This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
E-selectin Monoclonal Antibody (UZ5)
catalog :
MA1-06505
quantity :
100 ug
price :
US 484.00
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
UZ5

The same clone is also sold as:
reactivity :
mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
product information
Product Type :
Antibody
Product Name :
E-selectin Monoclonal Antibody (UZ5)
Catalog # :
MA1-06505
Quantity :
100 ug
Price :
US 484.00
Clonality :
Monoclonal
Purity :
purified
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 1:100-1:200, Immunocytochemistry: 1:100-1:200, Immunohistochemistry (Frozen): 1:100-1:200, Immunoprecipitation: 1:100-1:200, Western Blot: 1:100-1:200
Species :
Mouse
Clone :
UZ5
Isotype :
IgG2b
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
Leukocytes adhere to the blood vessel endothelium during extravasation in postcapillary venules of lymph nodes. In addition, leukocyte adhesion occurs in the capillaries and small venules at any site in the body after onset of inflammation. This response is immediate and involves a cascade of adhesion receptors. At the endothelial surface members of the selectin and immunoglobulin superfamilies participate in this cascade. Selectins are C-type cell surface lectins that play a role in leukocyte adhesion to the blood vessel wall endothelium. E-selectin (CD62E) is an endothelial cell specific selectin that is expressed only after activation with proinflammatory cytokines. In vitro experiments have shown that IL-1, TNFalpha and bacterial wall components like lipopolysaccharides induce the transcription of E-selectin in a NFkB dependent signaling cascade. E-selectin has been associated with blood vessel endothelium in diverse inflammatory situations.
Immunogen :
LPS-activated mlEND1 cells expressing E-selectin at their cell surface.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:100-1:200, Immunocytochemistry: 1:100-1:200, Immunohistochemistry (Frozen): 1:100-1:200, Immunoprecipitation: 1:100-1:200, Western Blot: 1:100-1:200
Aliases :
CD62 antigen-like family member E; CD62E; e selectin; Elam; ELAM1; ELAM-1; endothelial adhesion molecule 1; endothelial leukocyte adhesion molecule; endothelial leukocyte adhesion molecule 1; endothelial leukocyte adhesion molecule I; ESEL; E-selectin; LECAM2; leukocyte endothelial cell adhesion molecule 2; leukocyte-endothelial cell adhesion molecule 2; RP1-117P20.2; SELE; selectin E; selectin E (endothelial adhesion molecule 1); selectin, endothelial cell
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA