Lamin A/C Monoclonal Antibody (131C3) | Invitrogen MA1-06102 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Lamin A/C Monoclonal Antibody (131C3)

catalog :

MA1-06102

quantity :

100 µg

price :

US 413.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

131C3

reactivity :

Chinese hamsters, human, mouse, rat, dogs, bovine, domestic sheep

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:200; loading ...; fig 4	Hatch E, Hetzer M. Nuclear envelope rupture is induced by actin-based nucleus confinement. J Cell Biol. 2016;215:27-36 pubmed
western blot; rat western blot; human	Shulga N, Hoek J, Pastorino J. Elevated PTEN levels account for the increased sensitivity of ethanol-exposed cells to tumor necrosis factor-induced cytotoxicity. J Biol Chem. 2005;280:9416-24 pubmed

image

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product information

Product Type :

Antibody

Product Name :

Lamin A/C Monoclonal Antibody (131C3)

Catalog # :

MA1-06102

Quantity :

100 µg

Price :

US 413.00

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Bovine, Canine, Hamster, Human, Mouse, Ovine, Rat

Applications :

ChIP assay: 2.5 µg/10^6 cells, Flow Cytometry: 1:100-1:200, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Frozen): 1:100-1:200, Western Blot: 1:100-1:1,000

Species :

Bovine, Canine, Hamster, Human, Mouse, Ovine, Rat

Clone :

131C3

Isotype :

IgG1

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

Lamins are a class of intermediate filament proteins that form a matrix on the inner surface of the nuclear envelope. These proteins are found in many different cell types in three different forms (A, B, and C). Lamins A and C are alternatively spliced versions of the LMNA gene. The LMNA gene has been linked to many disorders of the muscular system, nervous system, and the fat distributions systems including: Emery-Dreifuss muscular dystrophy, Dunnigan-type familial partial lipodystrophy (FPLD), limb-girdle muscular dystrophy (LGMD1B), dilated cardiomyopathy (CMD1A), axonal neuropathy (Charcot-Marie-Tooth disease; CMT2B1), and mandibuloacral dysplasia (MAD).

Immunogen :

Purified rat liver lamin.

Format :

Liquid

Applications w/Dilutions :

ChIP assay: 2.5 µg/10^6 cells, Flow Cytometry: 1:100-1:200, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Frozen): 1:100-1:200, Western Blot: 1:100-1:1,000

Aliases :

70 kDa lamin; cb948; CDCD1; CDDC; CMD1A; CMT2B1; Dhe; EMD2; FPL; FPLD; FPLD2; HGPS; I79_009616; IDC; lamin; lamin A; lamin A/C; lamin A/C L homeolog; lamin A/C-like 1; Lamin A+C mutant; Lamin AC; lamin a-c; lamin C; lamin C2; lamin-A; Lamin-A/C; LDP1; LFP; LGMD1B; LMN1; lmna; LMNA protein; lmna.L; lmna-A; LMNC; LMNL1; mutant 453W; Mutant lamin A/C; nuclear intermediate filament protein; nuclear lamin A; prelamin-A/C; PRO1; progerin mutant; Renal carcinoma antigen NY-REN-32; RP11-54H19.1; unnamed protein product; wu:fk66d12; XELAEV_18040808mg

more info or order :

Invitrogen product webpage