Desmin Monoclonal Antibody (D9) | Invitrogen MA1-06401 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Desmin Monoclonal Antibody (D9)

catalog :

MA1-06401

quantity :

100 µg

price :

US 425.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

reactivity :

human, mouse, rat, chicken, pigs , domestic rabbit

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; rat; 1:1000; fig s1	Lesmana R, Sinha R, Singh B, Zhou J, Ohba K, Wu Y, et al. Thyroid Hormone Stimulation of Autophagy Is Essential for Mitochondrial Biogenesis and Activity in Skeletal Muscle. Endocrinology. 2016;157:23-38 pubmed publisher
	Siang D, Lim Y, Kyaw A, Win K, Chia S, Degirmenci U, et al. The RNA-binding protein HuR is a negative regulator in adipogenesis. Nat Commun. 2020;11:213 pubmed publisher
	Scott K, Frydman G, Fox J, Bakthavatchalu V. Spontaneous Urinary Bladder Leiomyoma in a Rhesus Macaque (Macaca mulatta). Comp Med. 2018;68:243-247 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Desmin Monoclonal Antibody (D9)

Catalog # :

MA1-06401

Quantity :

100 µg

Price :

US 425.00

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Chicken, Human, Mouse, Porcine, Rabbit, Rat

Applications :

Immunohistochemistry (Frozen): 1:25-1:200, Immunohistochemistry (Paraffin): 1:25-1:200, Western Blot: 1:100-1:1,000

Species :

Chicken, Human, Mouse, Porcine, Rabbit, Rat

Clone :

Isotype :

IgG1

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

Desmin (approximately 53 kDa) exhibits a high degree of tissue specificity, its expression being predominantly confined to all types of muscle cells (cardiac, skeletal and smooth muscle). Regulation of desmin expression is stage and tissue-specific, since it is induced during terminal development of, for example, skeletal muscle cell differentiation. In skeletal en cardiac muscle cells desmin is localized in the Z-disk region and at the intercalated disk. The expression pattern of desmin in smooth muscle is much more heterogenous. Coexpression of vimentin and desmin has been observed in tumors derived from muscle tissue, i.e. rhabdomyosarcomas and leiomyosarcomas. Furthermore, during myocard dysfunction dramatic changes in the distribution of desmin have been observed.

Immunogen :

Desmin isolated from human leiomyoma.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Frozen): 1:25-1:200, Immunohistochemistry (Paraffin): 1:25-1:200, Western Blot: 1:100-1:1,000

Aliases :

CMD1I; CSM1; CSM2; DES; Desmin; desmin-like protein; FLJ12025; FLJ39719; FLJ41013; FLJ41793; I79_018932; intermediate filament protein; LGMD2R; MFM1; muscle-specific intermediate filament desmin; muscle-specific intermediate filament protein; mutant desmin p.K241E; SCPNK; similar to desmin

more info or order :

Invitrogen product webpage