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antibody

Cytokeratin 10 Monoclonal Antibody (RKSE60)

MA1-06319

100 µg

US 399.00

monoclonal

mouse

nonconjugated

RKSE60

human, mouse, rat, dogs, pigs

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section

Cytokeratin 10 Monoclonal Antibody (RKSE60)

MA1-06319

100 µg

US 399.00

Monoclonal

purified

Mouse

Canine, Human, Mouse, Porcine, Rat, Zebrafish

Flow Cytometry: 1:100 - 1:200, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Frozen): 1:100-1:200, Western Blot: 1:100-1:1,000

Canine, Human, Mouse, Porcine, Rat, Zebrafish

RKSE60

IgG1

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (i.e., skin) and non-keratinizing cells (i.e. mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins have also been found in some microvascular endothelial cells. At least 20 different cytokeratins (CK) in the molecular range of 40-70 kDa and isoelectric points of 5-8. 5 can be identified using two dimensional gel electrophoresis. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Monoclonal antibodies to cytokeratin proteins can be useful markers for tumor identification and classification.

Cytokeratins from human epidermal cells.

Liquid

Flow Cytometry: 1:100 - 1:200, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Frozen): 1:100-1:200, Western Blot: 1:100-1:1,000

56 kDa cytokeratin; BCIE; BIE; CK10; CK-10; CK-17; cytokeratin 10; cytokeratin-10; cytokeratin-17; D130054E02Rik; EHK; epidermal keratin 10; epithelial keratin 10; intermediate filament protein; K10; K1C1; Ka10; Ker10; keratin 10; keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris); keratin 10, type I; keratin complex 1, acidic, gene 10; keratin, type I cytoskeletal 10; Keratin, type I cytoskeletal 59 kDa; keratin-10; keratin-17; KPP; Krt-1.10; KRT10; krt10 {ECO:0000250; Krt1-10; suprabasal cytokeratin 10; type I keratin KA10; UniProtKB:P13645}