PSD-95 Monoclonal Antibody (6G6-1C9) | Invitrogen MA1-045 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PSD-95 Monoclonal Antibody (6G6-1C9)

catalog :

MA1-045

quantity :

100 µL

price :

US 449.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6G6-1C9

reactivity :

African green monkey, human, mouse, rat, roundworm

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, chromatin immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 310

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; mouse; loading ...; fig s4q western blot; mouse; loading ...; fig s3d	Swarnkar S, Avchalumov Y, Espadas I, Grinman E, Liu X, Raveendra B, et al. Molecular motor protein KIF5C mediates structural plasticity and long-term memory by constraining local translation. Cell Rep. 2021;36:109369 pubmed publisher
immunohistochemistry; rat; loading ...; fig 4a	Doré K, Carrico Z, Alfonso S, Marino M, Koymans K, Kessels H, et al. PSD-95 protects synapses from β-amyloid. Cell Rep. 2021;35:109194 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig s4j	Zhang X, Wang R, Hu D, Sun X, Fujioka H, Lundberg K, et al. Oligodendroglial glycolytic stress triggers inflammasome activation and neuropathology in Alzheimer's disease. Sci Adv. 2020;6: pubmed publisher
western blot; mouse; 1:300; loading ...; fig 1d	Chen C, Soto G, Dumrongprechachan V, BANNON N, Kang S, Kozorovitskiy Y, et al. Pathway-specific dysregulation of striatal excitatory synapses by LRRK2 mutations. elife. 2020;9: pubmed publisher
immunohistochemistry; human; 1:200; loading ...; fig 2d	Zhong X, Harris G, Smirnova L, Zufferey V, Sá R, Baldino Russo F, et al. Antidepressant Paroxetine Exerts Developmental Neurotoxicity in an iPSC-Derived 3D Human Brain Model. Front Cell Neurosci. 2020;14:25 pubmed publisher
western blot; mouse; loading ...; fig 5a	Li J, Chiu J, Ramanjulu M, Blass B, Pratico D. A pharmacological chaperone improves memory by reducing Aβ and tau neuropathology in a mouse model with plaques and tangles. Mol Neurodegener. 2020;15:1 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 5c western blot; mouse; 1:200; loading ...; fig 5a	di Meco A, Pratico D. Early-life exposure to high-fat diet influences brain health in aging mice. Aging Cell. 2019;18:e13040 pubmed publisher
immunocytochemistry; mouse; loading ...; fig 1d western blot; mouse; loading ...; fig s1j	Awasthi A, Ramachandran B, Ahmed S, Benito E, Shinoda Y, Nitzan N, et al. Synaptotagmin-3 drives AMPA receptor endocytosis, depression of synapse strength, and forgetting. Science. 2019;363: pubmed publisher
immunocytochemistry; mouse; 1:500; loading ...; fig s2g	Tanabe Y, Naito Y, Vasuta C, Lee A, Soumounou Y, Linhoff M, et al. IgSF21 promotes differentiation of inhibitory synapses via binding to neurexin2?. Nat Commun. 2017;8:408 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 2a	Wilkinson B, Li J, Coba M. Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling. Sci Rep. 2017;7:5272 pubmed publisher
western blot; mouse; loading ...; fig 1a	Frank R, Zhu F, Komiyama N, Grant S. Hierarchical organization and genetically separable subfamilies of PSD95 postsynaptic supercomplexes. J Neurochem. 2017;142:504-511 pubmed publisher
western blot; mouse; loading ...; fig 2d	Bobo Jiménez V, Delgado Esteban M, Angibaud J, Sánchez Morán I, de la Fuente A, Yajeya J, et al. APC/CCdh1-Rock2 pathway controls dendritic integrity and memory. Proc Natl Acad Sci U S A. 2017;114:4513-4518 pubmed publisher
immunohistochemistry; mouse; loading ...; fig 5c western blot; mouse; fig 5a	Li J, Barrero C, Merali S, Pratico D. Five lipoxygenase hypomethylation mediates the homocysteine effect on Alzheimer's phenotype. Sci Rep. 2017;7:46002 pubmed publisher
immunocytochemistry; rat; 1:200; loading ...; fig 3e western blot; rat; 1:2000; loading ...; fig 3b	Behnke J, Cheedalla A, Bhatt V, Bhat M, Teng S, Palmieri A, et al. Neuropeptide VGF Promotes Maturation of Hippocampal Dendrites That Is Reduced by Single Nucleotide Polymorphisms. Int J Mol Sci. 2017;18: pubmed publisher
immunocytochemistry; mouse; 1:150; loading ...; fig 5e	Ripamonti S, Ambrozkiewicz M, Guzzi F, Gravati M, Biella G, Bormuth I, et al. Transient oxytocin signaling primes the development and function of excitatory hippocampal neurons. elife. 2017;6: pubmed publisher
immunohistochemistry - frozen section; mouse; 1:500; fig 4a	Zhu G, Briz V, Seinfeld J, Liu Y, Bi X, Baudry M. Calpain-1 deletion impairs mGluR-dependent LTD and fear memory extinction. Sci Rep. 2017;7:42788 pubmed publisher
immunocytochemistry; rat; 1:1000; loading ...; fig 6f	Kim S, Im S, Oh S, Jeong S, Yoon E, Lee C, et al. Anisotropically organized three-dimensional culture platform for reconstruction of a hippocampal neural network. Nat Commun. 2017;8:14346 pubmed publisher
western blot; mouse; loading ...; fig s1b	Ugun Klusek A, Tatham M, Elkharaz J, Constantin Teodosiu D, Lawler K, Mohamed H, et al. Continued 26S proteasome dysfunction in mouse brain cortical neurons impairs autophagy and the Keap1-Nrf2 oxidative defence pathway. Cell Death Dis. 2017;8:e2531 pubmed publisher
western blot; mouse; loading ...; fig 4b	Sabanov V, Braat S, D Andrea L, Willemsen R, Zeidler S, Rooms L, et al. Impaired GABAergic inhibition in the hippocampus of Fmr1 knockout mice. Neuropharmacology. 2017;116:71-81 pubmed publisher
western blot; rat; 1:800; loading ...; fig 5a	Marco E, Ballesta J, Irala C, Hernández M, Serrano M, Mela V, et al. Sex-dependent influence of chronic mild stress (CMS) on voluntary alcohol consumption; study of neurobiological consequences. Pharmacol Biochem Behav. 2017;152:68-80 pubmed publisher
immunocytochemistry; human; 1:500; fig 4a	Begum A, Aguilar J, Elias L, Hong Y. Silver nanoparticles exhibit coating and dose-dependent neurotoxicity in glutamatergic neurons derived from human embryonic stem cells. Neurotoxicology. 2016;57:45-53 pubmed publisher
immunohistochemistry - frozen section; rat; loading ...; fig 4b	Wang W, Trieu B, Palmer L, Jia Y, Pham D, Jung K, et al. A Primary Cortical Input to Hippocampus Expresses a Pathway-Specific and Endocannabinoid-Dependent Form of Long-Term Potentiation. Eneuro. 2016;3: pubmed publisher
immunocytochemistry; rat; loading ...; fig 3	Li Y, Chang L, Song Y, Gao X, Roselli F, Liu J, et al. Astrocytic GluN2A and GluN2B Oppose the Synaptotoxic Effects of Amyloid-?1-40 in Hippocampal Cells. J Alzheimers Dis. 2016;54:135-48 pubmed publisher
immunohistochemistry; rat; 1:1000; loading ...; fig 1a	Wang W, Kantorovich S, Babayan A, Hou B, Gall C, Lynch G. Estrogen's Effects on Excitatory Synaptic Transmission Entail Integrin and TrkB Transactivation and Depend Upon ?1-integrin function. Neuropsychopharmacology. 2016;41:2723-32 pubmed publisher
western blot; mouse; 1:1000; fig s4 western blot; rat; fig 2	Reinhard J, Kriz A, Galic M, Angliker N, Rajalu M, Vogt K, et al. The calcium sensor Copine-6 regulates spine structural plasticity and learning and memory. Nat Commun. 2016;7:11613 pubmed publisher
immunocytochemistry; mouse; 1:200; fig 3	Gibon J, Unsain N, Gamache K, Thomas R, de León A, Johnstone A, et al. The X-linked inhibitor of apoptosis regulates long-term depression and learning rate. FASEB J. 2016;30:3083-90 pubmed publisher
immunocytochemistry; mouse; 1:50; fig 2	Xia M, Zhu S, Shevelkin A, Ross C, Pletnikov M. DISC1, astrocytes and neuronal maturation: a possible mechanistic link with implications for mental disorders. J Neurochem. 2016;138:518-24 pubmed publisher
western blot; mouse; 1:5000; fig 6	Matchynski Franks J, Susick L, Schneider B, Perrine S, Conti A. Impaired Ethanol-Induced Sensitization and Decreased Cannabinoid Receptor-1 in a Model of Posttraumatic Stress Disorder. PLoS ONE. 2016;11:e0155759 pubmed publisher
immunohistochemistry - frozen section; mouse; fig 4	Park J, Yu Y, Zhou C, Li K, Wang D, Chang E, et al. Central Mechanisms Mediating Thrombospondin-4-induced Pain States. J Biol Chem. 2016;291:13335-48 pubmed publisher
immunocytochemistry; mouse; 1:1000; fig 3	Buren C, Tu G, Parsons M, Sepers M, Raymond L. Influence of cortical synaptic input on striatal neuronal dendritic arborization and sensitivity to excitotoxicity in corticostriatal coculture. J Neurophysiol. 2016;116:380-90 pubmed publisher
western blot; mouse; 1:3000; fig 7	Frank R, Komiyama N, Ryan T, Zhu F, O Dell T, Grant S. NMDA receptors are selectively partitioned into complexes and supercomplexes during synapse maturation. Nat Commun. 2016;7:11264 pubmed publisher
immunocytochemistry; rat; 1:1000; fig 4	Lauterborn J, Kramar E, Rice J, Babayan A, Cox C, Karsten C, et al. Cofilin Activation Is Temporally Associated with the Cessation of Growth in the Developing Hippocampus. Cereb Cortex. 2017;27:2640-2651 pubmed publisher
immunocytochemistry; rat; 1:2000; fig 5	Kos A, Wanke K, Gioio A, Martens G, Kaplan B, Aschrafi A. Monitoring mRNA Translation in Neuronal Processes Using Fluorescent Non-Canonical Amino Acid Tagging. J Histochem Cytochem. 2016;64:323-33 pubmed publisher
immunocytochemistry; mouse; fig 1	Zhang Q, Gao X, Li C, Feliciano C, Wang D, Zhou D, et al. Impaired Dendritic Development and Memory in Sorbs2 Knock-Out Mice. J Neurosci. 2016;36:2247-60 pubmed publisher
western blot; mouse; fig 2	Kim G, LujÃ¡n R, Schwenk J, Kelley M, Aguado C, Watanabe M, et al. Membrane palmitoylated protein 2 is a synaptic scaffold protein required for synaptic SK2-containing channel function. elife. 2016;5: pubmed publisher
immunohistochemistry - frozen section; mouse; 1:100; fig 4	Venugopalan P, Wang Y, Nguyen T, Huang A, Muller K, Goldberg J. Transplanted neurons integrate into adult retinas and respond to light. Nat Commun. 2016;7:10472 pubmed publisher
immunoprecipitation; human; fig 5 western blot; human; fig 5	Wee K, Tan F, Cheong Y, Khanna S, Low C. Ontogenic Profile and Synaptic Distribution of GluN3 Proteins in the Rat Brain and Hippocampal Neurons. Neurochem Res. 2016;41:290-7 pubmed publisher
western blot; mouse	Mircsof D, LangouÃ«t M, Rio M, Moutton S, Siquier Pernet K, Bole Feysot C, et al. Mutations in NONO lead to syndromic intellectual disability and inhibitory synaptic defects. Nat Neurosci. 2015;18:1731-6 pubmed publisher
immunohistochemistry; human; fig 2	Hjelm B, Rollins B, Mamdani F, Lauterborn J, Kirov G, Lynch G, et al. Evidence of Mitochondrial Dysfunction within the Complex Genetic Etiology of Schizophrenia. Mol Neuropsychiatry. 2015;1:201-19 pubmed publisher
