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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Cytokeratin 4 Monoclonal Antibody (6B10)
catalog :
MA1-06313
quantity :
100 µg
price :
US 375.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
6B10
reactivity :
human, dogs, zebrafish , cat
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry
more info or order :
citations: 3
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; fig 2
Qi H, Zheng X, Yuan X, Pflugfelder S, Li D. Potential localization of putative stem/progenitor cells in human bulbar conjunctival epithelium. J Cell Physiol. 2010;225:180-5 pubmed publisher
  • immunohistochemistry; human; 1:50
Locke M, Hyland P, Irwin C, Mackenzie I. Modulation of gingival epithelial phenotypes by interactions with regionally defined populations of fibroblasts. J Periodontal Res. 2008;43:279-89 pubmed publisher
Toivola D, Zhou Q, English L, Omary M. Type II keratins are phosphorylated on a unique motif during stress and mitosis in tissues and cultured cells. Mol Biol Cell. 2002;13:1857-70 pubmed
product information
Product Type :
Antibody
Product Name :
Cytokeratin 4 Monoclonal Antibody (6B10)
Catalog # :
MA1-06313
Quantity :
100 µg
Price :
US 375.00
Clonality :
Monoclonal
Purity :
purified
Host :
Mouse
Reactivity :
Canine, Feline, Human, Zebrafish
Applications :
Flow Cytometry: 1:25-1:200, Immunocytochemistry: Assay-dependent, Western Blot: 1:100-1:1,000
Species :
Canine, Feline, Human, Zebrafish
Clone :
6B10
Isotype :
IgG1
Storage :
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Description :
Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between approximately40 kDa and approximately68 kDa and isoelectric pH between 4. 9-7. 8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
Immunogen :
Cytokeratin preparation extracted from human esophagus.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:25-1:200, Immunocytochemistry: Assay-dependent, Western Blot: 1:100-1:1,000
Aliases :
57kd keratin; 57kDa keratin; AW108092; cb59; CK4; CK-4; CYK4; cytokeratin; cytokeratin 4; cytokeratin-4; Cytoskeletal 57 kDa keratin; etID20321.6; FLJ31692; intermediate filament protein; K4; Kb4; keratin 4; keratin 4, type II; keratin 8; keratin complex 2, basic, gene 4; keratin, type II cytoskeletal 4; Keratin-4; Krt-2.4; Krt2-4; Krt4; krt4 {ECO:0000250; krt4 protein; krt8; type II basic cytokeratin; type II keratin Kb4; type-II keratin Kb4; UniProtKB:P19013}; WSN1; wu:fa91a11; wu:fd19e09; wu:fl23c09; zf-K8
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA