Cytohesin 1/2 Monoclonal Antibody (6G11) | Invitrogen MA1-062 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Cytohesin 1/2 Monoclonal Antibody (6G11)

catalog :

MA1-062

quantity :

100 ug

price :

US 399.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6G11

The same clone is also sold as:

Novus Biologicals: NBP2-22513

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

citations: 2

Reference
Cason S, Holzbaur E. Axonal transport of autophagosomes is regulated by dynein activators JIP3/JIP4 and ARF/RAB GTPases. bioRxiv. 2023;: pubmed publisher
Garceau V, Houle M, Chouinard F, Gagnon S, Harbour D, Naccache P, et al. Characterization of cytohesin-1 monoclonal antibodies: expression in neutrophils and during granulocytic maturation of HL-60 cells. J Immunol Methods. 2001;249:121-36 pubmed

product information

Product Type :

Antibody

Product Name :

Cytohesin 1/2 Monoclonal Antibody (6G11)

Catalog # :

MA1-062

Quantity :

100 ug

Price :

US 399.00

Clonality :

Monoclonal

Purity :

PEG precipitation

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:200-1:500, Immunoprecipitation: Assay-dependent, Western Blot: 1.0 ug/mL

Species :

Human, Mouse

Clone :

6G11

Isotype :

IgG1

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This gene is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. The encoded protein is 83% homologous to that of CYTH2.

Immunogen :

Purified, His-tagged cytohesin-1.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:200-1:500, Immunoprecipitation: Assay-dependent, Western Blot: 1.0 ug/mL

Aliases :

ARF exchange factor; ARF nucleotide-binding site opener; ARNO; B2-1; B2-1/ARNO; CLM1; CLM2; CTC-273B12.8; CTH-1; CTS18; CTS18.1; Cyth1; Cyth2; CYTIP; cytoadhesin 1; cytohesin 1; cytohesin 2; cytohesin-1; Cytohesin-2; D17S811E; homolog of secretory protein SEC7; mKIAA4240; mSec7-1; mSec7-2; PH, SEC7 and coiled-coil domain-containing protein 1; PH, SEC7 and coiled-coil domain-containing protein 2; pleckstrin homology, Sec7 and coiled/coil domains 2 (cytohesin-2); pleckstrin homology, Sec7 and coiled-coil domains 1; pleckstrin homology, Sec7 and coiled-coil domains 2; pleckstrin homology, Sec7 and coiled-coil domains 2 (cytohesin-2); Protein ARNO; PSCD1; Pscd2; PSCD2L; SEC7; SEC7 homolog A; SEC7 homolog B; SEC7 homolog B2-1; Sec7b; SEC7L; Sec7p-L; Sec7p-like