immunocytochemistry; mouse; fig 4	Mayanagi T, Yasuda H, Sobue K. PSD-Zip70 Deficiency Causes Prefrontal Hypofunction Associated with Glutamatergic Synapse Maturation Defects by Dysregulation of Rap2 Activity. J Neurosci. 2015;35:14327-40 pubmed publisher
western blot; rat; 1:2000; fig 5	Briz V, Liu Y, Zhu G, Bi X, Baudry M. A novel form of synaptic plasticity in field CA3 of hippocampus requires GPER1 activation and BDNF release. J Cell Biol. 2015;210:1225-37 pubmed publisher
immunohistochemistry - paraffin section; mouse; fig 4,5	Gingras S, Earls L, Howell S, Smeyne R, Zakharenko S, Pelletier S. SCYL2 Protects CA3 Pyramidal Neurons from Excitotoxicity during Functional Maturation of the Mouse Hippocampus. J Neurosci. 2015;35:10510-22 pubmed publisher
western blot; mouse	Underhill S, Wheeler D, Amara S. Differential regulation of two isoforms of the glial glutamate transporter EAAT2 by DLG1 and CaMKII. J Neurosci. 2015;35:5260-70 pubmed publisher
immunocytochemistry; mouse; 1:2000; loading ...; fig 1e	Thibault D, GiguÃ¨re N, Loustalot F, Bourque M, Ducrot C, El Mestikawy S, et al. Homeostatic regulation of excitatory synapses on striatal medium spiny neurons expressing the D2 dopamine receptor. Brain Struct Funct. 2016;221:2093-107 pubmed publisher
immunohistochemistry; roundworm	Von Stetina S, Mango S. PAR-6, but not E-cadherin and Î²-integrin, is necessary for epithelial polarization in C. elegans. Dev Biol. 2015;403:5-14 pubmed publisher
immunohistochemistry - frozen section; rat; 1:500	Briz V, Zhu G, Wang Y, Liu Y, Avetisyan M, Bi X, et al. Activity-dependent rapid local RhoA synthesis is required for hippocampal synaptic plasticity. J Neurosci. 2015;35:2269-82 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:500	Zhu G, Liu Y, Wang Y, Bi X, Baudry M. Different patterns of electrical activity lead to long-term potentiation by activating different intracellular pathways. J Neurosci. 2015;35:621-33 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:500	Zhu G, Li J, He L, Wang X, Hong X. MPTP-induced changes in hippocampal synaptic plasticity and memory are prevented by memantine through the BDNF-TrkB pathway. Br J Pharmacol. 2015;172:2354-68 pubmed publisher
immunohistochemistry - frozen section; rat	Lee J, Lee E, Lee H. Hypothalamic, feeding/arousal-related peptidergic projections to the paraventricular thalamic nucleus in the rat. Brain Res. 2015;1598:97-113 pubmed publisher
immunocytochemistry; rat; 1:500	Peng X, Hughes E, Moscato E, Parsons T, Dalmau J, Balice Gordon R. Cellular plasticity induced by anti-Î±-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor encephalitis antibodies. Ann Neurol. 2015;77:381-98 pubmed publisher
immunocytochemistry; mouse; 1:1000	Beccano Kelly D, Kuhlmann N, Tatarnikov I, Volta M, Munsie L, Chou P, et al. Synaptic function is modulated by LRRK2 and glutamate release is increased in cortical neurons of G2019S LRRK2 knock-in mice. Front Cell Neurosci. 2014;8:301 pubmed publisher
immunocytochemistry; rat; 1:1000; loading ...; fig 6 western blot; mouse; 1:1000; loading ...; fig 2	Kang Y, Ge Y, Cassidy R, Lam V, Luo L, Moon K, et al. A combined transgenic proteomic analysis and regulated trafficking of neuroligin-2. J Biol Chem. 2014;289:29350-64 pubmed publisher
western blot; human; 1:7000	Whitfield D, Vallortigara J, Alghamdi A, Howlett D, Hortobagyi T, Johnson M, et al. Assessment of ZnT3 and PSD95 protein levels in Lewy body dementias and Alzheimer's disease: association with cognitive impairment. Neurobiol Aging. 2014;35:2836-2844 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:200; fig 5	Tyzack G, Sitnikov S, Barson D, Adams Carr K, Lau N, Kwok J, et al. Astrocyte response to motor neuron injury promotes structural synaptic plasticity via STAT3-regulated TSP-1 expression. Nat Commun. 2014;5:4294 pubmed publisher
immunohistochemistry; mouse	Poguzhelskaya E, Artamonov D, Bolshakova A, Vlasova O, Bezprozvanny I. Simplified method to perform CLARITY imaging. Mol Neurodegener. 2014;9:19 pubmed publisher
immunocytochemistry; rat; fig 5	Louros S, Hooks B, Litvina L, Carvalho A, Chen C. A role for stargazin in experience-dependent plasticity. Cell Rep. 2014;7:1614-1625 pubmed publisher
western blot; mouse; 1:1000	Nikitczuk J, Patil S, Matikainen Ankney B, Scarpa J, Shapiro M, Benson D, et al. N-cadherin regulates molecular organization of excitatory and inhibitory synaptic circuits in adult hippocampus in vivo. Hippocampus. 2014;24:943-962 pubmed publisher
immunocytochemistry; human; 1:1000	Gomis Rüth S, Stiess M, Wierenga C, Meyn L, Bradke F. Single-cell axotomy of cultured hippocampal neurons integrated in neuronal circuits. Nat Protoc. 2014;9:1028-37 pubmed publisher
immunohistochemistry; mouse; 1:2000	Maras P, Molet J, Chen Y, Rice C, Ji S, Solodkin A, et al. Preferential loss of dorsal-hippocampus synapses underlies memory impairments provoked by short, multimodal stress. Mol Psychiatry. 2014;19:811-22 pubmed publisher
western blot; mouse; 1:500	Gladding C, Fan J, Zhang L, Wang L, Xu J, Li E, et al. Alterations in STriatal-Enriched protein tyrosine Phosphatase expression, activation, and downstream signaling in early and late stages of the YAC128 Huntington's disease mouse model. J Neurochem. 2014;130:145-59 pubmed publisher
western blot; rat; 1:1000	Colciaghi F, Finardi A, Nobili P, Locatelli D, Spigolon G, Battaglia G. Progressive brain damage, synaptic reorganization and NMDA activation in a model of epileptogenic cortical dysplasia. PLoS ONE. 2014;9:e89898 pubmed publisher
immunohistochemistry; rat; 1:400	Aira Z, Buesa I, Rada D, Gomez Esteban J, Azkue J. Coupling of serotonergic input to NMDA receptor-phosphorylation following peripheral nerve injury via rapid, synaptic up-regulation of ND2. Exp Neurol. 2014;255:86-95 pubmed publisher
immunohistochemistry; rat; 1:1000	Cox C, Rex C, Palmer L, Babayan A, Pham D, Corwin S, et al. A map of LTP-related synaptic changes in dorsal hippocampus following unsupervised learning. J Neurosci. 2014;34:3033-41 pubmed publisher
immunohistochemistry; rat; 1:200	del Pino I, Koch D, Schemm R, Qualmann B, Betz H, Paarmann I. Proteomic analysis of glycine receptor ? subunit (GlyR?)-interacting proteins: evidence for syndapin I regulating synaptic glycine receptors. J Biol Chem. 2014;289:11396-409 pubmed publisher
immunocytochemistry; rat; 1:1000	Itakura M, Watanabe I, Sugaya T, Takahashi M. Direct association of the unique C-terminal tail of transmembrane AMPA receptor regulatory protein ?-8 with calcineurin. FEBS J. 2014;281:1366-78 pubmed publisher
immunohistochemistry - frozen section; rat; 1:500	Wang Y, Zhu G, Briz V, Hsu Y, Bi X, Baudry M. A molecular brake controls the magnitude of long-term potentiation. Nat Commun. 2014;5:3051 pubmed publisher
immunocytochemistry; mouse; 1:1000	Parsons M, Kang R, Buren C, Dau A, Southwell A, Doty C, et al. Bidirectional control of postsynaptic density-95 (PSD-95) clustering by Huntingtin. J Biol Chem. 2014;289:3518-28 pubmed publisher
immunocytochemistry; rat western blot; rat	Wang Y, Briz V, Chishti A, Bi X, Baudry M. Distinct roles for ?-calpain and m-calpain in synaptic NMDAR-mediated neuroprotection and extrasynaptic NMDAR-mediated neurodegeneration. J Neurosci. 2013;33:18880-92 pubmed publisher
western blot; mouse; 1:500	Dau A, Gladding C, Sepers M, Raymond L. Chronic blockade of extrasynaptic NMDA receptors ameliorates synaptic dysfunction and pro-death signaling in Huntington disease transgenic mice. Neurobiol Dis. 2014;62:533-42 pubmed publisher
immunocytochemistry; rat	Yam P, Pincus Z, Gupta G, Bashkurov M, Charron F, Pelletier L, et al. N-cadherin relocalizes from the periphery to the center of the synapse after transient synaptic stimulation in hippocampal neurons. PLoS ONE. 2013;8:e79679 pubmed publisher
immunohistochemistry; human; 1:75	Leuba G, Vernay A, Kraftsik R, Tardif E, Riederer B, Savioz A. Pathological reorganization of NMDA receptors subunits and postsynaptic protein PSD-95 distribution in Alzheimer's disease. Curr Alzheimer Res. 2014;11:86-96 pubmed
immunocytochemistry; rat; 1:4000	Andres A, Regev L, Phi L, Seese R, Chen Y, Gall C, et al. NMDA receptor activation and calpain contribute to disruption of dendritic spines by the stress neuropeptide CRH. J Neurosci. 2013;33:16945-60 pubmed publisher
immunocytochemistry; rat; 1:500	Aujla P, Huntley G. Early postnatal expression and localization of matrix metalloproteinases-2 and -9 during establishment of rat hippocampal synaptic circuitry. J Comp Neurol. 2014;522:1249-63 pubmed publisher
western blot; human; 1:200	Sowa Kucma M, Szewczyk B, Sadlik K, Piekoszewski W, Trela F, Opoka W, et al. Zinc, magnesium and NMDA receptor alterations in the hippocampus of suicide victims. J Affect Disord. 2013;151:924-31 pubmed publisher
immunohistochemistry; rat	Petoukhov E, Fernando S, Mills F, Shivji F, Hunter D, Krieger C, et al. Activity-dependent secretion of progranulin from synapses. J Cell Sci. 2013;126:5412-21 pubmed publisher
immunohistochemistry; rat; 1:1000	Wang X, Lippi G, Carlson D, Berg D. Activation of ?7-containing nicotinic receptors on astrocytes triggers AMPA receptor recruitment to glutamatergic synapses. J Neurochem. 2013;127:632-43 pubmed publisher
immunocytochemistry; mouse; 1:200	Aoto J, Martinelli D, Malenka R, Tabuchi K, Sudhof T. Presynaptic neurexin-3 alternative splicing trans-synaptically controls postsynaptic AMPA receptor trafficking. Cell. 2013;154:75-88 pubmed publisher
immunocytochemistry; mouse; 1:200	Alder J, Kallman S, Palmieri A, Khadim F, Ayer J, Kumar S, et al. Neuropeptide orphanin FQ inhibits dendritic morphogenesis through activation of RhoA. Dev Neurobiol. 2013;73:769-84 pubmed publisher
immunohistochemistry; mouse	Cho K, Haque M, Wang J, Yu M, Hao Y, Qiu S, et al. Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors. PLoS Genet. 2013;9:e1003555 pubmed publisher
western blot; human; 1:1000	Finardi A, Colciaghi F, Castana L, Locatelli D, Marras C, Nobili P, et al. Long-duration epilepsy affects cell morphology and glutamatergic synapses in type IIB focal cortical dysplasia. Acta Neuropathol. 2013;126:219-35 pubmed publisher
immunohistochemistry; mouse; 1:200	Zabouri N, Haverkamp S. Calcium channel-dependent molecular maturation of photoreceptor synapses. PLoS ONE. 2013;8:e63853 pubmed publisher
