| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot knockout validation; mouse; 1:1000; loading ...; fig 3b
| Ida S, Morino K, Sekine O, Ohashi N, Kume S, Chano T, et al. Diverse metabolic effects of O-GlcNAcylation in the pancreas but limited effects in insulin-sensitive organs in mice. Diabetologia. 2017;60:1761-1769 pubmed publisher |
- western blot; human; loading ...; fig 2a
| Han J, Valdez J, Ho D, Lee C, Kim H, Wang X, et al. Nuclear factor-erythroid-2 related transcription factor-1 (Nrf1) is regulated by O-GlcNAc transferase. Free Radic Biol Med. 2017;110:196-205 pubmed publisher |
- western blot; human; loading ...; fig 3b
| Okuda T. PUGNAc treatment provokes globotetraosylceramide accumulation in human umbilical vein endothelial cells. Biochem Biophys Res Commun. 2017;487:76-82 pubmed publisher |
- western blot; human; 1:200; fig 2
| Qiao Z, Dang C, Zhou B, Li S, Zhang W, Jiang J, et al. Downregulation of O-linked N-acetylglucosamine transferase by RNA interference decreases MMP9 expression in human esophageal cancer cells. Oncol Lett. 2016;11:3317-3323 pubmed |
- western blot; rat; loading ...; fig 3o
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| Wang J, Wang Z, Yuan J, Wang J, Shen X. The positive feedback between ACSL4 expression and O-GlcNAcylation contributes to the growth and survival of hepatocellular carcinoma. Aging (Albany NY). 2020;12:7786-7800 pubmed publisher |
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| Kakade P, Budnar S, Kalraiya R, Vaidya M. Functional Implications of O-GlcNAcylation-dependent Phosphorylation at a Proximal Site on Keratin 18. J Biol Chem. 2016;291:12003-13 pubmed publisher |
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| Borghgraef P, Menuet C, Theunis C, Louis J, Devijver H, Maurin H, et al. Increasing brain protein O-GlcNAc-ylation mitigates breathing defects and mortality of Tau.P301L mice. PLoS ONE. 2013;8:e84442 pubmed publisher |
| Graham D, Gray A, Joyce J, Yu D, O Moore J, Carlson G, et al. Increased O-GlcNAcylation reduces pathological tau without affecting its normal phosphorylation in a mouse model of tauopathy. Neuropharmacology. 2014;79:307-13 pubmed publisher |
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| Cameron A, Giacomozzi B, Joyce J, Gray A, Graham D, Ousson S, et al. Generation and characterization of a rabbit monoclonal antibody site-specific for tau O-GlcNAcylated at serine 400. FEBS Lett. 2013;587:3722-8 pubmed publisher |
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| Ogawa M, Sakakibara Y, Kamemura K. Requirement of decreased O-GlcNAc glycosylation of Mef2D for its recruitment to the myogenin promoter. Biochem Biophys Res Commun. 2013;433:558-62 pubmed publisher |
| Jin N, Qian W, Yin X, Zhang L, Iqbal K, Grundke Iqbal I, et al. CREB regulates the expression of neuronal glucose transporter 3: a possible mechanism related to impaired brain glucose uptake in Alzheimer's disease. Nucleic Acids Res. 2013;41:3240-56 pubmed publisher |
| Kim S, Kang H, Han J, Park S. The transcription factor Sp1 is responsible for aging-dependent altered nucleocytoplasmic trafficking. Aging Cell. 2012;11:1102-9 pubmed publisher |
| Andrés Bergós J, Tardio L, Larrañaga Vera A, Gomez R, Herrero Beaumont G, Largo R. The increase in O-linked N-acetylglucosamine protein modification stimulates chondrogenic differentiation both in vitro and in vivo. J Biol Chem. 2012;287:33615-28 pubmed |
| Gawlowski T, Suarez J, Scott B, Torres Gonzalez M, Wang H, Schwappacher R, et al. Modulation of dynamin-related protein 1 (DRP1) function by increased O-linked-?-N-acetylglucosamine modification (O-GlcNAc) in cardiac myocytes. J Biol Chem. 2012;287:30024-34 pubmed publisher |
| Shi J, Wu S, Dai C, Li Y, Grundke Iqbal I, Iqbal K, et al. Diverse regulation of AKT and GSK-3? by O-GlcNAcylation in various types of cells. FEBS Lett. 2012;586:2443-50 pubmed publisher |
| Duval C, Gaudreault M, Vigneault F, Touzel Deschênes L, Rochette P, Masson Gadais B, et al. Rescue of the transcription factors Sp1 and NFI in human skin keratinocytes through a feeder-layer-dependent suppression of the proteasome activity. J Mol Biol. 2012;418:281-99 pubmed publisher |
| Facundo H, Brainard R, Watson L, Ngoh G, Hamid T, Prabhu S, et al. O-GlcNAc signaling is essential for NFAT-mediated transcriptional reprogramming during cardiomyocyte hypertrophy. Am J Physiol Heart Circ Physiol. 2012;302:H2122-30 pubmed publisher |
