product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
LAP1 Monoclonal Antibody (RL13)
catalog :
MA1-074
quantity :
200 µL
price :
US 375.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
RL13
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 5
Published Application/Species/Sample/DilutionReference
  • western blot; mouse
Haque F, Lloyd D, Smallwood D, Dent C, Shanahan C, Fry A, et al. SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton. Mol Cell Biol. 2006;26:3738-51 pubmed
Yang L, Guan T, Gerace L. Lamin-binding fragment of LAP2 inhibits increase in nuclear volume during the cell cycle and progression into S phase. J Cell Biol. 1997;139:1077-87 pubmed
Foisner R, Gerace L. Integral membrane proteins of the nuclear envelope interact with lamins and chromosomes, and binding is modulated by mitotic phosphorylation. Cell. 1993;73:1267-79 pubmed
Martin L, Crimaudo C, Gerace L. cDNA cloning and characterization of lamina-associated polypeptide 1C (LAP1C), an integral protein of the inner nuclear membrane. J Biol Chem. 1995;270:8822-8 pubmed
Senior A, Gerace L. Integral membrane proteins specific to the inner nuclear membrane and associated with the nuclear lamina. J Cell Biol. 1988;107:2029-36 pubmed
image
image 1 :
Invitrogen MA1-074 image 1
Immunofluorescent analysis of LAP1 using anti-LAP1 monoclonal antibody (Product# MA1-074) shows staining in NS-1 Cells.
product information
Product Type :
Antibody
Product Name :
LAP1 Monoclonal Antibody (RL13)
Catalog # :
MA1-074
Quantity :
200 µL
Price :
US 375.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Human, Mouse, Rat
Applications :
Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:20-1:50, Immunoprecipitation: Assay-dependent, Western Blot: 1:200
Species :
Human, Mouse, Rat
Clone :
RL13
Isotype :
IgG1
Storage :
-20° C, Avoid Freeze/Thaw Cycles
Description :
Exopeptidase which selectively removes arginine and/or lysine residues from the N-terminus of several peptide substrates including Arg(0)-Leu-enkephalin, Arg(0)-Met-enkephalin and Arg(-1)-Lys(0)-somatostatin-14. Can hydrolyze leukotriene A4 (LTA-4) into leukotriene B4 (LTB-4).
Immunogen :
Pore complex-lamina fraction isolated from rat liver nuclear envelopes.
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:20-1:50, Immunoprecipitation: Assay-dependent, Western Blot: 1:200
Aliases :
lamina-associated polypeptide 1B; Lamina-associated polypeptide 1C; Lamin-associated protein 1B; LAP1; LAP1B; Lap1c; Tor1aip1; torsin 1A interacting protein 1; torsin A interacting protein 1; torsin-1A-interacting protein 1
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA