PKP3 Monoclonal Antibody (12B11F8) | Invitrogen MA1-06510 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PKP3 Monoclonal Antibody (12B11F8)

catalog :

MA1-06510

quantity :

100µL

price :

330 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

12B11F8

reactivity :

human, mouse, dog, pig

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - frozen section

product information

Product Type :

Antibody

Product Name :

PKP3 Monoclonal Antibody (12B11F8)

Catalog # :

MA1-06510

Quantity :

100µL

Price :

330 USD

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Canine, Human, Mouse, Porcine

Applications :

Immunocytochemistry: 1:25-1:100, Immunohistochemistry (Frozen): 1:25-1:100, Immunoprecipitation: Assay dependent, Western Blot: 1:100-1:1000

Species :

Canine, Human, Mouse, Porcine

Clone :

12B11F8

Isotype :

IgG1

Storage :

4°C or -20°C if preferred

Description :

Plakophilin-3 is an Armadillo-like protein present in nuclei and desmosomes of epithelial cells. The expression pattern of this protein seems to be largely restricted to epithelial cell types. Plakophilin-3 can be detected along cell borders in a punctuate staining pattern typical for desmosomal proteins. In addition to the desmosomal immunolocalisation, immunostaining was observed as bright nuclear speckles. Thus, like plakophilin-1 and-2, plakophilin-3 displays a dual intracellular localisation in the desmosomal plaque and in the cell nucleus, and therefore is probably involved in signal transduction pathways between the plasma membrane and the nucleus. The human protein has a predicted molecular mass of ~87 kD.

Immunogen :

Synthetic peptide corresponding to residues 779-793 of human plakophilin-3 coupled to KLH.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:25-1:100, Immunohistochemistry (Frozen): 1:25-1:100, Immunoprecipitation: Assay dependent, Western Blot: 1:100-1:1000