SSEA4 Monoclonal Antibody (MC-813-70) | Invitrogen MA1-021 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SSEA4 Monoclonal Antibody (MC-813-70)

catalog :

MA1-021

quantity :

100 ug

price :

US 399.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MC-813-70

application :

immunocytochemistry, flow cytometry, other

citations: 24

Reference
Li H, Bartke R, Zhao L, Verma Y, Horacek A, Rechav Ben Natan A, et al. Functional annotation of variants of the BRCA2 gene via locally haploid human pluripotent stem cells. Nat Biomed Eng. 2023;: pubmed publisher
Li H, Busquets O, Verma Y, Syed K, Kutnowski N, Pangilinan G, et al. Highly efficient generation of isogenic pluripotent stem cell models using prime editing. elife. 2022;11: pubmed publisher
Stutzman M, Kim C, Tester D, Hamrick S, Dotzler S, Giudicessi J, et al. Characterization of N-terminal RYR2 variants outside CPVT1 hotspot regions using patient iPSCs reveal pathogenesis and therapeutic potential. Stem Cell Reports. 2022;17:2023-2036 pubmed publisher
Hamrick S, Kim C, Tester D, Giudicessi J, Ackerman M. A Patient-Specific Re-Engineered Cardiomyocyte Model Confirms the Circumstance-Dependent Arrhythmia Risk Associated with the African-Specific Common SCN5A Polymorphism (p.S1103Y): Implications for the Increased Sudden Deaths Observed in Black Individ. Heart Rhythm. 2021;: pubmed publisher
Ziegler G, Radtke F, Vitale M, Preu xdf e A, Klopocki E, Herms S, et al. Generation of multiple human iPSC lines from peripheral blood mononuclear cells of two SLC2A3 deletion and two SLC2A3 duplication carriers. Stem Cell Res. 2021;56:102526 pubmed publisher
Ajiro M, Awaya T, Kim Y, Iida K, Denawa M, Tanaka N, et al. Therapeutic manipulation of IKBKAP mis-splicing with a small molecule to cure familial dysautonomia. Nat Commun. 2021;12:4507 pubmed publisher
Cousin M, Creighton B, Breau K, Spillmann R, Torti E, Dontu S, et al. Pathogenic SPTBN1 variants cause an autosomal dominant neurodevelopmental syndrome. Nat Genet. 2021;53:1006-1021 pubmed publisher
Kimura K, Koizumi T, Urasawa T, Ohta Y, Takakura D, Kawasaki N. Glycoproteomic analysis of the changes in protein N-glycosylation during neuronal differentiation in human-induced pluripotent stem cells and derived neuronal cells. Sci Rep. 2021;11:11169 pubmed publisher
Niceforo A, Marioli C, Colasuonno F, Petrini S, Massey K, Tartaglia M, et al. Altered cytoskeletal arrangement in induced pluripotent stem cells (iPSCs) and motor neurons from patients with riboflavin transporter deficiency. Dis Model Mech. 2021;: pubmed publisher
Sridharan D, Palaniappan A, Blackstone B, Dougherty J, Kumar N, Seshagiri P, et al. In situ differentiation of human-induced pluripotent stem cells into functional cardiomyocytes on a coaxial PCL-gelatin nanofibrous scaffold. Mater Sci Eng C Mater Biol Appl. 2021;118:111354 pubmed publisher
Molina S, Beltran A, Beltran A. Generation of an integration-free induced pluripotent stem cell line (UNC001-A) from blood of a healthy individual. Stem Cell Res. 2020;49:102015 pubmed publisher
Bradley J, Wang J, Pacey S, Warren A, Pober J, Al Lamki R. Tumor necrosis factor receptor-2 signaling pathways promote survival of cancer stem-like CD133+ cells in clear cell renal carcinoma. FASEB Bioadv. 2020;2:126-144 pubmed publisher
Vosough M, Ravaioli F, Zabulica M, Capri M, Garagnani P, Franceschi C, et al. Applying hydrodynamic pressure to efficiently generate induced pluripotent stem cells via reprogramming of centenarian skin fibroblasts. PLoS ONE. 2019;14:e0215490 pubmed publisher