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| Ko Y, Tsai W, Wang P, Wu I, Lin S, Chen Y, et al. Suppressive regulation of KSHV RTA with O-GlcNAcylation. J Biomed Sci. 2012;19:12 pubmed publisher |
| Ogawa M, Mizofuchi H, Kobayashi Y, Tsuzuki G, Yamamoto M, Wada S, et al. Terminal differentiation program of skeletal myogenesis is negatively regulated by O-GlcNAc glycosylation. Biochim Biophys Acta. 2012;1820:24-32 pubmed publisher |
| Habegger K, Penque B, Sealls W, Tackett L, Bell L, Blue E, et al. Fat-induced membrane cholesterol accrual provokes cortical filamentous actin destabilisation and glucose transport dysfunction in skeletal muscle. Diabetologia. 2012;55:457-67 pubmed publisher |
| Touw K, Chakraborty S, Zhang W, Obukhov A, Tune J, Gunst S, et al. Altered calcium signaling in colonic smooth muscle of type 1 diabetic mice. Am J Physiol Gastrointest Liver Physiol. 2012;302:G66-76 pubmed publisher |
| Hirose K, Tsutsumi Y, Tsutsumi R, Shono M, Katayama E, Kinoshita M, et al. Role of the O-linked ?-N-acetylglucosamine in the cardioprotection induced by isoflurane. Anesthesiology. 2011;115:955-62 pubmed publisher |
| Beriault D, Sharma S, Shi Y, Khan M, Werstuck G. Glucosamine-supplementation promotes endoplasmic reticulum stress, hepatic steatosis and accelerated atherogenesis in apoE-/- mice. Atherosclerosis. 2011;219:134-40 pubmed publisher |
| Keembiyehetty C, Krzeslak A, Love D, Hanover J. A lipid-droplet-targeted O-GlcNAcase isoform is a key regulator of the proteasome. J Cell Sci. 2011;124:2851-60 pubmed publisher |
| Guinez C, Filhoulaud G, Rayah Benhamed F, Marmier S, Dubuquoy C, Dentin R, et al. O-GlcNAcylation increases ChREBP protein content and transcriptional activity in the liver. Diabetes. 2011;60:1399-413 pubmed publisher |
| Zhu Q, Zhou L, Yang Z, Lai M, Xie H, Wu L, et al. O-GlcNAcylation plays a role in tumor recurrence of hepatocellular carcinoma following liver transplantation. Med Oncol. 2012;29:985-93 pubmed publisher |
| Mondoux M, Love D, Ghosh S, Fukushige T, Bond M, Weerasinghe G, et al. O-linked-N-acetylglucosamine cycling and insulin signaling are required for the glucose stress response in Caenorhabditis elegans. Genetics. 2011;188:369-82 pubmed publisher |
| Bimboese P, Gibson C, Schmidt S, Xiang W, Ehrlich B. Isoform-specific regulation of the inositol 1,4,5-trisphosphate receptor by O-linked glycosylation. J Biol Chem. 2011;286:15688-97 pubmed publisher |
| Park S, Park S, Baek J, Jy Y, Kim K, Roth J, et al. Protein O-GlcNAcylation regulates Drosophila growth through the insulin signaling pathway. Cell Mol Life Sci. 2011;68:3377-84 pubmed publisher |
| Ogawa M, Adachi T, Ikegami S, Kato K, Yamamoto A, Kamemura K. Characterization of O-GlcNAcylation in starfish (Asterina pectinifera) development from fertilization to bipinnaria larva. Biosci Biotechnol Biochem. 2011;75:358-61 pubmed |
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| Kommaddi R, Dickson K, Barker P. Stress-induced expression of the p75 neurotrophin receptor is regulated by O-GlcNAcylation of the Sp1 transcription factor. J Neurochem. 2011;116:396-405 pubmed publisher |
| Lafontaine Lacasse M, Doré G, Picard F. Hexosamines stimulate apoptosis by altering SIRT1 action and levels in rodent pancreatic ?-cells. J Endocrinol. 2011;208:41-9 pubmed publisher |
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| Srikanth B, Vaidya M, Kalraiya R. O-GlcNAcylation determines the solubility, filament organization, and stability of keratins 8 and 18. J Biol Chem. 2010;285:34062-71 pubmed publisher |
| Yokoe S, Asahi M, Takeda T, Otsu K, Taniguchi N, Miyoshi E, et al. Inhibition of phospholamban phosphorylation by O-GlcNAcylation: implications for diabetic cardiomyopathy. Glycobiology. 2010;20:1217-26 pubmed publisher |
| Hardiville S, Hoedt E, Mariller C, Benaïssa M, Pierce A. O-GlcNAcylation/phosphorylation cycling at Ser10 controls both transcriptional activity and stability of delta-lactoferrin. J Biol Chem. 2010;285:19205-18 pubmed publisher |
| Kodiha M, Tran D, Morogan A, Qian C, Stochaj U. Dissecting the signaling events that impact classical nuclear import and target nuclear transport factors. PLoS ONE. 2009;4:e8420 pubmed publisher |
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| D Apolito M, Du X, Zong H, Catucci A, Maiuri L, Trivisano T, et al. Urea-induced ROS generation causes insulin resistance in mice with chronic renal failure. J Clin Invest. 2010;120:203-13 pubmed publisher |