western blot; rat	Weng L, Lin Y, Li A, Wang C, Yan S, Sun M, et al. Loss of Ahi1 affects early development by impairing BM88/Cend1-mediated neuronal differentiation. J Neurosci. 2013;33:8172-84 pubmed publisher
immunoprecipitation; rat; 2 ug western blot; rat; 1:500	Yoshioka T, Hagiwara A, Hida Y, Ohtsuka T. Vangl2, the planar cell polarity protein, is complexed with postsynaptic density protein PSD-95 [corrected]. FEBS Lett. 2013;587:1453-9 pubmed publisher
immunohistochemistry; mouse; 1:800; fig 6	Vogel Ciernia A, Matheos D, Barrett R, Kramar E, Azzawi S, Chen Y, et al. The neuron-specific chromatin regulatory subunit BAF53b is necessary for synaptic plasticity and memory. Nat Neurosci. 2013;16:552-61 pubmed publisher
immunohistochemistry; rat	Oh J, Kwon A, Jo A, Kim H, Goo Y, Lee J, et al. Activity-dependent synaptic localization of processing bodies and their role in dendritic structural plasticity. J Cell Sci. 2013;126:2114-23 pubmed publisher
immunohistochemistry; mouse	Molica F, Burger F, Thomas A, Staub C, Tailleux A, Staels B, et al. Endogenous cannabinoid receptor CB1 activation promotes vascular smooth-muscle cell proliferation and neointima formation. J Lipid Res. 2013;54:1360-8 pubmed publisher
immunocytochemistry; mouse; 1:500	Ibi D, Nagai T, Nakajima A, Mizoguchi H, Kawase T, Tsuboi D, et al. Astroglial IFITM3 mediates neuronal impairments following neonatal immune challenge in mice. Glia. 2013;61:679-93 pubmed publisher
immunohistochemistry; rat; 1:500	Pettem K, Yokomaku D, Takahashi H, Ge Y, Craig A. Interaction between autism-linked MDGAs and neuroligins suppresses inhibitory synapse development. J Cell Biol. 2013;200:321-36 pubmed publisher
western blot; rat; 1:10000	Mizuno M, Kato D, Kanamori T, Toyoda T, Suzuki T, Ojika K, et al. Phosphorylation of collapsin response mediator protein-2 regulates its localization and association with hippocampal cholinergic neurostimulating peptide precursor in the hippocampus. Neurosci Lett. 2013;535:122-7 pubmed publisher
western blot; rat; 0.5 ug/ml	Borlikova G, Trejo M, Mably A, Mc Donald J, Sala Frigerio C, Regan C, et al. Alzheimer brain-derived amyloid ?-protein impairs synaptic remodeling and memory consolidation. Neurobiol Aging. 2013;34:1315-27 pubmed publisher
western blot; rat	Tanokashira D, Morita T, Hayashi K, Mayanagi T, Fukumoto K, Kubota Y, et al. Glucocorticoid suppresses dendritic spine development mediated by down-regulation of caldesmon expression. J Neurosci. 2012;32:14583-91 pubmed publisher
immunocytochemistry; human; 1:400	Aira Z, Buesa I, Gallego M, Garcia del Caño G, Mendiable N, Mingo J, et al. Time-dependent cross talk between spinal serotonin 5-HT2A receptor and mGluR1 subserves spinal hyperexcitability and neuropathic pain after nerve injury. J Neurosci. 2012;32:13568-81 pubmed
immunocytochemistry; rat; 1:1000	Babayan A, Kramar E, Barrett R, Jafari M, Haettig J, Chen L, et al. Integrin dynamics produce a delayed stage of long-term potentiation and memory consolidation. J Neurosci. 2012;32:12854-61 pubmed publisher
immunocytochemistry; rat; 1:100	Maas C, Torres V, Altrock W, Leal Ortiz S, Wagh D, Terry Lorenzo R, et al. Formation of Golgi-derived active zone precursor vesicles. J Neurosci. 2012;32:11095-108 pubmed publisher
immunocytochemistry; rat; 1:500	Fuentes F, Zimmer D, Atienza M, Schottenfeld J, Penkala I, BALE T, et al. Protein tyrosine phosphatase PTP1B is involved in hippocampal synapse formation and learning. PLoS ONE. 2012;7:e41536 pubmed publisher
immunohistochemistry; mouse; 1:500 western blot; mouse; 1:1000	Carretón O, Giralt A, Torres Peraza J, Brito V, Lucas J, Gines S, et al. Age-dependent decline of motor neocortex but not hippocampal performance in heterozygous BDNF mice correlates with a decrease of cortical PSD-95 but an increase of hippocampal TrkB levels. Exp Neurol. 2012;237:335-45 pubmed publisher
immunocytochemistry; rat; 1:500	She K, Ferreira J, Carvalho A, Craig A. Glutamate binding to the GluN2B subunit controls surface trafficking of N-methyl-D-aspartate (NMDA) receptors. J Biol Chem. 2012;287:27432-45 pubmed publisher
immunocytochemistry; mouse; 1:1000	Milnerwood A, Kaufman A, Sepers M, Gladding C, Zhang L, Wang L, et al. Mitigation of augmented extrasynaptic NMDAR signaling and apoptosis in cortico-striatal co-cultures from Huntington's disease mice. Neurobiol Dis. 2012;48:40-51 pubmed publisher
immunohistochemistry; mouse; 1:1000	Lozada A, Wang X, Gounko N, Massey K, Duan J, Liu Z, et al. Glutamatergic synapse formation is promoted by ?7-containing nicotinic acetylcholine receptors. J Neurosci. 2012;32:7651-61 pubmed publisher
immunocytochemistry; rat; 1:2000	Okuno H, Akashi K, Ishii Y, Yagishita Kyo N, Suzuki K, Nonaka M, et al. Inverse synaptic tagging of inactive synapses via dynamic interaction of Arc/Arg3.1 with CaMKII?. Cell. 2012;149:886-98 pubmed publisher
western blot; mouse; 1:10000	Kato D, Mitake S, Mizuno M, Kanamori T, Suzuki T, Ojika K, et al. Co-localization of hippocampal cholinergic neurostimulating peptide precursor with collapsin response mediator protein-2 at presynaptic terminals in hippocampus. Neurosci Lett. 2012;517:92-7 pubmed publisher
western blot; mouse; 1:500	Gladding C, Sepers M, Xu J, Zhang L, Milnerwood A, Lombroso P, et al. Calpain and STriatal-Enriched protein tyrosine phosphatase (STEP) activation contribute to extrasynaptic NMDA receptor localization in a Huntington's disease mouse model. Hum Mol Genet. 2012;21:3739-52 pubmed publisher
western blot; mouse; 1:2500	Yadav R, Gupta S, Hillman B, Bhatt J, Stairs D, Dravid S. Deletion of glutamate delta-1 receptor in mouse leads to aberrant emotional and social behaviors. PLoS ONE. 2012;7:e32969 pubmed publisher
immunocytochemistry; mouse; 1:2000	Chen Y, Kramár E, Chen L, Babayan A, Andres A, Gall C, et al. Impairment of synaptic plasticity by the stress mediator CRH involves selective destruction of thin dendritic spines via RhoA signaling. Mol Psychiatry. 2013;18:485-96 pubmed publisher
western blot; human	Matsui C, Inoue E, Kakita A, Arita K, Deguchi Tawarada M, Togawa A, et al. Involvement of the ?-secretase-mediated EphA4 signaling pathway in synaptic pathogenesis of Alzheimer's disease. Brain Pathol. 2012;22:776-87 pubmed publisher
western blot; mouse; 1:2000	Shibasaki M, Kurokawa K, Mizuno K, Suzuki T, Ohkuma S. Actin dynamics in development of behavioral sensitization after withdrawal from long-term ethanol administration to mice. Alcohol Clin Exp Res. 2012;36:1385-96 pubmed publisher
western blot; mouse; 1:1000	Wilke S, Hall B, Antonios J, DeNardo L, Otto S, Yuan B, et al. NeuroD2 regulates the development of hippocampal mossy fiber synapses. Neural Dev. 2012;7:9 pubmed publisher
immunohistochemistry; mouse	Yamagata M, Sanes J. Transgenic strategy for identifying synaptic connections in mice by fluorescence complementation (GRASP). Front Mol Neurosci. 2012;5:18 pubmed publisher
immunohistochemistry; mouse; 1:100	Bagley E, Westbrook G. Short-term field stimulation mimics synaptic maturation of hippocampal synapses. J Physiol. 2012;590:1641-54 pubmed publisher
immunocytochemistry; mouse; 1:2000 western blot; mouse; 1:2000	Ettorre M, Lorenzetto E, Laperchia C, Baiguera C, Branca C, Benarese M, et al. Glutamatergic neurons induce expression of functional glutamatergic synapses in primary myotubes. PLoS ONE. 2012;7:e31451 pubmed publisher
immunocytochemistry; rat; 1:250	Andreae L, Fredj N, Burrone J. Independent vesicle pools underlie different modes of release during neuronal development. J Neurosci. 2012;32:1867-74 pubmed publisher
immunocytochemistry; mouse; 1:500	Takahashi H, Katayama K, Sohya K, Miyamoto H, Prasad T, Matsumoto Y, et al. Selective control of inhibitory synapse development by Slitrk3-PTP? trans-synaptic interaction. Nat Neurosci. 2012;15:389-98, S1-2 pubmed publisher
immunocytochemistry; rat	Peng X, Parsons T, Balice Gordon R. Determinants of synaptic strength vary across an axon arbor. J Neurophysiol. 2012;107:2430-41 pubmed publisher
immunoprecipitation; mouse western blot; mouse	Fan J, Gladding C, Wang L, Zhang L, Kaufman A, Milnerwood A, et al. P38 MAPK is involved in enhanced NMDA receptor-dependent excitotoxicity in YAC transgenic mouse model of Huntington disease. Neurobiol Dis. 2012;45:999-1009 pubmed publisher
immunocytochemistry; mouse; 1:100	Batcha A, Greferath U, Jobling A, Vessey K, Ward M, Nithianantharajah J, et al. Retinal dysfunction, photoreceptor protein dysregulation and neuronal remodelling in the R6/1 mouse model of Huntington's disease. Neurobiol Dis. 2012;45:887-96 pubmed publisher
immunoprecipitation; mouse	Briz V, Parkash J, Sánchez Redondo S, Prevot V, Suñol C. Allopregnanolone prevents dieldrin-induced NMDA receptor internalization and neurotoxicity by preserving GABA(A) receptor function. Endocrinology. 2012;153:847-60 pubmed publisher
immunohistochemistry - frozen section; rat; 1:100 immunohistochemistry; rat; 1:100	Chen A, Gössling E, Witkowski L, Bhindi A, Bauch C, Roussy G, et al. Regional and subcellular distribution of the receptor-targeting protein PIST in the rat central nervous system. J Comp Neurol. 2012;520:889-913 pubmed publisher
immunocytochemistry; mouse; 1:1000	She K, Craig A. NMDA receptors mediate synaptic competition in culture. PLoS ONE. 2011;6:e24423 pubmed publisher
immunohistochemistry; rat	Fan Y, Tang X, Vitriol E, Chen G, Zheng J. Actin capping protein is required for dendritic spine development and synapse formation. J Neurosci. 2011;31:10228-33 pubmed publisher
immunohistochemistry; rat; 1:200	Ling W, Chang L, Song Y, Lu T, Jiang Y, Li Y, et al. Immunolocalization of NR1, NR2A, and PSD-95 in rat hippocampal subregions during postnatal development. Acta Histochem. 2012;114:285-95 pubmed publisher
ELISA; human; 1:100 western blot; human; 1:100	Hiratsuka K, Momose A, Takagi N, Sasaki H, Yin S, Fujita M, et al. Neuronal expression, cytosolic localization, and developmental regulation of the organic solute carrier partner 1 in the mouse brain. Histochem Cell Biol. 2011;135:229-38 pubmed publisher
immunoprecipitation; human immunocytochemistry; human	Hida Y, Fukaya M, Hagiwara A, Deguchi Tawarada M, Yoshioka T, Kitajima I, et al. Prickle2 is localized in the postsynaptic density and interacts with PSD-95 and NMDA receptors in the brain. J Biochem. 2011;149:693-700 pubmed publisher