Kolundžić E, Ofenbauer A, Bulut S, Uyar B, Baytek G, Sommermeier A, et al. FACT Sets a Barrier for Cell Fate Reprogramming in Caenorhabditis elegans and Human Cells. Dev Cell. 2018;46:611-626.e12 pubmed publisher
El Battrawy I, Lan H, Cyganek L, Zhao Z, Li X, Buljubasic F, et al. Modeling Short QT Syndrome Using Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes. J Am Heart Assoc. 2018;7: pubmed publisher
Jansch C, Günther K, Waider J, Ziegler G, Forero A, Kollert S, et al. Generation of a human induced pluripotent stem cell (iPSC) line from a 51-year-old female with attention-deficit/hyperactivity disorder (ADHD) carrying a duplication of SLC2A3. Stem Cell Res. 2018;28:136-140 pubmed publisher
Ho J, Cattoglio C, McSwiggen D, Tjian R, Fong Y. Regulation of DNA demethylation by the XPC DNA repair complex in somatic and pluripotent stem cells. Genes Dev. 2017;31:830-844 pubmed publisher
Josowitz R, Mulero Navarro S, Rodriguez N, Falce C, Cohen N, Ullian E, et al. Autonomous and Non-autonomous Defects Underlie Hypertrophic Cardiomyopathy in BRAF-Mutant hiPSC-Derived Cardiomyocytes. Stem Cell Reports. 2016;7:355-369 pubmed publisher
Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
Ghosh K, Selokar N, Gahlawat S, Kumar D, Kumar P, Yadav P. Amnion Epithelial Cells of Buffalo (Bubalus Bubalis) Term Placenta Expressed Embryonic Stem Cells Markers and Differentiated into Cells of Neurogenic Lineage In Vitro. Anim Biotechnol. 2016;27:38-43 pubmed publisher
Johansson M, Dedic B, Lundholm K, Branzell F, Barone A, Benktander J, et al. Characterization of moose intestinal glycosphingolipids. Glycoconj J. 2015;32:393-412 pubmed publisher
Eller C, Yang G, Ouerfelli O, Raines R. Affinity of monoclonal antibodies for Globo-series glycans. Carbohydr Res. 2014;397:1-6 pubmed publisher
Schwartz C, Cheng A, Mughal M, Mattson M, Yao P. Clathrin assembly proteins AP180 and CALM in the embryonic rat brain. J Comp Neurol. 2010;518:3803-18 pubmed publisher
Kannagi R, Cochran N, Ishigami F, Hakomori S, Andrews P, Knowles B, et al. Stage-specific embryonic antigens (SSEA-3 and -4) are epitopes of a unique globo-series ganglioside isolated from human teratocarcinoma cells. EMBO J. 1983;2:2355-61 pubmed

product information

Product Type :

Antibody

Product Name :

SSEA4 Monoclonal Antibody (MC-813-70)

Catalog # :

MA1-021

Quantity :

100 ug

Price :

US 399.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 1:50-1:100, Immunocytochemistry: 1:100-1:500

Species :

Human

Clone :

MC-813-70

Isotype :

IgG3

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

SSEA-4 (Stage-specific embryonic antigen 4) is a cell surface antigen, expressed along with SSEA-3, TRA-1-60 and TRA-1-81 in embryonic stem cells, embryonal carcinoma cells and induced pluripotent stem cells (iPS). In human cells, these surface markers are down-regulated during the differentiation process, while SSEA-1 is absent in undifferentiated human stem cells and upregulated on the cell surface after retinoic acid mediated differentiation. Conversely, in mouse stem cells, SSEA-1 expression decreases with differentiation while SSEA-3 and SSEA-4 expression increase.

Immunogen :

human embryonal carcinoma cell line 2102Ep

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:50-1:100, Immunocytochemistry: 1:100-1:500

Aliases :

SSEA-4; stage-specific embryonic antigen 4