Cytohesin 2 Monoclonal Antibody (10A12) | Invitrogen MA1-061 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Cytohesin 2 Monoclonal Antibody (10A12)

catalog :

MA1-061

quantity :

100 ug

price :

US 399.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

10A12

The same clone is also sold as:

Abcam: ab2728
Novus Biologicals: NBP2-22514

reactivity :

human, mouse

application :

immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

citations: 1

Reference
Garceau V, Houle M, Chouinard F, Gagnon S, Harbour D, Naccache P, et al. Characterization of cytohesin-1 monoclonal antibodies: expression in neutrophils and during granulocytic maturation of HL-60 cells. J Immunol Methods. 2001;249:121-36 pubmed

product information

Product Type :

Antibody

Product Name :

Cytohesin 2 Monoclonal Antibody (10A12)

Catalog # :

MA1-061

Quantity :

100 ug

Price :

US 399.00

Clonality :

Monoclonal

Purity :

PEG precipitation

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 1:20, Immunohistochemistry (Paraffin): 1:25-1:200, Immunoprecipitation: Assay-dependent

Species :

Human, Mouse

Clone :

10A12

Isotype :

IgG1

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6 and is 83% homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene.

Immunogen :

Purified, His-tagged cytohesin-2.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:20, Immunohistochemistry (Paraffin): 1:25-1:200, Immunoprecipitation: Assay-dependent

Aliases :

ARF exchange factor; ARF nucleotide binding site opener; ARF nucleotide-binding site opener; ARNO; CLM2; CTC-273B12.8; CTS18; CTS18.1; Cyth2; cytohesin 2; cytohesin-2; mSec7-2; PH, SEC7 and coiled-coil domain-containing protein 2; pleckstrin homology, Sec7 and coiled/coil domains 2 (cytohesin-2); pleckstrin homology, Sec7 and coiled-coil domains 2; pleckstrin homology, Sec7 and coiled-coil domains 2 (cytohesin-2); Protein ARNO; PSCD2; PSCD2L; Sec7; SEC7 homolog B; Sec7b; SEC7L; Sec7p-L; Sec7p-like