immunocytochemistry; mouse immunohistochemistry; mouse; 1:500	Sumida G, Stamer W. S1P? receptor regulation of sphingosine-1-phosphate effects on conventional outflow physiology. Am J Physiol Cell Physiol. 2011;300:C1164-71 pubmed publisher
immunocytochemistry; mouse immunohistochemistry; mouse; 1:500	Takahashi H, Arstikaitis P, Prasad T, Bartlett T, Wang Y, Murphy T, et al. Postsynaptic TrkC and presynaptic PTP? function as a bidirectional excitatory synaptic organizing complex. Neuron. 2011;69:287-303 pubmed publisher
immunocytochemistry; rat; 1:200	Sweet E, Previtera M, Fernandez J, Charych E, Tseng C, Kwon M, et al. PSD-95 alters microtubule dynamics via an association with EB3. J Neurosci. 2011;31:1038-47 pubmed publisher
western blot; rat	Voulalas P, Schetz J, Undieh A. Differential subcellular distribution of rat brain dopamine receptors and subtype-specific redistribution induced by cocaine. Mol Cell Neurosci. 2011;46:645-54 pubmed publisher
western blot; mouse; 1:1000	Shioda N, Beppu H, Fukuda T, Li E, Kitajima I, Fukunaga K. Aberrant calcium/calmodulin-dependent protein kinase II (CaMKII) activity is associated with abnormal dendritic spine morphology in the ATRX mutant mouse brain. J Neurosci. 2011;31:346-58 pubmed publisher
immunocytochemistry; rat; 1:250	Ripley B, Otto S, Tiglio K, Williams M, Ghosh A. Regulation of synaptic stability by AMPA receptor reverse signaling. Proc Natl Acad Sci U S A. 2011;108:367-72 pubmed publisher
immunocytochemistry; rat western blot; rat	Citri A, Bhattacharyya S, Ma C, Morishita W, Fang S, Rizo J, et al. Calcium binding to PICK1 is essential for the intracellular retention of AMPA receptors underlying long-term depression. J Neurosci. 2010;30:16437-52 pubmed publisher
immunohistochemistry; rat; 1:1,000	Chen L, Rex C, Pham D, Lynch G, Gall C. BDNF signaling during learning is regionally differentiated within hippocampus. J Neurosci. 2010;30:15097-101 pubmed publisher
immunocytochemistry; rat; 1:300	Nassirpour R, Bahima L, Lalive A, Lüscher C, Lujan R, Slesinger P. Morphine- and CaMKII-dependent enhancement of GIRK channel signaling in hippocampal neurons. J Neurosci. 2010;30:13419-30 pubmed publisher
immunocytochemistry; rat; 1:200 western blot; rat; 1:2000	Liu J, Chang L, Roselli F, Almeida O, Gao X, Wang X, et al. Amyloid-? induces caspase-dependent loss of PSD-95 and synaptophysin through NMDA receptors. J Alzheimers Dis. 2010;22:541-56 pubmed publisher
western blot; mouse	Fan J, Vasuta O, Zhang L, Wang L, George A, Raymond L. N-methyl-D-aspartate receptor subunit- and neuronal-type dependence of excitotoxic signaling through post-synaptic density 95. J Neurochem. 2010;115:1045-56 pubmed publisher
immunocytochemistry; rat; 1:200	Dodd J, Birch N, Waldvogel H, Christie D. Functional and immunocytochemical characterization of the creatine transporter in rat hippocampal neurons. J Neurochem. 2010;115:684-93 pubmed publisher
immunohistochemistry; mouse; 1:1000; fig 3	Chen L, Rex C, Babayan A, Kramar E, Lynch G, Gall C, et al. Physiological activation of synaptic Rac>PAK (p-21 activated kinase) signaling is defective in a mouse model of fragile X syndrome. J Neurosci. 2010;30:10977-84 pubmed publisher
immunocytochemistry; rat; 1:200	Borges V, Lee T, Christie D, Birch N. Neuroserpin regulates the density of dendritic protrusions and dendritic spine shape in cultured hippocampal neurons. J Neurosci Res. 2010;88:2610-7 pubmed publisher
immunohistochemistry; mouse	Zhang H, Sun S, Herreman A, De Strooper B, Bezprozvanny I. Role of presenilins in neuronal calcium homeostasis. J Neurosci. 2010;30:8566-80 pubmed publisher
western blot; mouse	Delint Ramirez I, FernÃ¡ndez E, BayÃ©s A, Kicsi E, Komiyama N, Grant S. In vivo composition of NMDA receptor signaling complexes differs between membrane subdomains and is modulated by PSD-95 and PSD-93. J Neurosci. 2010;30:8162-70 pubmed publisher
immunocytochemistry; African green monkey; 1:500	Siddiqui T, Pancaroglu R, Kang Y, Rooyakkers A, Craig A. LRRTMs and neuroligins bind neurexins with a differential code to cooperate in glutamate synapse development. J Neurosci. 2010;30:7495-506 pubmed publisher
immunocytochemistry; rat; 1:200	Oh J, Nam Y, Jo A, Cheon H, Rhee S, Park J, et al. Apolipoprotein E mRNA is transported to dendrites and may have a role in synaptic structural plasticity. J Neurochem. 2010;114:685-96 pubmed publisher
western blot; mouse	Uriu Y, Kiyonaka S, Miki T, Yagi M, Akiyama S, Mori E, et al. Rab3-interacting molecule gamma isoforms lacking the Rab3-binding domain induce long lasting currents but block neurotransmitter vesicle anchoring in voltage-dependent P/Q-type Ca2+ channels. J Biol Chem. 2010;285:21750-67 pubmed publisher
immunocytochemistry; mouse; 1:1000	Jenkins M, Christel C, Jiao Y, Abiria S, Kim K, Usachev Y, et al. Ca2+-dependent facilitation of Cav1.3 Ca2+ channels by densin and Ca2+/calmodulin-dependent protein kinase II. J Neurosci. 2010;30:5125-35 pubmed publisher
immunoprecipitation; rat; 1 ug/750 ul	Parkash J, d Anglemont de Tassigny X, Bellefontaine N, Campagne C, Mazure D, Buee Scherrer V, et al. Phosphorylation of N-methyl-D-aspartic acid receptor-associated neuronal nitric oxide synthase depends on estrogens and modulates hypothalamic nitric oxide production during the ovarian cycle. Endocrinology. 2010;151:2723-35 pubmed publisher
immunohistochemistry; rat; 1:1,000	Chen L, Rex C, Sanaiha Y, Lynch G, Gall C. Learning induces neurotrophin signaling at hippocampal synapses. Proc Natl Acad Sci U S A. 2010;107:7030-5 pubmed publisher
immunoprecipitation; mouse	Samudio Ruiz S, Allan A, Sheema S, Caldwell K. Hippocampal N-methyl-D-aspartate receptor subunit expression profiles in a mouse model of prenatal alcohol exposure. Alcohol Clin Exp Res. 2010;34:342-53 pubmed publisher
western blot; mouse; fig s2	Han M, Lin C, Meng S, Wang X. Proteomics analysis reveals overlapping functions of clustered protocadherins. Mol Cell Proteomics. 2010;9:71-83 pubmed publisher
immunohistochemistry; rat	Hozumi Y, Watanabe M, Otani K, Goto K. Diacylglycerol kinase beta promotes dendritic outgrowth and spine maturation in developing hippocampal neurons. BMC Neurosci. 2009;10:99 pubmed publisher
immunoprecipitation; rat; 1:2000	Yang G, Xiong W, Kojic L, Cynader M. Subunit-selective palmitoylation regulates the intracellular trafficking of AMPA receptor. Eur J Neurosci. 2009;30:35-46 pubmed publisher
immunohistochemistry; rat	Gainey M, Hurvitz Wolff J, Lambo M, Turrigiano G. Synaptic scaling requires the GluR2 subunit of the AMPA receptor. J Neurosci. 2009;29:6479-89 pubmed publisher
immunocytochemistry; rat; 1:500	Linhoff M, Lauren J, Cassidy R, Dobie F, Takahashi H, Nygaard H, et al. An unbiased expression screen for synaptogenic proteins identifies the LRRTM protein family as synaptic organizers. Neuron. 2009;61:734-49 pubmed publisher
western blot; rat; 1:5000	Xu X, Ye L, Ruan Q. Environmental enrichment induces synaptic structural modification after transient focal cerebral ischemia in rats. Exp Biol Med (Maywood). 2009;234:296-305 pubmed publisher
immunohistochemistry; human; 1:200	Jung J, Jung C, Choi H, Jun K, Yoo J, Kang S, et al. Diagnostic utility of expression of claudins in non-small cell lung cancer: different expression profiles in squamous cell carcinomas and adenocarcinomas. Pathol Res Pract. 2009;205:409-16 pubmed publisher
western blot; rat; 1:500	Soule J, Penke Z, Kanhema T, Alme M, Laroche S, Bramham C. Object-place recognition learning triggers rapid induction of plasticity-related immediate early genes and synaptic proteins in the rat dentate gyrus. Neural Plast. 2008;2008:269097 pubmed publisher
chromatin immunoprecipitation; rat	d Anglemont de Tassigny X, Campagne C, Steculorum S, Prevot V. Estradiol induces physical association of neuronal nitric oxide synthase with NMDA receptor and promotes nitric oxide formation via estrogen receptor activation in primary neuronal cultures. J Neurochem. 2009;109:214-24 pubmed publisher
immunohistochemistry; rat; 1:500	Peng Y, He S, Marie H, Zeng S, Ma J, Tan Z, et al. Coordinated changes in dendritic arborization and synaptic strength during neural circuit development. Neuron. 2009;61:71-84 pubmed publisher
immunohistochemistry; rat; 1:1,000	Lauterborn J, Pineda E, Chen L, Ramirez E, Lynch G, Gall C. Ampakines cause sustained increases in brain-derived neurotrophic factor signaling at excitatory synapses without changes in AMPA receptor subunit expression. Neuroscience. 2009;159:283-95 pubmed publisher
western blot; rat; 1:2000	Hozumi Y, Fukaya M, Adachi N, Saito N, Otani K, Kondo H, et al. Diacylglycerol kinase beta accumulates on the perisynaptic site of medium spiny neurons in the striatum. Eur J Neurosci. 2008;28:2409-22 pubmed publisher
immunocytochemistry; rat	McKellar C, Shatz C. Synaptogenesis in purified cortical subplate neurons. Cereb Cortex. 2009;19:1723-37 pubmed publisher
immunocytochemistry; rat	Lai K, Zhao Y, Ch ng T, Martin K. Importin-mediated retrograde transport of CREB2 from distal processes to the nucleus in neurons. Proc Natl Acad Sci U S A. 2008;105:17175-80 pubmed publisher
western blot; rat	Aoto J, Nam C, Poon M, Ting P, Chen L. Synaptic signaling by all-trans retinoic acid in homeostatic synaptic plasticity. Neuron. 2008;60:308-20 pubmed publisher
immunohistochemistry; human; 1:75	Leuba G, Savioz A, Vernay A, Carnal B, Kraftsik R, Tardif E, et al. Differential changes in synaptic proteins in the Alzheimer frontal cortex with marked increase in PSD-95 postsynaptic protein. J Alzheimers Dis. 2008;15:139-51 pubmed
western blot; mouse	Morice E, Andreae L, Cooke S, Vanes L, Fisher E, Tybulewicz V, et al. Preservation of long-term memory and synaptic plasticity despite short-term impairments in the Tc1 mouse model of Down syndrome. Learn Mem. 2008;15:492-500 pubmed publisher
immunohistochemistry; rat; 1:100	Henny P, Jones B. Projections from basal forebrain to prefrontal cortex comprise cholinergic, GABAergic and glutamatergic inputs to pyramidal cells or interneurons. Eur J Neurosci. 2008;27:654-70 pubmed publisher
western blot; human	Xu W, Schlüter O, Steiner P, Czervionke B, Sabatini B, Malenka R. Molecular dissociation of the role of PSD-95 in regulating synaptic strength and LTD. Neuron. 2008;57:248-62 pubmed publisher
