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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Hepatitis B Virus X Monoclonal Antibody (X36C)
catalog :
MA1-081
quantity :
100 µg
price :
US 399.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
X36C
reactivity :
Hepatitis B virus
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation
more info or order :
Invitrogen product webpage
citations: 11
Published Application/Species/Sample/DilutionReference
  • chromatin immunoprecipitation; Hepatitis B virus; fig 4
  • western blot; Hepatitis B virus; fig 2
Ghosh A, Ghosh S, Dasgupta D, Ghosh A, Datta S, Sikdar N, et al. Hepatitis B Virus X Protein Upregulates hELG1/ ATAD5 Expression through E2F1 in Hepatocellular Carcinoma. Int J Biol Sci. 2016;12:30-41 pubmed publisher
  • western blot; Hepatitis B virus
Pollicino T, Bellinghieri L, Restuccia A, Raffa G, Musolino C, Alibrandi A, et al. Hepatitis B virus (HBV) induces the expression of interleukin-8 that in turn reduces HBV sensitivity to interferon-alpha. Virology. 2013;444:317-28 pubmed publisher
  • immunocytochemistry; Hepatitis B virus; 1:100
Severi T, Vander Borght S, Libbrecht L, VanAelst L, Nevens F, Roskams T, et al. HBx or HCV core gene expression in HepG2 human liver cells results in a survival benefit against oxidative stress with possible implications for HCC development. Chem Biol Interact. 2007;168:128-34 pubmed
  • western blot; Hepatitis B virus; 1:1000
Cougot D, Wu Y, Cairo S, Caramel J, Renard C, Levy L, et al. The hepatitis B virus X protein functionally interacts with CREB-binding protein/p300 in the regulation of CREB-mediated transcription. J Biol Chem. 2007;282:4277-87 pubmed
  • western blot; Hepatitis B virus; 1:500
Nakajima E, David L, Bystrom C, Shearer T, Azuma M. Calpain-specific proteolysis in primate retina: Contribution of calpains in cell death. Invest Ophthalmol Vis Sci. 2006;47:5469-75 pubmed
  • western blot; Hepatitis B virus
Kanda T, Yokosuka O, Nagao K, Saisho H. State of hepatitis C viral replication enhances activation of NF-kB- and AP-1-signaling induced by hepatitis B virus X. Cancer Lett. 2006;234:143-8 pubmed
Guerrieri F, Belloni L, D Andrea D, Pediconi N, Le Pera L, Testoni B, et al. Genome-wide identification of direct HBx genomic targets. BMC Genomics. 2017;18:184 pubmed publisher
Idrissi M, Hachem H, Koering C, Merle P, Thénoz M, Mortreux F, et al. HBx triggers either cellular senescence or cell proliferation depending on cellular phenotype. J Viral Hepat. 2016;23:130-8 pubmed publisher
Cougot D, Allemand E, Rivière L, Benhenda S, Duroure K, Levillayer F, et al. Inhibition of PP1 phosphatase activity by HBx: a mechanism for the activation of hepatitis B virus transcription. Sci Signal. 2012;5:ra1 pubmed publisher
Karavattathayyil S, Kalkeri G, Liu H, Gaglio P, Garry R, Krause J, et al. Detection of hepatitis C virus RNA sequences in B-cell non-Hodgkin lymphoma. Am J Clin Pathol. 2000;113:391-8 pubmed
Melegari M, Scaglioni P, Wands J. Cloning and characterization of a novel hepatitis B virus x binding protein that inhibits viral replication. J Virol. 1998;72:1737-43 pubmed
product information
Product Type :
Antibody
Product Name :
Hepatitis B Virus X Monoclonal Antibody (X36C)
Catalog # :
MA1-081
Quantity :
100 µg
Price :
US 399.00
Clonality :
Monoclonal
Purity :
HPLC
Host :
Mouse
Reactivity :
Virus
Applications :
ELISA: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1 µg/mL
Species :
Virus
Clone :
X36C
Isotype :
IgG1
Storage :
-20° C, Avoid Freeze/Thaw Cycles
Description :
The hepatitis B virus is an important cause of acute and chronic liver disease. It is also the most common form of parenterally transmitted viral hepatitis. The Hepatitis B X antigen is a 154 amino acid ~17 kDa multifunctional protein involved in the development of liver chirrosis and hepatocellular carcinoma. The virus is estimated to affect some 350 million people worldwide. Immunization against hepatitis B is an important component of preventative medicine and is offered to all children in approximately 30 countries. Hepatitis B virus (HBV) belongs to the Hepadnaviridae family and infection with HBV is usually more serious than infection with hepatitis A virus. In some individuals the infection is not cleared and followed by persistent intracellular viral carriage that can lead to the development of hepatocelular carcinomas. There are currently 400 million HBV carriers worldwide making HBV one of the most common human pathogens.
Immunogen :
Baculovirus expressed recombinant HBx.
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1 µg/mL
Aliases :
HBV; HBVgp3; HepB; HepB X
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA