K-cadherin Monoclonal Antibody (2B6) | Invitrogen MA1-06305 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

K-cadherin Monoclonal Antibody (2B6)

catalog :

MA1-06305

quantity :

100 µL

price :

US 399.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2B6

reactivity :

human, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 3a	Goeppert B, Ernst C, Baer C, Roessler S, Renner M, Mehrabi A, et al. Cadherin-6 is a putative tumor suppressor and target of epigenetically dysregulated miR-429 in cholangiocarcinoma. Epigenetics. 2016;11:780-790 pubmed
	Guagliardo N, Klein P, Gancayco C, Lu A, Leng S, Makarem R, et al. Angiotensin II induces coordinated calcium bursts in aldosterone-producing adrenal rosettes. Nat Commun. 2020;11:1679 pubmed publisher

image

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product information

Product Type :

Antibody

Product Name :

K-cadherin Monoclonal Antibody (2B6)

Catalog # :

MA1-06305

Quantity :

100 µL

Price :

US 399.00

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Human, Rat

Applications :

Immunocytochemistry: 1:25-1:50, Immunohistochemistry (Frozen): 1:25-1:50, Immunohistochemistry (Paraffin): 1:25-1:50, Western Blot: 1:25-1:250

Species :

Human, Rat

Clone :

2B6

Isotype :

IgG1

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

Cadherins constitute a family of transmembrane glycoproteins involved in Ca2+-dependent cell-cell interactions. The members of this family are differentially expressed in various tissues. They function in the maintenance of tissue integrity and morphogenesis. Cadherins are divided into type I and type II subgroups. Type I cadherins include epithelial cadherin (E-cadherin, cadherin-1 or uvomorulin), neural cadherin (N-cadherin or cadherin-2), placental cadherin (P-cadherin or cadherin-3) and retinal cadherin (R-cadherin or cadherin-4), whereas kidney cadherin (K-cadherin or cadherin-6) and osteoblast cadherin (OB-cadherin or cadherin-11) are type II cadherins. Cadherin-6 is expressed in the proximal tubule epithelium of the kidney from which most renal cell carcinomas are derived.

Immunogen :

Affinity purified, extracellular domain of human cadherin-6-GST fusion protein

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:25-1:50, Immunohistochemistry (Frozen): 1:25-1:50, Immunohistochemistry (Paraffin): 1:25-1:50, Western Blot: 1:25-1:250

Aliases :

CAD6; CADH6; cadherin 6; cadherin 6, type 2, K-cadherin; cadherin 6, type 2, K-cadherin (fetal kidney); Cadherin6; cadherin-6; Cdh6; k cadherin; KCAD; K-cadherin; Kidney cadherin

more info or order :

Invitrogen product webpage