immunocytochemistry; mouse; 1:200	Lacroix Fralish M, Tawfik V, Nutile McMenemy N, Harris B, DeLeo J. Differential regulation of neuregulin 1 expression by progesterone in astrocytes and neurons. Neuron Glia Biol. 2006;2:227-34 pubmed
western blot; mouse	Kioussi C, Appu M, LOHR C, Fischer K, Bajaj G, Leid M, et al. Co-expression of myosin II regulatory light chain and the NMDAR1 subunit in neonatal and adult mouse brain. Brain Res Bull. 2007;74:439-51 pubmed
immunocytochemistry; human; 1:200 western blot; human; 1:2,000	Aoto J, Ting P, Maghsoodi B, Xu N, Henkemeyer M, Chen L. Postsynaptic ephrinB3 promotes shaft glutamatergic synapse formation. J Neurosci. 2007;27:7508-19 pubmed
western blot; rat; 1:2000	Khurana R, Devaud L. Sex differences in neurotransmission parameters in response to repeated mild restraint stress exposures in intact male, female and ovariectomised female rats. J Neuroendocrinol. 2007;19:511-20 pubmed
western blot; rat	Egles C, Claudepierre T, Manglapus M, Champliaud M, Brunken W, Hunter D. Laminins containing the beta2 chain modulate the precise organization of CNS synapses. Mol Cell Neurosci. 2007;34:288-98 pubmed
western blot; rat	Krapivinsky G, Mochida S, Krapivinsky L, Cibulsky S, Clapham D. The TRPM7 ion channel functions in cholinergic synaptic vesicles and affects transmitter release. Neuron. 2006;52:485-96 pubmed
immunocytochemistry; rat; 1:500	Murphy J, Jensen O, Walikonis R. BRAG1, a Sec7 domain-containing protein, is a component of the postsynaptic density of excitatory synapses. Brain Res. 2006;1120:35-45 pubmed
immunohistochemistry - frozen section; rat immunohistochemistry; rat	Henny P, Jones B. Innervation of orexin/hypocretin neurons by GABAergic, glutamatergic or cholinergic basal forebrain terminals evidenced by immunostaining for presynaptic vesicular transporter and postsynaptic scaffolding proteins. J Comp Neurol. 2006;499:645-61 pubmed
western blot; human; 1:1000	Finardi A, Gardoni F, Bassanini S, Lasio G, Cossu M, Tassi L, et al. NMDA receptor composition differs among anatomically diverse malformations of cortical development. J Neuropathol Exp Neurol. 2006;65:883-93 pubmed
immunocytochemistry; mouse; 1:1000	Szabo Z, Obermair G, Cooper C, Zamponi G, Flucher B. Role of the synprint site in presynaptic targeting of the calcium channel CaV2.2 in hippocampal neurons. Eur J Neurosci. 2006;24:709-18 pubmed
western blot; rat	Schlüter O, Xu W, Malenka R. Alternative N-terminal domains of PSD-95 and SAP97 govern activity-dependent regulation of synaptic AMPA receptor function. Neuron. 2006;51:99-111 pubmed
immunocytochemistry; rat western blot; rat	Hosokawa T, Saito T, Asada A, Ohshima T, Itakura M, Takahashi M, et al. Enhanced activation of Ca2+/calmodulin-dependent protein kinase II upon downregulation of cyclin-dependent kinase 5-p35. J Neurosci Res. 2006;84:747-54 pubmed
immunocytochemistry; rat	Martin H, Henley J, Meyer G. Novel putative targets of N-ethylmaleimide sensitive fusion protein (NSF) and alpha/beta soluble NSF attachment proteins (SNAPs) include the Pak-binding nucleotide exchange factor betaPIX. J Cell Biochem. 2006;99:1203-15 pubmed
immunocytochemistry; mouse	Manzini M, Ward M, Zhang Q, Lieberman M, Mason C. The stop signal revised: immature cerebellar granule neurons in the external germinal layer arrest pontine mossy fiber growth. J Neurosci. 2006;26:6040-51 pubmed
western blot; mouse; 1:1000	Bouzioukh F, Daoudal G, Falk J, Debanne D, Rougon G, Castellani V. Semaphorin3A regulates synaptic function of differentiated hippocampal neurons. Eur J Neurosci. 2006;23:2247-54 pubmed
immunohistochemistry - frozen section; rat; 1:100 immunohistochemistry; rat; 1:100	Henny P, Jones B. Vesicular glutamate (VGlut), GABA (VGAT), and acetylcholine (VACht) transporters in basal forebrain axon terminals innervating the lateral hypothalamus. J Comp Neurol. 2006;496:453-67 pubmed
immunocytochemistry; mouse; 33 ug/ml	Bilousova T, Rusakov D, Ethell D, Ethell I. Matrix metalloproteinase-7 disrupts dendritic spines in hippocampal neurons through NMDA receptor activation. J Neurochem. 2006;97:44-56 pubmed
western blot; African green monkey; 1:2,000 western blot; rat; 1:2,000	Xie Z, Adamowicz W, Eldred W, Jakowski A, Kleiman R, Morton D, et al. Cellular and subcellular localization of PDE10A, a striatum-enriched phosphodiesterase. Neuroscience. 2006;139:597-607 pubmed
immunocytochemistry; rat; 1:500	Gerrow K, Romorini S, Nabi S, Colicos M, Sala C, El Husseini A. A preformed complex of postsynaptic proteins is involved in excitatory synapse development. Neuron. 2006;49:547-62 pubmed
immunocytochemistry; mouse; 33 ug/ml western blot; mouse; 33 ug/ml	Shi Y, Ethell I. Integrins control dendritic spine plasticity in hippocampal neurons through NMDA receptor and Ca2+/calmodulin-dependent protein kinase II-mediated actin reorganization. J Neurosci. 2006;26:1813-22 pubmed
immunohistochemistry; rat; 1:400	Nyffeler M, Zhang W, Feldon J, Knuesel I. Differential expression of PSD proteins in age-related spatial learning impairments. Neurobiol Aging. 2007;28:143-55 pubmed
immunocytochemistry; African green monkey	Sans N, Wang P, Du Q, Petralia R, Wang Y, Nakka S, et al. mPins modulates PSD-95 and SAP102 trafficking and influences NMDA receptor surface expression. Nat Cell Biol. 2005;7:1179-90 pubmed
western blot; mouse; 1:5000	Dietrich M, Mantese C, Porciuncula L, Ghisleni G, Vinade L, Souza D, et al. Exercise affects glutamate receptors in postsynaptic densities from cortical mice brain. Brain Res. 2005;1065:20-5 pubmed
immunocytochemistry; rat	Harms K, Craig A. Synapse composition and organization following chronic activity blockade in cultured hippocampal neurons. J Comp Neurol. 2005;490:72-84 pubmed
western blot; rat	Alele P, Devaud L. Differential adaptations in GABAergic and glutamatergic systems during ethanol withdrawal in male and female rats. Alcohol Clin Exp Res. 2005;29:1027-34 pubmed
immunocytochemistry; rat; 1:50	Cooper D, Saxena N, Yang H, Lee H, Moring A, Lee A, et al. Molecular and functional characterization of the electroneutral Na/HCO3 cotransporter NBCn1 in rat hippocampal neurons. J Biol Chem. 2005;280:17823-30 pubmed
immunohistochemistry; rat; 1:1000	Christopherson K, Ullian E, Stokes C, Mullowney C, Hell J, Agah A, et al. Thrombospondins are astrocyte-secreted proteins that promote CNS synaptogenesis. Cell. 2005;120:421-33 pubmed
western blot; mouse; 1:2000	Raiteri L, Stigliani S, Siri A, Passalacqua M, Melloni E, Raiteri M, et al. Glycine taken up through GLYT1 and GLYT2 heterotransporters into glutamatergic axon terminals of mouse spinal cord elicits release of glutamate by homotransporter reversal and through anion channels. Biochem Pharmacol. 2005;69:159-68 pubmed
	Du Z, Song Y, Chen X, Zhang W, Zhang G, Li H, et al. Knockdown of astrocytic Grin2a aggravates β-amyloid-induced memory and cognitive deficits through regulating nerve growth factor. Aging Cell. 2021;20:e13437 pubmed publisher
	Rigby M, Lawton A, Kaur G, Banduseela V, Kamm W, Lakkaraju A, et al. Endoplasmic reticulum acetyltransferases Atase1 and Atase2 differentially regulate reticulophagy, macroautophagy and cellular acetyl-CoA metabolism. Commun Biol. 2021;4:454 pubmed publisher
	Traetta M, Codagnone M, Uccelli N, Ramos A, Zárate S, Reinés A. Hippocampal neurons isolated from rats subjected to the valproic acid model mimic in vivo synaptic pattern: evidence of neuronal priming during early development in autism spectrum disorders. Mol Autism. 2021;12:23 pubmed publisher
	Pinto B, Morelli G, Rastogi M, Savardi A, Fumagalli A, Petretto A, et al. Rescuing Over-activated Microglia Restores Cognitive Performance in Juvenile Animals of the Dp(16) Mouse Model of Down Syndrome. Neuron. 2020;108:887-904.e12 pubmed publisher
	Takahashi M, Sugiyama A, Wei R, Kobayashi S, Fukuda K, Nishino H, et al. Hyperactive and impulsive behaviors of LMTK1 knockout mice. Sci Rep. 2020;10:15461 pubmed publisher
	Avchalumov Y, Trenet W, Piña Crespo J, MANDYAM C. SCH23390 Reduces Methamphetamine Self-Administration and Prevents Methamphetamine-Induced Striatal LTD. Int J Mol Sci. 2020;21: pubmed publisher
	Nguyen A, Sutley S, Koeppen J, Mina K, Woodruff S, Hanna S, et al. Astrocytic Ephrin-B1 Controls Excitatory-Inhibitory Balance in Developing Hippocampus. J Neurosci. 2020;40:6854-6871 pubmed publisher
	Martín Flores N, Pérez Sisqués L, Creus Muncunill J, Masana M, Gines S, Alberch J, et al. Synaptic RTP801 contributes to motor-learning dysfunction in Huntington's disease. Cell Death Dis. 2020;11:569 pubmed publisher
	Scheggi S, Guzzi F, Braccagni G, De Montis M, Parenti M, Gambarana C. Targeting PPARα in the rat valproic acid model of autism: focus on social motivational impairment and sex-related differences. Mol Autism. 2020;11:62 pubmed publisher
	Sun J, Liu Y, Zhu G, Cato C, Hao X, Qian L, et al. PKA and Ube3a regulate SK2 channel trafficking to promote synaptic plasticity in hippocampus: Implications for Angelman Syndrome. Sci Rep. 2020;10:9824 pubmed publisher
	Robert B, Moreau M, Dos Santos Carvalho S, Barthet G, Racca C, Bhouri M, et al. Vangl2 in the Dentate Network Modulates Pattern Separation and Pattern Completion. Cell Rep. 2020;31:107743 pubmed publisher
	Xu Z, Kim G, Tan J, Riso A, Sun Y, Xu E, et al. Elevated protein synthesis in microglia causes autism-like synaptic and behavioral aberrations. Nat Commun. 2020;11:1797 pubmed publisher
	Salesse C, Charest J, Doucet Beaupré H, Castonguay A, Labrecque S, De Koninck P, et al. Opposite Control of Excitatory and Inhibitory Synapse Formation by Slitrk2 and Slitrk5 on Dopamine Neurons Modulates Hyperactivity Behavior. Cell Rep. 2020;30:2374-2386.e5 pubmed publisher
	Testen A, Kim R, Reissner K. High-Resolution Three-Dimensional Imaging of Individual Astrocytes Using Confocal Microscopy. Curr Protoc Neurosci. 2020;91:e92 pubmed publisher
	Trovò L, Fuchs C, De Rosa R, Barbiero I, Tramarin M, Ciani E, et al. The green tea polyphenol epigallocatechin-3-gallate (EGCG) restores CDKL5-dependent synaptic defects in vitro and in vivo. Neurobiol Dis. 2020;138:104791 pubmed publisher
	Frega M, Selten M, Mossink B, Keller J, Linda K, Moerschen R, et al. Distinct Pathogenic Genes Causing Intellectual Disability and Autism Exhibit a Common Neuronal Network Hyperactivity Phenotype. Cell Rep. 2020;30:173-186.e6 pubmed publisher
