Lamin B2 Monoclonal Antibody (LN43) | Invitrogen MA1-06104 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Lamin B2 Monoclonal Antibody (LN43)

catalog :

MA1-06104

quantity :

100 µL

price :

US 403.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

LN43

reactivity :

hamsters, Chinese hamsters, human, mouse, pigs , zebrafish , Xenopus laevis

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; hamsters; loading ...; fig s19a	Tajik A, Zhang Y, Wei F, Sun J, Jia Q, Zhou W, et al. Transcription upregulation via force-induced direct stretching of chromatin. Nat Mater. 2016;15:1287-1296 pubmed publisher
western blot; mouse	Zhou Y, Feng X, Koh D. Activation of cell death mediated by apoptosis-inducing factor due to the absence of poly(ADP-ribose) glycohydrolase. Biochemistry. 2011;50:2850-9 pubmed publisher
	Hopkins M, Feng X, Liu M, Parker L, Koh D. Inhibition of the transient receptor potential melastatin-2 channel causes increased DNA damage and decreased proliferation in breast adenocarcinoma cells. Int J Oncol. 2015;46:2267-76 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Lamin B2 Monoclonal Antibody (LN43)

Catalog # :

MA1-06104

Quantity :

100 µL

Price :

US 403.00

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Hamster, Human, Mouse, Porcine, Xenopus laevis, Zebrafish

Applications :

Flow Cytometry: 1:100-1:200, Immunocytochemistry: 1:200, Immunohistochemistry (Frozen): 1:100- 1:200, Western Blot: 1:100-1:1,000

Species :

Hamster, Human, Mouse, Porcine, Xenopus laevis, Zebrafish

Clone :

LN43

Isotype :

IgG1

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

Nuclear lamins form a network of intermediate-type filaments at the nucleoplasmic site of the nuclear membrane. Two main subtypes of nuclear lamins can be distinguished, i.e. A-type lamins and B-type lamins. The A-type lamins comprise a set of three proteins arising from the same gene by alternative splicing, i.e. lamin A, lamin C and lamin Adel 10, while the B-type lamins include two proteins arising from two distinct genes, i.e. lamin B1 and lamin B2. Recent evidence has revealed that mutations in A-type lamins give rise to a range of rare but dominant genetic disorders, including Emery-Dreifuss muscular dystrophy, dilated cardiomyopathy with conduction-system disease and Dunnigan-type familial partial lipodystrophy. In addition, the expression of A-type lamins coincides with cell differentiation and as A-type lamins specifically interact with chromatin, a role in the regulation of differential gene expression has been suggested for A-type lamins.

Immunogen :

Detergent insoluble fraction of potoroo cell line PtK1.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:100-1:200, Immunocytochemistry: 1:200, Immunohistochemistry (Frozen): 1:100- 1:200, Western Blot: 1:100-1:1,000

Aliases :

EPM9; fc15d06; im:7142331; LAMB2; lamin; lamin A/C; lamin B2; lamin B2 S homeolog; lamin B3; lamin-B2; Lamin-L(II); LMN2; LMNA; lmnb2; lmnb2.S; lmnb2-a; lmnb2-b; MGC2721; RGD1563803; unnamed protein product; wu:fb94e05; wu:fb95e12; wu:fc15d06; wu:fc49h03; XELAEV_18009631mg

more info or order :

Invitrogen product webpage