RTN1 Monoclonal Antibody (RNL-4) | Invitrogen MA1-06815 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

RTN1 Monoclonal Antibody (RNL-4)

catalog :

MA1-06815

quantity :

100 µg

price :

US 375.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

RNL-4

reactivity :

human, rat, pigs

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunoprecipitation; human immunocytochemistry; human western blot; human	Chen L, Wan L, Du J, Shen Y. Identification of MANF as a protein interacting with RTN1-C. Acta Biochim Biophys Sin (Shanghai). 2015;47:91-7 pubmed publisher

product information

Product Type :

Antibody

Product Name :

RTN1 Monoclonal Antibody (RNL-4)

Catalog # :

MA1-06815

Quantity :

100 µg

Price :

US 375.00

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Human, Porcine, Rat

Applications :

Flow Cytometry: 1:50 - 1:100, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Frozen): 1:50-1:100, Western Blot: 1:100 - 1:500

Species :

Human, Porcine, Rat

Clone :

RNL-4

Isotype :

IgG1

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

Reticulon-1 was formerly designated NSP for Neuroendocrine-Specific-Protein, because it is specifically expressed in neural and neuroendocrine tissues. The NSP-gene has been mapped by fluorescence in situ hybridization to human chromosome 14q21-q22. The NSP-gene encodes three overlapping proteins, i.e. reticulon-1A (NSP-A), reticulon-1B (NSP-B), and reticulon-1C (NSP-C). These proteins were found to be anchored to membranes of the endoplasmic reticulum through their common carboxy-terminal regions. Reticulon-1A is a protein with a molecular weight of approximately 135 kDa, which occurs in various isoforms presumably depending on the degree of phosphorylation of serine residues. In lung cancer diagnosis Reticulon-1A appeared to be a reliable marker for the detection of neuroendocrine differentiation, since most of the small cell lung carcinoma (SCLC) and carcinoid tumors showed expression of Reticulon-1A. Reticulon-1B is a phosphoprotein with a MW of 45 kDa and is restricted to the lung cancer cell line NCI-H82. Reticulon-1B is so far not found in human tissues. Reticulon-1C is a protein with a MW of 23 kDa which is not phosphorylated and is found with Reticulon-1A in SCLC (cell lines) and not in non-SCLC (cell cultures).

Immunogen :

Synthetic peptide encompassing the unique 20 N-terminal amino acid sequence of reticulon-1C.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:50 - 1:100, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Frozen): 1:50-1:100, Western Blot: 1:100 - 1:500

Aliases :

0710005K15Rik; 4930441F12Rik; I79_024631; LOC100750648; MGC133250; MGC40985; Neuroendocrine-specific protein; Nsp; R75279; reticulon 1; reticulon-1; RP23-450G14.1; RTN1; Rtn1-a; Rtn1-b; Rtn1-c; S-rex

more info or order :

Invitrogen product webpage