	Lachance V, Wang Q, Sweet E, Choi I, Cai C, Zhuang X, et al. Autophagy protein NRBF2 has reduced expression in Alzheimer's brains and modulates memory and amyloid-beta homeostasis in mice. Mol Neurodegener. 2019;14:43 pubmed publisher
	Frega M, Linda K, Keller J, Gümüş Akay G, Mossink B, Van Rhijn J, et al. Neuronal network dysfunction in a model for Kleefstra syndrome mediated by enhanced NMDAR signaling. Nat Commun. 2019;10:4928 pubmed publisher
	Nishino H, Saito T, Wei R, Takano T, Tsutsumi K, Taniguchi M, et al. The LMTK1-TBC1D9B-Rab11A Cascade Regulates Dendritic Spine Formation via Endosome Trafficking. J Neurosci. 2019;39:9491-9502 pubmed publisher
	Chen R, Lyu Z, Xie D, Huang D, Chen Y, Wu C. Long-Term Potentiation of Prelimbic Cortex Ascribed to Heat-Sensitization Responses of Moxibustion. Evid Based Complement Alternat Med. 2019;2019:9465181 pubmed publisher
	Xu Z, Tan J, Xu H, Hill C, Ostrovskaya O, Martemyanov K, et al. Caspase-2 promotes AMPA receptor internalization and cognitive flexibility via mTORC2-AKT-GSK3β signaling. Nat Commun. 2019;10:3622 pubmed publisher
	Laird J, Gardner S, Kopel A, Kerov V, Lee A, Baker S. Rescue of Rod Synapses by Induction of Cav Alpha 1F in the Mature Cav1.4 Knock-Out Mouse Retina. Invest Ophthalmol Vis Sci. 2019;60:3150-3161 pubmed publisher
	Sanchez Arias J, Liu M, Choi C, Ebert S, Brown C, Swayne L. Pannexin 1 Regulates Network Ensembles and Dendritic Spine Development in Cortical Neurons. Eneuro. 2019;6: pubmed publisher
	Vezzoli E, Caron I, Talpo F, Besusso D, Conforti P, Battaglia E, et al. Inhibiting pathologically active ADAM10 rescues synaptic and cognitive decline in Huntington's disease. J Clin Invest. 2019;130:2390-2403 pubmed publisher
	Roby D, Ruiz F, Kermath B, Voorhees J, Niehoff M, Zhang J, et al. Pharmacological activation of the nuclear receptor REV-ERB reverses cognitive deficits and reduces amyloid-β burden in a mouse model of Alzheimer's disease. PLoS ONE. 2019;14:e0215004 pubmed publisher
	Edfawy M, Guedes J, Pereira M, Laranjo M, Carvalho M, Gao X, et al. Abnormal mGluR-mediated synaptic plasticity and autism-like behaviours in Gprasp2 mutant mice. Nat Commun. 2019;10:1431 pubmed publisher
	Huang G, Chen S, Chen X, Zheng J, Xu Z, Doostparast Torshizi A, et al. Uncovering the Functional Link Between SHANK3 Deletions and Deficiency in Neurodevelopment Using iPSC-Derived Human Neurons. Front Neuroanat. 2019;13:23 pubmed publisher
	Li J, Chiu J, Pratico D. Full recovery of the Alzheimer's disease phenotype by gain of function of vacuolar protein sorting 35. Mol Psychiatry. 2019;: pubmed publisher
	Geisler S, Schöpf C, Stanika R, Kalb M, Campiglio M, Repetto D, et al. Presynaptic α2δ-2 Calcium Channel Subunits Regulate Postsynaptic GABAA Receptor Abundance and Axonal Wiring. J Neurosci. 2019;39:2581-2605 pubmed publisher
	Yu J, Moutal A, Dorame A, Bellampalli S, Chefdeville A, Kanazawa I, et al. Phosphorylated CRMP2 Regulates Spinal Nociceptive Neurotransmission. Mol Neurobiol. 2018;: pubmed publisher
	Swarnkar S, Avchalumov Y, Raveendra B, Grinman E, Puthanveettil S. Kinesin Family of Proteins Kif11 and Kif21B Act as Inhibitory Constraints of Excitatory Synaptic Transmission Through Distinct Mechanisms. Sci Rep. 2018;8:17419 pubmed publisher
	Itoh M, Yamashita M, Kaneko M, Okuno H, Abe M, Yamazaki M, et al. Deficiency of AMPAR-Palmitoylation Aggravates Seizure Susceptibility. J Neurosci. 2018;38:10220-10235 pubmed publisher
	Blanco Suarez E, Liu T, Kopelevich A, Allen N. Astrocyte-Secreted Chordin-like 1 Drives Synapse Maturation and Limits Plasticity by Increasing Synaptic GluA2 AMPA Receptors. Neuron. 2018;100:1116-1132.e13 pubmed publisher
	Thomas R, Gibon J, Chen C, Chierzi S, Soubannier V, Baulac S, et al. The Nogo Receptor Ligand LGI1 Regulates Synapse Number and Synaptic Activity in Hippocampal and Cortical Neurons. Eneuro. 2018;5: pubmed publisher
	Wang W, Le A, Hou B, Lauterborn J, Cox C, Levin E, et al. Memory-Related Synaptic Plasticity Is Sexually Dimorphic in Rodent Hippocampus. J Neurosci. 2018;38:7935-7951 pubmed publisher
	Cataldi S, Follett J, Fox J, Tatarnikov I, Kadgien C, Gustavsson E, et al. Altered dopamine release and monoamine transporters in Vps35 p.D620N knock-in mice. NPJ Parkinsons Dis. 2018;4:27 pubmed publisher
	Oh J, Lim C, Yoo K, Park H, Park Y, Kim E, et al. Adenomatous polyposis coli-stimulated GEF 1 (Asef1) is a negative regulator of excitatory synaptic function. J Neurochem. 2018;147:595-608 pubmed publisher
	Zhang P, Lu H, Peixoto R, Pines M, Ge Y, Oku S, et al. Heparan Sulfate Organizes Neuronal Synapses through Neurexin Partnerships. Cell. 2018;174:1450-1464.e23 pubmed publisher
	Risher W, Kim N, Koh S, Choi J, Mitev P, Spence E, et al. Thrombospondin receptor α2δ-1 promotes synaptogenesis and spinogenesis via postsynaptic Rac1. J Cell Biol. 2018;217:3747-3765 pubmed publisher
	Sun J, Liu Y, Jia Y, Hao X, Lin W, Tran J, et al. UBE3A-mediated p18/LAMTOR1 ubiquitination and degradation regulate mTORC1 activity and synaptic plasticity. elife. 2018;7: pubmed publisher
	Koeppen J, Nguyen A, Nikolakopoulou A, Garcia M, Hanna S, Woodruff S, et al. Functional Consequences of Synapse Remodeling Following Astrocyte-Specific Regulation of Ephrin-B1 in the Adult Hippocampus. J Neurosci. 2018;38:5710-5726 pubmed publisher
	di Meco A, Li J, Barrero C, Merali S, Pratico D. Elevated levels of brain homocysteine directly modulate the pathological phenotype of a mouse model of tauopathy. Mol Psychiatry. 2018;: pubmed publisher
	Tramarin M, Rusconi L, Pizzamiglio L, Barbiero I, Peroni D, Scaramuzza L, et al. The antidepressant tianeptine reverts synaptic AMPA receptor defects caused by deficiency of CDKL5. Hum Mol Genet. 2018;27:2052-2063 pubmed publisher
	Fujita K, Chen X, Homma H, Tagawa K, Amano M, Saito A, et al. Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology. Nat Commun. 2018;9:433 pubmed publisher
	Repar N, Li H, Aguilar J, Li Q, Drobne D, Hong Y. Silver nanoparticles induce neurotoxicity in a human embryonic stem cell-derived neuron and astrocyte network. Nanotoxicology. 2018;12:104-116 pubmed publisher
	Lauretti E, Pratico D. Effect of canola oil consumption on memory, synapse and neuropathology in the triple transgenic mouse model of Alzheimer's disease. Sci Rep. 2017;7:17134 pubmed publisher
	Deshpande A, Yadav S, Dao D, Wu Z, Hokanson K, Cahill M, et al. Cellular Phenotypes in Human iPSC-Derived Neurons from a Genetic Model of Autism Spectrum Disorder. Cell Rep. 2017;21:2678-2687 pubmed publisher
	Cox C, Palmer L, Pham D, Trieu B, Gall C, Lynch G. Experiential learning in rodents: past experience enables rapid learning and localized encoding in hippocampus. Learn Mem. 2017;24:569-579 pubmed publisher
	Farhy Tselnicker I, van Casteren A, Lee A, Chang V, Aricescu A, Allen N. Astrocyte-Secreted Glypican 4 Regulates Release of Neuronal Pentraxin 1 from Axons to Induce Functional Synapse Formation. Neuron. 2017;96:428-445.e13 pubmed publisher
	Krishnan M, Van Steenwinckel J, Schang A, Yan J, Arnadottir J, Le Charpentier T, et al. Integrative genomics of microglia implicates DLG4 (PSD95) in the white matter development of preterm infants. Nat Commun. 2017;8:428 pubmed publisher
	Briz V, Restivo L, Pasciuto E, Juczewski K, Mercaldo V, Lo A, et al. The non-coding RNA BC1 regulates experience-dependent structural plasticity and learning. Nat Commun. 2017;8:293 pubmed publisher
	Lauretti E, Iuliano L, Pratico D. Extra-virgin olive oil ameliorates cognition and neuropathology of the 3xTg mice: role of autophagy. Ann Clin Transl Neurol. 2017;4:564-574 pubmed publisher
	Lei W, Myers K, Rui Y, Hladyshau S, Tsygankov D, Zheng J. Phosphoinositide-dependent enrichment of actin monomers in dendritic spines regulates synapse development and plasticity. J Cell Biol. 2017;216:2551-2564 pubmed publisher
	Dante S, Petrelli A, Petrini E, Marotta R, Maccione A, Alabastri A, et al. Selective Targeting of Neurons with Inorganic Nanoparticles: Revealing the Crucial Role of Nanoparticle Surface Charge. ACS Nano. 2017;11:6630-6640 pubmed publisher
	Von Stetina S, Liang J, Marnellos G, Mango S. Temporal regulation of epithelium formation mediated by FoxA, MKLP1, MgcRacGAP, and PAR-6. Mol Biol Cell. 2017;28:2042-2065 pubmed publisher
	Zhang L, Wang L, Hiremath U, Bisoyi H, Nair G, Yelamaggad C, et al. Dynamic Orthogonal Switching of a Thermoresponsive Self-Organized Helical Superstructure. Adv Mater. 2017;29: pubmed publisher
	Li J, Barrero C, Merali S, Pratico D. Genetic absence of ALOX5 protects from homocysteine-induced memory impairment, tau phosphorylation and synaptic pathology. Hum Mol Genet. 2017;26:1855-1862 pubmed publisher
	Hozumi Y, Fujiwara H, Kaneko K, Fujii S, Topham M, Watanabe M, et al. Diacylglycerol kinase Îµ localizes to subsurface cisterns of cerebellar Purkinje cells. Cell Tissue Res. 2017;368:441-458 pubmed publisher
	Mi Z, Si T, Kapadia K, Li Q, Muma N. Receptor-stimulated transamidation induces activation of Rac1 and Cdc42 and the regulation of dendritic spines. Neuropharmacology. 2017;117:93-105 pubmed publisher
	Thakar S, Wang L, Yu T, Ye M, Onishi K, Scott J, et al. Evidence for opposing roles of Celsr3 and Vangl2 in glutamatergic synapse formation. Proc Natl Acad Sci U S A. 2017;114:E610-E618 pubmed publisher
	Früh S, Romanos J, Panzanelli P, Bürgisser D, Tyagarajan S, Campbell K, et al. Neuronal Dystroglycan Is Necessary for Formation and Maintenance of Functional CCK-Positive Basket Cell Terminals on Pyramidal Cells. J Neurosci. 2016;36:10296-10313 pubmed
	Matikainen Ankney B, Kezunovic N, Mesias R, Tian Y, Williams F, Huntley G, et al. Altered Development of Synapse Structure and Function in Striatum Caused by Parkinson's Disease-Linked LRRK2-G2019S Mutation. J Neurosci. 2016;36:7128-41 pubmed publisher
	Sun J, Liu Y, Tran J, O Neal P, Baudry M, Bi X. mTORC1-S6K1 inhibition or mTORC2 activation improves hippocampal synaptic plasticity and learning in Angelman syndrome mice. Cell Mol Life Sci. 2016;73:4303-4314 pubmed
	Burguete A, Almeida S, Gao F, Kalb R, Akins M, Bonini N. GGGGCC microsatellite RNA is neuritically localized, induces branching defects, and perturbs transport granule function. elife. 2015;4:e08881 pubmed publisher
