CETP Monoclonal Antibody (ATM192) | Invitrogen MA1-050 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CETP Monoclonal Antibody (ATM192)

catalog :

MA1-050

quantity :

100 µL

price :

US 412.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

ATM192

reactivity :

human, domestic rabbit

application :

western blot, ELISA, immunocytochemistry, immunoprecipitation

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 2	Reyes Soffer G, Millar J, Ngai C, Jumes P, Coromilas E, Asztalos B, et al. Cholesteryl Ester Transfer Protein Inhibition With Anacetrapib Decreases Fractional Clearance Rates of High-Density Lipoprotein Apolipoprotein A-I and Plasma Cholesteryl Ester Transfer Protein. Arterioscler Thromb Vasc Biol. 2016;36:994-1002 pubmed publisher
	Thomas A, Smith A, Cumming R, Jones C, Thomas R, Pleasants K, et al. Mouse monoclonal antipeptide antibodies specific for cholesteryl ester transfer protein (CETP). Hybridoma. 1996;15:359-64 pubmed

image

image 1 :

Immunofluorescent analysis of CETP in HepG2 Cells. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with a CETP monoclonal antibody (Product # MA1-050) at a dilution of 1:20 overnight at 4 C, washed with PBS and incubated with a DyLight-488 conjugated secondary antibody (Product # 35503). CETP staining (green), F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Images were taken at 60X magnification.

image 2 :

product information

Product Type :

Antibody

Product Name :

CETP Monoclonal Antibody (ATM192)

Catalog # :

MA1-050

Quantity :

100 µL

Price :

US 412.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Rabbit

Applications :

ELISA: Assay-dependent, Immunocytochemistry: 1:20, Immunoprecipitation: Assay-dependent, Western Blot: 1-3 µg/mL

Species :

Human, Rabbit

Clone :

ATM192

Isotype :

IgG1

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

It has been proposed that high density lipoproteins (HDLs) function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. This mechanism, referred to as reverse cholesterol transport, is physiologically important because it maintains systemic cholesterol levels. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to accelerate specifically the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions, it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. CETP has an important role in reverse cholesterol transport and shaping and affecting the composition of plasma lipoproteins. In general elevated levels of CETP have been associated with increased risk of coronary heart disease.

Immunogen :

Synthetic peptide corresponding to residues C D(149) S G R V R T D A P D(159) of human CETP protein.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Immunocytochemistry: 1:20, Immunoprecipitation: Assay-dependent, Western Blot: 1-3 µg/mL

Aliases :

BPI fold containing family F; BPIFF; CETP; Cholesteryl ester transfer protein; cholesteryl ester transfer protein plasma; cholesteryl ester transfer protein, plasma; HDLCQ10; Lipid transfer protein I

more info or order :

Invitrogen product webpage