| Anthonisen E, Berven L, Holm S, Nygard M, Nebb H, Grønning Wang L. Nuclear receptor liver X receptor is O-GlcNAc-modified in response to glucose. J Biol Chem. 2010;285:1607-15 pubmed publisher |
| James L, Le C, Scholey J. Influence of glucosamine on glomerular mesangial cell turnover: implications for hyperglycemia and hexosamine pathway flux. Am J Physiol Endocrinol Metab. 2010;298:E210-21 pubmed publisher |
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| Wei Q, Eviatar Ribak T, Miskimins W, Miskimins R. Galectin-4 is involved in p27-mediated activation of the myelin basic protein promoter. J Neurochem. 2007;101:1214-23 pubmed |
| Dehennaut V, Lefebvre T, Sellier C, Leroy Y, Gross B, Walker S, et al. O-linked N-acetylglucosaminyltransferase inhibition prevents G2/M transition in Xenopus laevis oocytes. J Biol Chem. 2007;282:12527-36 pubmed |
| Robinson K, Ball L, Buse M. Reduction of O-GlcNAc protein modification does not prevent insulin resistance in 3T3-L1 adipocytes. Am J Physiol Endocrinol Metab. 2007;292:E884-90 pubmed |
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| Forsythe M, Love D, Lazarus B, Kim E, Prinz W, Ashwell G, et al. Caenorhabditis elegans ortholog of a diabetes susceptibility locus: oga-1 (O-GlcNAcase) knockout impacts O-GlcNAc cycling, metabolism, and dauer. Proc Natl Acad Sci U S A. 2006;103:11952-7 pubmed |
| Martin A, Rojas S, Chamorro A, Falcon C, Bargallo N, Planas A. Why does acute hyperglycemia worsen the outcome of transient focal cerebral ischemia? Role of corticosteroids, inflammation, and protein O-glycosylation. Stroke. 2006;37:1288-95 pubmed |
| Hu P, Berkowitz P, Madden V, Rubenstein D. Stabilization of plakoglobin and enhanced keratinocyte cell-cell adhesion by intracellular O-glycosylation. J Biol Chem. 2006;281:12786-91 pubmed |
| Goldberg H, Whiteside C, Hart G, Fantus I. Posttranslational, reversible O-glycosylation is stimulated by high glucose and mediates plasminogen activator inhibitor-1 gene expression and Sp1 transcriptional activity in glomerular mesangial cells. Endocrinology. 2006;147:222-31 pubmed |
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| Masson Gadais B, Fugère C, Paquet C, Leclerc S, Lefort N, Germain L, et al. The feeder layer-mediated extended lifetime of cultured human skin keratinocytes is associated with altered levels of the transcription factors Sp1 and Sp3. J Cell Physiol. 2006;206:831-42 pubmed |
| Nanashima N, Asano J, Hayakari M, Nakamura T, Nakano H, Yamada T, et al. Nuclear localization of STAT5A modified with O-linked N-acetylglucosamine and early involution in the mammary gland of Hirosaki hairless rat. J Biol Chem. 2005;280:43010-6 pubmed |
| Majumdar G, Wright J, Markowitz P, Martinez Hernandez A, Raghow R, Solomon S. Insulin stimulates and diabetes inhibits O-linked N-acetylglucosamine transferase and O-glycosylation of Sp1. Diabetes. 2004;53:3184-92 pubmed |
| Lefebvre T, Pinte S, Guerardel C, Deltour S, Martin Soudant N, Slomianny M, et al. The tumor suppressor HIC1 (hypermethylated in cancer 1) is O-GlcNAc glycosylated. Eur J Biochem. 2004;271:3843-54 pubmed |
| Liu F, Iqbal K, Grundke Iqbal I, Hart G, Gong C. O-GlcNAcylation regulates phosphorylation of tau: a mechanism involved in Alzheimer's disease. Proc Natl Acad Sci U S A. 2004;101:10804-9 pubmed |
| Dudognon P, Maeder Garavaglia C, Carpentier J, Paccaud J. Regulation of a COPII component by cytosolic O-glycosylation during mitosis. FEBS Lett. 2004;561:44-50 pubmed |
| Andreozzi F, D Alessandris C, Federici M, Laratta E, Del Guerra S, Del Prato S, et al. Activation of the hexosamine pathway leads to phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 and impairs the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin insulin biosynthetic pathway in RIN pancreatic beta-cel. Endocrinology. 2004;145:2845-57 pubmed |
| Cieniewski Bernard C, Bastide B, Lefebvre T, Lemoine J, Mounier Y, Michalski J. Identification of O-linked N-acetylglucosamine proteins in rat skeletal muscle using two-dimensional gel electrophoresis and mass spectrometry. Mol Cell Proteomics. 2004;3:577-85 pubmed |
| Sümegi M, Hunyadi Gulyas E, Medzihradszky K, Udvardy A. 26S proteasome subunits are O-linked N-acetylglucosamine-modified in Drosophila melanogaster. Biochem Biophys Res Commun. 2003;312:1284-9 pubmed |
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