	Begum A, Guoynes C, Cho J, Hao J, Lutfy K, Hong Y. Rapid generation of sub-type, region-specific neurons and neural networks from human pluripotent stem cell-derived neurospheres. Stem Cell Res. 2015;15:731-741 pubmed publisher
	Sun J, Zhu G, Liu Y, Standley S, Ji A, Tunuguntla R, et al. UBE3A Regulates Synaptic Plasticity and Learning and Memory by Controlling SK2 Channel Endocytosis. Cell Rep. 2015;12:449-61 pubmed publisher
	Aoto J, FÃ¶ldy C, Ilcus S, Tabuchi K, SÃ¼dhof T. Distinct circuit-dependent functions of presynaptic neurexin-3 at GABAergic and glutamatergic synapses. Nat Neurosci. 2015;18:997-1007 pubmed publisher
	Law R, Dixon Salazar T, Jerber J, Cai N, Abbasi A, Zaki M, et al. Biallelic truncating mutations in FMN2, encoding the actin-regulatory protein Formin 2, cause nonsyndromic autosomal-recessive intellectual disability. Am J Hum Genet. 2014;95:721-8 pubmed publisher
	Seese R, Wang K, Yao Y, Lynch G, Gall C. Spaced training rescues memory and ERK1/2 signaling in fragile X syndrome model mice. Proc Natl Acad Sci U S A. 2014;111:16907-12 pubmed publisher
	Tomioka N, Yasuda H, Miyamoto H, Hatayama M, Morimura N, Matsumoto Y, et al. Elfn1 recruits presynaptic mGluR7 in trans and its loss results in seizures. Nat Commun. 2014;5:4501 pubmed publisher
	Ozkan E, Creson T, Kramar E, Rojas C, Seese R, Babyan A, et al. Reduced cognition in Syngap1 mutants is caused by isolated damage within developing forebrain excitatory neurons. Neuron. 2014;82:1317-33 pubmed publisher
	Keeley P, Luna G, Fariss R, Skyles K, Madsen N, Raven M, et al. Development and plasticity of outer retinal circuitry following genetic removal of horizontal cells. J Neurosci. 2013;33:17847-62 pubmed publisher
	Kim T, Vidal G, Djurisic M, William C, Birnbaum M, Garcia K, et al. Human LilrB2 is a ?-amyloid receptor and its murine homolog PirB regulates synaptic plasticity in an Alzheimer's model. Science. 2013;341:1399-404 pubmed publisher
	Seese R, Chen L, Cox C, Schulz D, Babayan A, Bunney W, et al. Synaptic abnormalities in the infralimbic cortex of a model of congenital depression. J Neurosci. 2013;33:13441-8 pubmed publisher
	Orlando C, Ster J, Gerber U, Fawcett J, Raineteau O. Perisynaptic chondroitin sulfate proteoglycans restrict structural plasticity in an integrin-dependent manner. J Neurosci. 2012;32:18009-17, 18017a pubmed publisher
	Fan J, Cowan C, Zhang L, Hayden M, Raymond L. Interaction of postsynaptic density protein-95 with NMDA receptors influences excitotoxicity in the yeast artificial chromosome mouse model of Huntington's disease. J Neurosci. 2009;29:10928-38 pubmed publisher
	Wang X, Bozdagi O, Nikitczuk J, Zhai Z, Zhou Q, Huntley G. Extracellular proteolysis by matrix metalloproteinase-9 drives dendritic spine enlargement and long-term potentiation coordinately. Proc Natl Acad Sci U S A. 2008;105:19520-5 pubmed publisher
	Fogel A, Akins M, Krupp A, Stagi M, Stein V, Biederer T. SynCAMs organize synapses through heterophilic adhesion. J Neurosci. 2007;27:12516-30 pubmed
	Fedulov V, Rex C, Simmons D, Palmer L, Gall C, Lynch G. Evidence that long-term potentiation occurs within individual hippocampal synapses during learning. J Neurosci. 2007;27:8031-9 pubmed
	Alvarez V, Ridenour D, Sabatini B. Distinct structural and ionotropic roles of NMDA receptors in controlling spine and synapse stability. J Neurosci. 2007;27:7365-76 pubmed
	d Anglemont de Tassigny X, Campagne C, Dehouck B, Leroy D, Holstein G, Beauvillain J, et al. Coupling of neuronal nitric oxide synthase to NMDA receptors via postsynaptic density-95 depends on estrogen and contributes to the central control of adult female reproduction. J Neurosci. 2007;27:6103-14 pubmed
	Chen L, Rex C, Casale M, Gall C, Lynch G. Changes in synaptic morphology accompany actin signaling during LTP. J Neurosci. 2007;27:5363-72 pubmed
	Goddard C, Butts D, Shatz C. Regulation of CNS synapses by neuronal MHC class I. Proc Natl Acad Sci U S A. 2007;104:6828-33 pubmed
	Thies E, Mandelkow E. Missorting of tau in neurons causes degeneration of synapses that can be rescued by the kinase MARK2/Par-1. J Neurosci. 2007;27:2896-907 pubmed
	Lacor P, Buniel M, Furlow P, Clemente A, Velasco P, Wood M, et al. Abeta oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease. J Neurosci. 2007;27:796-807 pubmed
	Das S, Banker G. The role of protein interaction motifs in regulating the polarity and clustering of the metabotropic glutamate receptor mGluR1a. J Neurosci. 2006;26:8115-25 pubmed
	Gorski J, Gomez L, Scott J, Dell Acqua M. Association of an A-kinase-anchoring protein signaling scaffold with cadherin adhesion molecules in neurons and epithelial cells. Mol Biol Cell. 2005;16:3574-90 pubmed
	Zhang H, Webb D, Asmussen H, Niu S, Horwitz A. A GIT1/PIX/Rac/PAK signaling module regulates spine morphogenesis and synapse formation through MLC. J Neurosci. 2005;25:3379-88 pubmed
	Hori K, Yasuda H, Konno D, Maruoka H, Tsumoto T, Sobue K. NMDA receptor-dependent synaptic translocation of insulin receptor substrate p53 via protein kinase C signaling. J Neurosci. 2005;25:2670-81 pubmed
	Schlief M, Craig A, Gitlin J. NMDA receptor activation mediates copper homeostasis in hippocampal neurons. J Neurosci. 2005;25:239-46 pubmed
	Weiner J, Wang X, Tapia J, Sanes J. Gamma protocadherins are required for synaptic development in the spinal cord. Proc Natl Acad Sci U S A. 2005;102:8-14 pubmed
	Lacor P, Buniel M, Chang L, Fernandez S, Gong Y, Viola K, et al. Synaptic targeting by Alzheimer's-related amyloid beta oligomers. J Neurosci. 2004;24:10191-200 pubmed
	Israely I, Costa R, Xie C, Silva A, Kosik K, Liu X. Deletion of the neuron-specific protein delta-catenin leads to severe cognitive and synaptic dysfunction. Curr Biol. 2004;14:1657-63 pubmed
	Kang R, Swayze R, Lise M, Gerrow K, Mullard A, Honer W, et al. Presynaptic trafficking of synaptotagmin I is regulated by protein palmitoylation. J Biol Chem. 2004;279:50524-36 pubmed
	Ossipow V, Pellissier F, Schaad O, Ballivet M. Gene expression analysis of the critical period in the visual cortex. Mol Cell Neurosci. 2004;27:70-83 pubmed
	Schratt G, Nigh E, Chen W, Hu L, Greenberg M. BDNF regulates the translation of a select group of mRNAs by a mammalian target of rapamycin-phosphatidylinositol 3-kinase-dependent pathway during neuronal development. J Neurosci. 2004;24:7366-77 pubmed
	Gitler D, Xu Y, Kao H, Lin D, Lim S, Feng J, et al. Molecular determinants of synapsin targeting to presynaptic terminals. J Neurosci. 2004;24:3711-20 pubmed
	Parker M, Zhao S, Bredt D, Sanes J, Feng G. PSD93 regulates synaptic stability at neuronal cholinergic synapses. J Neurosci. 2004;24:378-88 pubmed
	Henkemeyer M, Itkis O, Ngo M, Hickmott P, Ethell I. Multiple EphB receptor tyrosine kinases shape dendritic spines in the hippocampus. J Cell Biol. 2003;163:1313-26 pubmed
	Colledge M, Snyder E, Crozier R, Soderling J, Jin Y, Langeberg L, et al. Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expression. Neuron. 2003;40:595-607 pubmed
	Gardoni F, Pagliardini S, Setola V, Bassanini S, Cattabeni F, Battaglia G, et al. The NMDA receptor complex is altered in an animal model of human cerebral heterotopia. J Neuropathol Exp Neurol. 2003;62:662-75 pubmed
	Zhang H, Webb D, Asmussen H, Horwitz A. Synapse formation is regulated by the signaling adaptor GIT1. J Cell Biol. 2003;161:131-42 pubmed
	Obermair G, Kaufmann W, Knaus H, Flucher B. The small conductance Ca2+-activated K+ channel SK3 is localized in nerve terminals of excitatory synapses of cultured mouse hippocampal neurons. Eur J Neurosci. 2003;17:721-31 pubmed
	Konno D, Ko J, Usui S, Hori K, Maruoka H, Inui M, et al. The postsynaptic density and dendritic raft localization of PSD-Zip70, which contains an N-myristoylation sequence and leucine-zipper motifs. J Cell Sci. 2002;115:4695-706 pubmed
	Fong D, Rao A, Crump F, Craig A. Rapid synaptic remodeling by protein kinase C: reciprocal translocation of NMDA receptors and calcium/calmodulin-dependent kinase II. J Neurosci. 2002;22:2153-64 pubmed
	Rao A, Cha E, Craig A. Mismatched appositions of presynaptic and postsynaptic components in isolated hippocampal neurons. J Neurosci. 2000;20:8344-53 pubmed
	Ethell I, Hagihara K, Miura Y, Irie F, Yamaguchi Y. Synbindin, A novel syndecan-2-binding protein in neuronal dendritic spines. J Cell Biol. 2000;151:53-68 pubmed
	Allison D, Chervin A, Gelfand V, Craig A. Postsynaptic scaffolds of excitatory and inhibitory synapses in hippocampal neurons: maintenance of core components independent of actin filaments and microtubules. J Neurosci. 2000;20:4545-54 pubmed
	Naisbitt S, Valtschanoff J, Allison D, Sala C, Kim E, Craig A, et al. Interaction of the postsynaptic density-95/guanylate kinase domain-associated protein complex with a light chain of myosin-V and dynein. J Neurosci. 2000;20:4524-34 pubmed
	Sans N, Petralia R, Wang Y, Blahos J, Hell J, Wenthold R. A developmental change in NMDA receptor-associated proteins at hippocampal synapses. J Neurosci. 2000;20:1260-71 pubmed
	Christopherson K, Hillier B, Lim W, Bredt D. PSD-95 assembles a ternary complex with the N-methyl-D-aspartic acid receptor and a bivalent neuronal NO synthase PDZ domain. J Biol Chem. 1999;274:27467-73 pubmed
	Ethell I, Yamaguchi Y. Cell surface heparan sulfate proteoglycan syndecan-2 induces the maturation of dendritic spines in rat hippocampal neurons. J Cell Biol. 1999;144:575-86 pubmed
	Torres R, Firestein B, Dong H, Staudinger J, Olson E, Huganir R, et al. PDZ proteins bind, cluster, and synaptically colocalize with Eph receptors and their ephrin ligands. Neuron. 1998;21:1453-63 pubmed
	Zhang W, Vazquez L, Apperson M, Kennedy M. Citron binds to PSD-95 at glutamatergic synapses on inhibitory neurons in the hippocampus. J Neurosci. 1999;19:96-108 pubmed
	Koulen P, Fletcher E, Craven S, Bredt D, Wassle H. Immunocytochemical localization of the postsynaptic density protein PSD-95 in the mammalian retina. J Neurosci. 1998;18:10136-49 pubmed
	Kornau H, Schenker L, Kennedy M, Seeburg P. Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95. Science. 1995;269:1737-40 pubmed
	Cho K, Hunt C, Kennedy M. The rat brain postsynaptic density fraction contains a homolog of the Drosophila discs-large tumor suppressor protein. Neuron. 1992;9:929-42 pubmed
	Nyman C, Boman J, GidlÃ¶f A. Von Garrelts' uroflowmeter. A technical evaluation. Urol Int. 1979;34:184-9 pubmed

