This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
SSEA1 Monoclonal Antibody (MC-480), DyLight 650
catalog :
MA1-022-D650
quantity :
100 uL
price :
US 451.00
clonality :
monoclonal
host :
mouse
conjugate :
DyLight 650
reactivity :
human, mouse
application :
immunocytochemistry, flow cytometry
citations: 3
Reference
Qin W, Ugur E, Mulholland C, Bultmann S, Solovei I, Modic M, et al. Phosphorylation of the HP1β hinge region sequesters KAP1 in heterochromatin and promotes the exit from naïve pluripotency. Nucleic Acids Res. 2021;49:7406-7423 pubmed publisher
Piprek R, Kolasa M, Podkowa D, Kloc M, Kubiak J. N-Cadherin Is Critical for the Survival of Germ Cells, the Formation of Steroidogenic Cells, and the Architecture of Developing Mouse Gonads. Cells. 2019;8: pubmed publisher
Piprek R, Kolasa M, Podkowa D, Kloc M, Kubiak J. Tissue-specific knockout of E-cadherin (Cdh1) in developing mouse gonads causes germ cells loss. Reproduction. 2019;158:147-157 pubmed publisher
product information
Product Type :
Antibody
Product Name :
SSEA1 Monoclonal Antibody (MC-480), DyLight 650
Catalog # :
MA1-022-D650
Quantity :
100 uL
Price :
US 451.00
Clonality :
Monoclonal
Purity :
Affinity chromatography - MBP
Host :
Mouse
Reactivity :
Human, Mouse
Applications :
Flow Cytometry: 1:50-1:500, Immunocytochemistry: 1:10-1:100
Species :
Human, Mouse
Clone :
MC-480
Isotype :
IgM
Storage :
4 C, do not freeze
Description :
CD15 (Lewis X, Le(x); stage specific embryonic antigen-1, SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin's disease.
Immunogen :
BALB/c mouse immunized with F9 teratocarcinoma stem cells (X-irradiated).
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:50-1:500, Immunocytochemistry: 1:10-1:100
Aliases :
FUTIV; Lewis X; SSEA-1
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA