component 3 receptor 3 subunit); ITGAM; Leukocyte adhesion receptor MO1; leukocyte integrin alpha-M chain; LOC100351865; Ly-40; MAC1; Mac-1; Mac-1 alpha; Mac-1 alpha (Mac1A); MAC-1 alpha subunit; MAC1A; Mac-1a; macrophage antigen alpha; macrophage antigen alpha polypeptide; MGC117044; MO1A; Neutrophil adherence receptor; neutrophil adherence receptor alpha-M subunit; SLEB6; unnamed protein product

more info or order :

Invitrogen product webpage