image

image 1 :

Immunofluorescent analysis of PSD95 using PSD95 Monoclonal antibody (6G6-1C9) (Product# MA1-045) shows staining in HeLa cells. PSD95 staining (green), F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with or an antibody recognizing PSD95 (Product# MA1-045) at a dilution of 1:100-1:200 over night at 4 ?C, washed with PBS and incubated with a DyLight-488 conjugated secondary antibody (Product# 35552 for GAR, Product# 35503 for GAM). Images were taken at 60X magnification.

image 2 :

Immunofluorescent analysis of PSD95 using PSD95 Monoclonal antibody (6G6-1C9) (Product# MA1-045) shows staining in U251 glioma cells. PSD95 staining (green), F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with or an antibody recognizing PSD95 (Product# MA1-045) at a dilution of 1:100-1:200 over night at 4 ?C, washed with PBS and incubated with a DyLight-488 conjugated secondary antibody (Product# 35552 for GAR, Product# 35503 for GAM). Images were taken at 60X magnification.

image 3 :

Immunofluorescent analysis of PSD95 using PSD95 Monoclonal antibody (6G6-1C9) (Product# MA1-045) shows staining in C6 glioma cells. PSD95 staining (green), F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with or an antibody recognizing PSD95 (Product# MA1-045) at a dilution of 1:100-1:200 over night at 4 ?C, washed with PBS and incubated with a DyLight-488 conjugated secondary antibody (Product# 35552 for GAR, Product# 35503 for GAM). Images were taken at 60X magnification.

product information

Product Type :

Antibody

Product Name :

PSD-95 Monoclonal Antibody (6G6-1C9)

Catalog # :

MA1-045

Quantity :

100 µL

Price :

US 449.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

Flow Cytometry: 2 µg/test, Immunocytochemistry: 1:500, Immunoprecipitation: Assay-dependent, Western Blot: 1:2,000

Species :

Human, Mouse, Rat

Clone :

6G6-1C9

Isotype :

IgG2a

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

Post Synaptic Density 95 kDa (PSD-95), also known as synapse associated protein 90 kDa (SAP90), is one of a family of membrane-associated proteins found in the postsynaptic density in forebrain neurons and certain presynaptic structures in the cerebellum. Like other members of the family, PSD-95 has three 90 amino acid repeats called PDZ domains followed by an SH3 domain and a yeast guanylate kinase homology (GuK) domain. PSD-95 is believed to participate in the clustering of certain proteins, including NMDA receptors, Shaker-type potassium channels at the synaptic membrane in central nervous system (CNS) neurons. There are two principal modes of interaction between PSD-95 and other proteins. NMDA receptors and shaker-type potassium channels both share C-terminal sequence homology consisting of a threonine/serine-X-valine-COOH (T/SXV) motif. Other neuronal proteins that share this motif (beta 1 adrenergic receptor, some serotonin receptors, some sodium channel subunits, and additional potassium channel subunits), and some of these proteins may interact with PSD-95 by binding to its PDZ domains. Neuronal nitric oxide synthase (nNOS), which lacks the T/SXV motif but which has its own PDZ domain, has been shown to associate with PSD-95 in vitro through a pseudo-homotypic PDZ-PDZ interaction.

Immunogen :

Purified recombinant rat PSD-95.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 2 µg/test, Immunocytochemistry: 1:500, Immunoprecipitation: Assay-dependent, Western Blot: 1:2,000

Aliases :

discs large homolog 4; discs large MAGUK scaffold protein 4; discs, large homolog 4; discs, large homolog 4 (Drosophila); disks large homolog 4; Dlg4; Dlgh4; FLJ97752; FLJ98574; post synaptic density; postsynaptic density protein 95; post-synaptic density protein 95; PSD95; PSD-95; PSD-95 alpha 2b; PSD-95 beta; Sap90; SAP-90; SAP90A; Synapse-associated protein 90; synapse-associated protein SAP90; Tax interaction protein 15

more info or order :

Invitrogen product webpage